190 related articles for article (PubMed ID: 34278489)
1. Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ
Xu D; Yang P; Yang ZJ; Li QG; Ouyang YT; Yu T; Shangguan JH; Wan YY; Jiang LP; Qu XH; Han XJ
Mol Med Rep; 2021 Sep; 24(3):. PubMed ID: 34278489
[TBL] [Abstract][Full Text] [Related]
2. The role of Cdk5-mediated Drp1 phosphorylation in Aβ
Guo MY; Shang L; Hu YY; Jiang LP; Wan YY; Zhou QQ; Zhang K; Liao HF; Yi JL; Han XJ
J Cell Biochem; 2018 Jun; 119(6):4815-4825. PubMed ID: 29345339
[TBL] [Abstract][Full Text] [Related]
3. Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
Kim DI; Lee KH; Gabr AA; Choi GE; Kim JS; Ko SH; Han HJ
Biochim Biophys Acta; 2016 Nov; 1863(11):2820-2834. PubMed ID: 27599716
[TBL] [Abstract][Full Text] [Related]
4. Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease.
Yan J; Liu XH; Han MZ; Wang YM; Sun XL; Yu N; Li T; Su B; Chen ZY
Neurobiol Aging; 2015 Jan; 36(1):211-27. PubMed ID: 25192600
[TBL] [Abstract][Full Text] [Related]
5. Amyloid β-42 induces neuronal apoptosis by targeting mitochondria.
Han XJ; Hu YY; Yang ZJ; Jiang LP; Shi SL; Li YR; Guo MY; Wu HL; Wan YY
Mol Med Rep; 2017 Oct; 16(4):4521-4528. PubMed ID: 28849115
[TBL] [Abstract][Full Text] [Related]
6. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
[TBL] [Abstract][Full Text] [Related]
8. CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.
Jahani-Asl A; Huang E; Irrcher I; Rashidian J; Ishihara N; Lagace DC; Slack RS; Park DS
Hum Mol Genet; 2015 Aug; 24(16):4573-83. PubMed ID: 26002103
[TBL] [Abstract][Full Text] [Related]
9. Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization.
Lapresa R; Agulla J; Sánchez-Morán I; Zamarreño R; Prieto E; Bolaños JP; Almeida A
Neuropharmacology; 2019 Mar; 146():19-27. PubMed ID: 30452955
[TBL] [Abstract][Full Text] [Related]
10. Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Kandimalla R; Manczak M; Fry D; Suneetha Y; Sesaki H; Reddy PH
Hum Mol Genet; 2016 Nov; 25(22):4881-4897. PubMed ID: 28173111
[TBL] [Abstract][Full Text] [Related]
11. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Manczak M; Reddy PH
Hum Mol Genet; 2012 Jun; 21(11):2538-47. PubMed ID: 22367970
[TBL] [Abstract][Full Text] [Related]
12. Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimer's disease.
Bera A; Lavanya G; Reshmi R; Dev K; Kumar R
Eur J Neurosci; 2022 Nov; 56(9):5516-5531. PubMed ID: 35078269
[TBL] [Abstract][Full Text] [Related]
13. CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPP
Yang SH; Huang CY; Hsieh CY; Chuang JI
Mol Neurobiol; 2020 Oct; 57(10):4090-4105. PubMed ID: 32666227
[TBL] [Abstract][Full Text] [Related]
14. CDK5 inhibition protects against OGDR induced mitochondrial fragmentation and apoptosis through regulation of Drp1S616 phosphorylation.
Chen C; Peng X; Tang J; Hu Z; Tan J; Zeng L
Life Sci; 2021 Mar; 269():119062. PubMed ID: 33476635
[TBL] [Abstract][Full Text] [Related]
15. Effects and mechanism of amyloid β1-42 on mitochondria in astrocytes.
Yao Y; Huang JZ; Chen Y; Hu HJ; Tang X; Li X
Mol Med Rep; 2018 May; 17(5):6997-7004. PubMed ID: 29568933
[TBL] [Abstract][Full Text] [Related]
16. Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells.
Park SJ; Bae JE; Jo DS; Kim JB; Park NY; Fang J; Jung YK; Jo DG; Cho DH
Mol Brain; 2021 Jan; 14(1):6. PubMed ID: 33422108
[TBL] [Abstract][Full Text] [Related]
17. CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation.
Cho B; Cho HM; Kim HJ; Jeong J; Park SK; Hwang EM; Park JY; Kim WR; Kim H; Sun W
Exp Mol Med; 2014 Jul; 46(7):e105. PubMed ID: 25012575
[TBL] [Abstract][Full Text] [Related]
18. Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
Kuruva CS; Manczak M; Yin X; Ogunmokun G; Reddy AP; Reddy PH
Hum Mol Genet; 2017 Sep; 26(17):3375-3395. PubMed ID: 28854701
[TBL] [Abstract][Full Text] [Related]
19. Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation.
Lim JR; Lee HJ; Jung YH; Kim JS; Chae CW; Kim SY; Han HJ
Cell Commun Signal; 2020 Aug; 18(1):123. PubMed ID: 32787872
[TBL] [Abstract][Full Text] [Related]
20. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.
Cho DH; Nakamura T; Fang J; Cieplak P; Godzik A; Gu Z; Lipton SA
Science; 2009 Apr; 324(5923):102-5. PubMed ID: 19342591
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
