These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia. Cao Y; Hunter ZR; Liu X; Xu L; Yang G; Chen J; Patterson CJ; Tsakmaklis N; Kanan S; Rodig S; Castillo JJ; Treon SP Leukemia; 2015 Jan; 29(1):169-76. PubMed ID: 24912431 [TBL] [Abstract][Full Text] [Related]
24. A multicenter, open-label, phase II study of tirabrutinib (ONO/GS-4059) in patients with Waldenström's macroglobulinemia. Sekiguchi N; Rai S; Munakata W; Suzuki K; Handa H; Shibayama H; Endo T; Terui Y; Iwaki N; Fukuhara N; Tatetsu H; Iida S; Ishikawa T; Shiibashi R; Izutsu K Cancer Sci; 2020 Sep; 111(9):3327-3337. PubMed ID: 32639651 [TBL] [Abstract][Full Text] [Related]
25. Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status. Cea M; Cagnetta A; Acharya C; Acharya P; Tai YT; Yang C; Lovera D; Soncini D; Miglino M; Fraternali-Orcioni G; Mastracci L; Nencioni A; Montecucco F; Monacelli F; Ballestrero A; Hideshima T; Chauhan D; Gobbi M; Lemoli RM; Munshi N; Treon SP; Anderson KC Clin Cancer Res; 2016 Dec; 22(24):6099-6109. PubMed ID: 27287071 [TBL] [Abstract][Full Text] [Related]
26. TP53 mutations are associated with mutated MYD88 and CXCR4, and confer an adverse outcome in Waldenström macroglobulinaemia. Gustine JN; Tsakmaklis N; Demos MG; Kofides A; Chen JG; Liu X; Munshi M; Guerrera ML; Chan GG; Patterson CJ; Meid K; Dubeau T; Yang G; Hunter ZR; Treon SP; Castillo JJ; Xu L Br J Haematol; 2019 Jan; 184(2):242-245. PubMed ID: 30183082 [TBL] [Abstract][Full Text] [Related]
27. Plamotamab (XmAb Parrondo RD; Paulus A; Alegria V; Liebowitz D; Johnson C; Clynes R; Roy V; Menke DM; Jiang L; Chanan-Khan AA; Ailawadhi S Leuk Lymphoma; 2022 Mar; 63(3):738-742. PubMed ID: 34781809 [No Abstract] [Full Text] [Related]
28. CXCR4 mutation subtypes impact response and survival outcomes in patients with Waldenström macroglobulinaemia treated with ibrutinib. Castillo JJ; Xu L; Gustine JN; Keezer A; Meid K; Dubeau TE; Liu X; Demos MG; Kofides A; Tsakmaklis N; Chen JG; Munshi M; Guerrera ML; Chan GG; Patterson CJ; Yang G; Hunter ZR; Treon SP Br J Haematol; 2019 Nov; 187(3):356-363. PubMed ID: 31267520 [TBL] [Abstract][Full Text] [Related]
29. Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia. Xu L; Tsakmaklis N; Yang G; Chen JG; Liu X; Demos M; Kofides A; Patterson CJ; Meid K; Gustine J; Dubeau T; Palomba ML; Advani R; Castillo JJ; Furman RR; Hunter ZR; Treon SP Blood; 2017 May; 129(18):2519-2525. PubMed ID: 28235842 [TBL] [Abstract][Full Text] [Related]
31. Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia. Treon SP; Cao Y; Xu L; Yang G; Liu X; Hunter ZR Blood; 2014 May; 123(18):2791-6. PubMed ID: 24553177 [TBL] [Abstract][Full Text] [Related]
32. Management of Waldenström macroglobulinemia in 2020. Castillo JJ; Treon SP Hematology Am Soc Hematol Educ Program; 2020 Dec; 2020(1):372-379. PubMed ID: 33275726 [TBL] [Abstract][Full Text] [Related]
33. A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study. Tam CS; Opat S; D'Sa S; Jurczak W; Lee HP; Cull G; Owen RG; Marlton P; Wahlin BE; Sanz RG; McCarthy H; Mulligan S; Tedeschi A; Castillo JJ; Czyz J; Fernández de Larrea C; Belada D; Libby E; Matous JV; Motta M; Siddiqi T; Tani M; Trneny M; Minnema MC; Buske C; Leblond V; Trotman J; Chan WY; Schneider J; Ro S; Cohen A; Huang J; Dimopoulos M Blood; 2020 Oct; 136(18):2038-2050. PubMed ID: 32731259 [TBL] [Abstract][Full Text] [Related]
34. Novel Treatment Strategies in the Management of Waldenström Macroglobulinemia. Zanwar S; Abeykoon JP; Kapoor P Curr Hematol Malig Rep; 2020 Feb; 15(1):31-43. PubMed ID: 32006301 [TBL] [Abstract][Full Text] [Related]
35. Plasmablastic lymphoma transformation in a patient with Waldenström macroglobulinemia treated with ibrutinib. Castillo JJ; LaMacchia J; Flynn CA; Sarosiek S; Pozdnyakova O; Treon SP Br J Haematol; 2021 Nov; 195(3):466-468. PubMed ID: 34355802 [No Abstract] [Full Text] [Related]
36. The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. Yang G; Wang J; Tan L; Munshi M; Liu X; Kofides A; Chen JG; Tsakmaklis N; Demos MG; Guerrera ML; Xu L; Hunter ZR; Che J; Patterson CJ; Meid K; Castillo JJ; Munshi NC; Anderson KC; Cameron M; Buhrlage SJ; Gray NS; Treon SP Blood; 2021 Nov; 138(20):1966-1979. PubMed ID: 34132782 [TBL] [Abstract][Full Text] [Related]
37. Partial response or better at six months is prognostic of superior progression-free survival in Waldenström macroglobulinaemia patients treated with ibrutinib. Castillo JJ; Abeykoon JP; Gustine JN; Zanwar S; Mein K; Flynn CA; Demos MG; Guerrera ML; Kofides A; Liu X; Munshi M; Tsakmaklis N; King R; Yang G; Hunter ZR; Advani RH; Palomba ML; Ansell SM; Gertz MA; Kapoor P; Treon SP Br J Haematol; 2021 Feb; 192(3):542-550. PubMed ID: 33207010 [TBL] [Abstract][Full Text] [Related]
38. Zanubrutinib for the treatment of patients with Waldenström macroglobulinemia: 3 years of follow-up. Trotman J; Opat S; Gottlieb D; Simpson D; Marlton P; Cull G; Munoz J; Tedeschi A; Roberts AW; Seymour JF; Atwal SK; Yu Y; Novotny W; Holmgren E; Tan Z; Hilger JD; Huang J; Tam CS Blood; 2020 Oct; 136(18):2027-2037. PubMed ID: 32698195 [TBL] [Abstract][Full Text] [Related]
39. Ibrutinib for the treatment of Waldenström macroglobulinemia. Chakraborty R; Kapoor P; Ansell SM; Gertz MA Expert Rev Hematol; 2015 Oct; 8(5):569-79. PubMed ID: 26138997 [TBL] [Abstract][Full Text] [Related]
40. A Phase II Trial of the Bruton Tyrosine-Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Relapsed/Refractory Waldenström Macroglobulinemia. An G; Zhou D; Cheng S; Zhou K; Li J; Zhou J; Xie L; Jin J; Zhong L; Yan L; Guo H; Du C; Zhong J; Yu Y; Wu B; Qiu L Clin Cancer Res; 2021 Oct; 27(20):5492-5501. PubMed ID: 34253577 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]