BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 34288118)

  • 1. Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
    Kumar D; Jha B; Bhatia I; Ashraf A; Dwivedy A; Biswal BK
    Proteins; 2022 Jan; 90(1):3-17. PubMed ID: 34288118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structures of native, substrate-bound and inhibited forms of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
    Ahangar MS; Vyas R; Nasir N; Biswal BK
    Acta Crystallogr D Biol Crystallogr; 2013 Dec; 69(Pt 12):2461-7. PubMed ID: 24311587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
    Rawson S; Bisson C; Hurdiss DL; Fazal A; McPhillie MJ; Sedelnikova SE; Baker PJ; Rice DW; Muench SP
    Proc Natl Acad Sci U S A; 2018 Feb; 115(8):1795-1800. PubMed ID: 29434040
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The active site of the
    Bashiri G; Grove TL; Hegde SS; Lagautriere T; Gerfen GJ; Almo SC; Squire CJ; Blanchard JS; Baker EN
    J Biol Chem; 2019 Aug; 294(35):13158-13170. PubMed ID: 31315931
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational insights into the role of structurally diverse plant secondary metabolites as inhibitors against Imidazole Glycerol Phosphate Dehydratase of
    Raguraman V; Chauhan L; Gehlot P; Kongkham B; Hariprasad P
    J Biomol Struct Dyn; 2023 Aug; ():1-13. PubMed ID: 37578041
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials.
    Rice CA; Campbell SJ; Bisson C; Owen HJ; Sedelnikova SE; Baker PJ; Rice DW; Henriquez FL; Roberts CW
    PLoS One; 2018; 13(7):e0198827. PubMed ID: 29969448
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Purification and characterization of the imidazoleglycerol-phosphate dehydratase of Saccharomyces cerevisiae from recombinant Escherichia coli.
    Hawkes TR; Thomas PG; Edwards LS; Rayner SJ; Wilkinson KW; Rice DW
    Biochem J; 1995 Mar; 306 ( Pt 2)(Pt 2):385-97. PubMed ID: 7887893
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and Function of the Refined C-Terminal Loop in Imidazole Glycerol Phosphate Dehydratase from Different Homologs.
    Wang L; Liu R; Meng Y; Li F; Lu H
    J Agric Food Chem; 2021 Nov; 69(46):13871-13880. PubMed ID: 34780187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
    Dong Y; Qiu X; Shaw N; Xu Y; Sun Y; Li X; Li J; Rao Z
    Protein Cell; 2015 Jul; 6(7):504-17. PubMed ID: 26081470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro activity and In vivo efficacy of Isoliquiritigenin against Staphylococcus xylosus ATCC 700404 by IGPD target.
    Qu Q; Wang J; Cui W; Zhou Y; Xing X; Che R; Liu X; Chen X; Bello-Onaghise G; Dong C; Li Z; Li X; Li Y
    PLoS One; 2019; 14(12):e0226260. PubMed ID: 31860659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in
    Singh V; Grzegorzewicz AE; Fienberg S; Müller R; Khonde LP; Sanz O; Alfonso S; Urones B; Drewes G; Bantscheff M; Ghidelli-Disse S; Ioerger TR; Angala B; Liu J; Lee RE; Sacchettini JC; Krieger IV; Jackson M; Chibale K; Ghorpade SR
    ACS Infect Dis; 2022 Nov; 8(11):2315-2326. PubMed ID: 36325756
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
    Bisson C; Britton KL; Sedelnikova SE; Rodgers HF; Eadsforth TC; Viner RC; Hawkes TR; Baker PJ; Rice DW
    Structure; 2015 Jul; 23(7):1236-45. PubMed ID: 26095028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purification, crystallization and preliminary crystallographic analysis of Arabidopsis thaliana imidazoleglycerol-phosphate dehydratase.
    Glynn SE; Baker PJ; Sedelnikova SE; Levy CW; Rodgers HF; Blank J; Hawkes TR; Rice DW
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Aug; 61(Pt 8):776-8. PubMed ID: 16511155
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of 9H-fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors.
    Suresh A; Srinivasarao S; Agnieszka N; Ewa AK; Alvala M; Lherbet C; Chandra Sekhar KVG
    Chem Biol Drug Des; 2018 Jun; 91(6):1078-1086. PubMed ID: 29063733
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching.
    Schweitzer BA; Loida PJ; CaJacob CA; Chott RC; Collantes EM; Hegde SG; Mosier PD; Profeta S
    Bioorg Med Chem Lett; 2002 Jul; 12(13):1743-6. PubMed ID: 12067551
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and structural characterization of a histidinol phosphate phosphatase from
    Jha B; Kumar D; Sharma A; Dwivedy A; Singh R; Biswal BK
    J Biol Chem; 2018 Jun; 293(26):10102-10118. PubMed ID: 29752410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HisB from Mycobacterium tuberculosis: cloning, overexpression in Mycobacterium smegmatis, purification, crystallization and preliminary X-ray crystallographic analysis.
    Ahangar MS; Khandokar Y; Nasir N; Vyas R; Biswal BK
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Nov; 67(Pt 11):1451-6. PubMed ID: 22102255
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues.
    Shrivastava P; Navratna V; Silla Y; Dewangan RP; Pramanik A; Chaudhary S; Rayasam G; Kumar A; Gopal B; Ramachandran S
    Sci Rep; 2016 Aug; 6():30827. PubMed ID: 27501775
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-and-mechanism-based design and discovery of type II Mycobacterium tuberculosis dehydroquinate dehydratase inhibitors.
    Yao Y; Li ZS
    Curr Top Med Chem; 2014; 14(1):51-63. PubMed ID: 24236726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA; Moon JY; Lee SC; Ryoo SW; Yoon MY
    Biochim Biophys Acta; 2015 Oct; 1854(10 Pt A):1338-50. PubMed ID: 25988243
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.