BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 34302498)

  • 1. Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.
    Nazio F; Po A; Abballe L; Ballabio C; Diomedi Camassei F; Bordi M; Camera A; Caruso S; Caruana I; Pezzullo M; Ferraina C; Milletti G; Gianesello M; Reddel S; De Luca CD; Ceglie D; Marinelli S; Campello S; Papaleo E; Miele E; Cacchione A; Carai A; Vinci M; Velardi E; De Angelis B; Tiberi L; Quintarelli C; Mastronuzzi A; Ferretti E; Locatelli F; Cecconi F
    Acta Neuropathol; 2021 Sep; 142(3):537-564. PubMed ID: 34302498
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of STAT3 NH
    Ray S; Coulter DW; Gray SD; Sughroue JA; Roychoudhury S; McIntyre EM; Chaturvedi NK; Bhakat KK; Joshi SS; McGuire TR; Sharp JG
    Mol Carcinog; 2018 Apr; 57(4):536-548. PubMed ID: 29280516
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
    Cianfanelli V; Fuoco C; Lorente M; Salazar M; Quondamatteo F; Gherardini PF; De Zio D; Nazio F; Antonioli M; D'Orazio M; Skobo T; Bordi M; Rohde M; Dalla Valle L; Helmer-Citterich M; Gretzmeier C; Dengjel J; Fimia GM; Piacentini M; Di Bartolomeo S; Velasco G; Cecconi F
    Nat Cell Biol; 2015 Jan; 17(1):20-30. PubMed ID: 25438055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma.
    Chaturvedi NK; Kling MJ; Griggs CN; Kesherwani V; Shukla M; McIntyre EM; Ray S; Liu Y; McGuire TR; Sharp JG; Band H; Joshi SS; Coulter DW
    Mol Cancer Ther; 2020 Jun; 19(6):1351-1362. PubMed ID: 32371591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. shRNA-mediated AMBRA1 knockdown reduces the cisplatin-induced autophagy and sensitizes ovarian cancer cells to cisplatin.
    Li X; Zhang L; Yu L; Wei W; Lin X; Hou X; Tian Y
    J Toxicol Sci; 2016 Feb; 41(1):45-53. PubMed ID: 26763392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.
    Bolin S; Borgenvik A; Persson CU; Sundström A; Qi J; Bradner JE; Weiss WA; Cho YJ; Weishaupt H; Swartling FJ
    Oncogene; 2018 May; 37(21):2850-2862. PubMed ID: 29511348
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy.
    Ranjan A; Kaushik I; Srivastava SK
    Cells; 2020 Sep; 9(9):. PubMed ID: 32971907
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of phosphorylated STAT3 by cucurbitacin I enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells.
    Chang CJ; Chiang CH; Song WS; Tsai SK; Woung LC; Chang CH; Jeng SY; Tsai CY; Hsu CC; Lee HF; Huang CS; Yung MC; Liu JH; Lu KH
    Childs Nerv Syst; 2012 Mar; 28(3):363-73. PubMed ID: 22249380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation.
    Cianfanelli V; D'Orazio M; Cecconi F
    Cell Cycle; 2015; 14(7):959-63. PubMed ID: 25803737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling.
    Li C; Li H; Zhang P; Yu LJ; Huang TM; Song X; Kong QY; Dong JL; Li PN; Liu J
    Nutrients; 2016 Dec; 9(1):. PubMed ID: 28035977
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.
    Venkataraman S; Alimova I; Balakrishnan I; Harris P; Birks DK; Griesinger A; Amani V; Cristiano B; Remke M; Taylor MD; Handler M; Foreman NK; Vibhakar R
    Oncotarget; 2014 May; 5(9):2355-71. PubMed ID: 24796395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.
    Diaz RJ; Golbourn B; Faria C; Picard D; Shih D; Raynaud D; Leadly M; MacKenzie D; Bryant M; Bebenek M; Smith CA; Taylor MD; Huang A; Rutka JT
    Oncotarget; 2015 Feb; 6(5):3359-74. PubMed ID: 25739120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
    Henssen A; Thor T; Odersky A; Heukamp L; El-Hindy N; Beckers A; Speleman F; Althoff K; Schäfers S; Schramm A; Sure U; Fleischhack G; Eggert A; Schulte JH
    Oncotarget; 2013 Nov; 4(11):2080-95. PubMed ID: 24231268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1.
    Capizzi M; Strappazzon F; Cianfanelli V; Papaleo E; Cecconi F
    Autophagy; 2017 Mar; 13(3):554-566. PubMed ID: 28059583
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells.
    Wang H; Wang L; Cao L; Zhang Q; Song Q; Meng Z; Wu X; Xu K
    Mol Carcinog; 2018 Apr; 57(4):522-535. PubMed ID: 29278657
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of Inhibitors of Apoptosis Proteins in Combination with Conventional Chemotherapy Leads to Synergistic Antitumor Activity in Medulloblastoma and Cancer Stem-Like Cells.
    Chen SM; Li YY; Tu CH; Salazar N; Tseng YY; Huang SF; Hsieh LL; Lui TN
    PLoS One; 2016; 11(8):e0161299. PubMed ID: 27537345
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Celecoxib suppresses the phosphorylation of STAT3 protein and can enhance the radiosensitivity of medulloblastoma-derived cancer stem-like cells.
    Yang MY; Lee HT; Chen CM; Shen CC; Ma HI
    Int J Mol Sci; 2014 Jun; 15(6):11013-29. PubMed ID: 24945311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.
    Zhao D; Pan C; Sun J; Gilbert C; Drews-Elger K; Azzam DJ; Picon-Ruiz M; Kim M; Ullmer W; El-Ashry D; Creighton CJ; Slingerland JM
    Oncogene; 2015 Jun; 34(24):3107-19. PubMed ID: 25151964
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Clinicopathological Significance and Correlative Signaling Pathways of an Autophagy-Related Gene, Ambra1, in Breast Cancer: a Study of 25 Microarray RNA-Seq Datasets and in-House Gene Silencing.
    He RQ; Xiong DD; Ma J; Hu XH; Chen G; Sun WL
    Cell Physiol Biochem; 2018; 51(3):1027-1040. PubMed ID: 30476925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD133
    Garg N; Bakhshinyan D; Venugopal C; Mahendram S; Rosa DA; Vijayakumar T; Manoranjan B; Hallett R; McFarlane N; Delaney KH; Kwiecien JM; Arpin CC; Lai PS; Gómez-Biagi RF; Ali AM; de Araujo ED; Ajani OA; Hassell JA; Gunning PT; Singh SK
    Oncogene; 2017 Feb; 36(5):606-617. PubMed ID: 27775079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.