BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 34298883)

  • 1. Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas.
    Cook KM; Shen H; McKelvey KJ; Gee HE; Hau E
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298883
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas.
    Mudassar F; Shen H; O'Neill G; Hau E
    J Exp Clin Cancer Res; 2020 Oct; 39(1):208. PubMed ID: 33028364
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sensitization of Glioblastoma Cells to Irradiation by Modulating the Glucose Metabolism.
    Shen H; Hau E; Joshi S; Dilda PJ; McDonald KL
    Mol Cancer Ther; 2015 Aug; 14(8):1794-804. PubMed ID: 26063767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effect of dichloroacetate in canine prostate adenocarcinomas and transitional cell carcinomas in vitro.
    Harting T; Stubbendorff M; Willenbrock S; Wagner S; Schadzek P; Ngezahayo A; Murua Escobar HM; Nolte I
    Int J Oncol; 2016 Dec; 49(6):2341-2350. PubMed ID: 27748833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells.
    Allen KT; Chin-Sinex H; DeLuca T; Pomerening JR; Sherer J; Watkins JB; Foley J; Jesseph JM; Mendonca MS
    Free Radic Biol Med; 2015 Dec; 89():263-73. PubMed ID: 26393423
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
    Tataranni T; Agriesti F; Pacelli C; Ruggieri V; Laurenzana I; Mazzoccoli C; Sala GD; Panebianco C; Pazienza V; Capitanio N; Piccoli C
    Cells; 2019 May; 8(5):. PubMed ID: 31109089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual-targeting of aberrant glucose metabolism in glioblastoma.
    Shen H; Decollogne S; Dilda PJ; Hau E; Chung SA; Luk PP; Hogg PJ; McDonald KL
    J Exp Clin Cancer Res; 2015 Feb; 34(1):14. PubMed ID: 25652202
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas.
    Shen H; Cook K; Gee HE; Hau E
    J Exp Clin Cancer Res; 2020 Jul; 39(1):129. PubMed ID: 32631383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
    Zhang W; Hu X; Zhou W; Tam KY
    J Proteome Res; 2018 Sep; 17(9):3012-3021. PubMed ID: 30028142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells.
    Ho N; Coomber BL
    Exp Cell Res; 2015 Feb; 331(1):73-81. PubMed ID: 25536473
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A; Kant S; Singh SM
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
    Kinnaird A; Dromparis P; Saleme B; Gurtu V; Watson K; Paulin R; Zervopoulos S; Stenson T; Sutendra G; Pink DB; Carmine-Simmen K; Moore R; Lewis JD; Michelakis ED
    Eur Urol; 2016 Apr; 69(4):734-744. PubMed ID: 26433571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas.
    Shen H; Yu M; Tsoli M; Chang C; Joshi S; Liu J; Ryall S; Chornenkyy Y; Siddaway R; Hawkins C; Ziegler DS
    Neuro Oncol; 2020 Jan; 22(1):139-151. PubMed ID: 31398252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism.
    Moreno-Sánchez R; Marín-Hernández Á; Del Mazo-Monsalvo I; Saavedra E; Rodríguez-Enríquez S
    Biochim Biophys Acta Gen Subj; 2017 Jan; 1861(1 Pt A):3221-3236. PubMed ID: 27538376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells.
    de Mey S; Dufait I; Jiang H; Corbet C; Wang H; Van De Gucht M; Kerkhove L; Law KL; Vandenplas H; Gevaert T; Feron O; De Ridder M
    Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33316932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dichloroacetate induces tumor-specific radiosensitivity in vitro but attenuates radiation-induced tumor growth delay in vivo.
    Zwicker F; Kirsner A; Peschke P; Roeder F; Debus J; Huber PE; Weber KJ
    Strahlenther Onkol; 2013 Aug; 189(8):684-92. PubMed ID: 23793865
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
    Neveu MA; De Preter G; Joudiou N; Bol A; Brender JR; Saito K; Kishimoto S; Grégoire V; Jordan BF; Krishna MC; Feron O; Gallez B
    Oncotarget; 2016 Dec; 7(49):81741-81749. PubMed ID: 28082726
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
    Ruggieri V; Agriesti F; Scrima R; Laurenzana I; Perrone D; Tataranni T; Mazzoccoli C; Lo Muzio L; Capitanio N; Piccoli C
    Oncotarget; 2015 Jan; 6(2):1217-30. PubMed ID: 25544754
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm?
    Papandreou I; Goliasova T; Denko NC
    Int J Cancer; 2011 Mar; 128(5):1001-8. PubMed ID: 20957634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-β Small Molecule Inhibitor.
    Bayin NS; Ma L; Thomas C; Baitalmal R; Sure A; Fansiwala K; Bustoros M; Golfinos JG; Pacione D; Snuderl M; Zagzag D; Barcellos-Hoff MH; Placantonakis D
    Neoplasia; 2016 Dec; 18(12):795-805. PubMed ID: 27978994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.