232 related articles for article (PubMed ID: 34302810)
1. Solution structures of human myeloma IgG3 antibody reveal extended Fab and Fc regions relative to the other IgG subclasses.
Spiteri VA; Goodall M; Doutch J; Rambo RP; Gor J; Perkins SJ
J Biol Chem; 2021 Sep; 297(3):100995. PubMed ID: 34302810
[TBL] [Abstract][Full Text] [Related]
2. The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions.
Hui GK; Gardener AD; Begum H; Eldrid C; Thalassinos K; Gor J; Perkins SJ
J Biol Chem; 2019 Jul; 294(28):10789-10806. PubMed ID: 31088911
[TBL] [Abstract][Full Text] [Related]
3. The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling.
Boehm MK; Woof JM; Kerr MA; Perkins SJ
J Mol Biol; 1999 Mar; 286(5):1421-47. PubMed ID: 10064707
[TBL] [Abstract][Full Text] [Related]
4. Using atomistic solution scattering modelling to elucidate the role of the Fc glycans in human IgG4.
Spiteri VA; Doutch J; Rambo RP; Bhatt JS; Gor J; Dalby PA; Perkins SJ
PLoS One; 2024; 19(4):e0300964. PubMed ID: 38557973
[TBL] [Abstract][Full Text] [Related]
5. Solution structure of deglycosylated human IgG1 shows the role of C
Spiteri VA; Doutch J; Rambo RP; Gor J; Dalby PA; Perkins SJ
Biophys J; 2021 May; 120(9):1814-1834. PubMed ID: 33675758
[TBL] [Abstract][Full Text] [Related]
6. The Fab conformations in the solution structure of human immunoglobulin G4 (IgG4) restrict access to its Fc region: implications for functional activity.
Rayner LE; Hui GK; Gor J; Heenan RK; Dalby PA; Perkins SJ
J Biol Chem; 2014 Jul; 289(30):20740-56. PubMed ID: 24876381
[TBL] [Abstract][Full Text] [Related]
7. Atomistic Modeling of Scattering Curves for Human IgG1/4 Reveals New Structure-Function Insights.
Wright DW; Elliston ELK; Hui GK; Perkins SJ
Biophys J; 2019 Dec; 117(11):2101-2119. PubMed ID: 31708160
[TBL] [Abstract][Full Text] [Related]
8. Demonstration by pulsed neutron scattering that the arrangement of the Fab and Fc fragments in the overall structures of bovine IgG1 and IgG2 in solution is similar.
Mayans MO; Coadwell WJ; Beale D; Symons DB; Perkins SJ
Biochem J; 1995 Oct; 311 ( Pt 1)(Pt 1):283-91. PubMed ID: 7575466
[TBL] [Abstract][Full Text] [Related]
9. The solution structures of two human IgG1 antibodies show conformational stability and accommodate their C1q and FcγR ligands.
Rayner LE; Hui GK; Gor J; Heenan RK; Dalby PA; Perkins SJ
J Biol Chem; 2015 Mar; 290(13):8420-38. PubMed ID: 25659433
[TBL] [Abstract][Full Text] [Related]
10. Conformation of human IgG subclasses in solution. Small-angle X-ray scattering and hydrodynamic studies.
Kilár F; Simon I; Lakatos S; Vonderviszt F; Medgyesi GA; Závodszky P
Eur J Biochem; 1985 Feb; 147(1):17-25. PubMed ID: 3971974
[TBL] [Abstract][Full Text] [Related]
11. The solution conformations of the subclasses of human IgG deduced from sedimentation and small angle X-ray scattering studies.
Gregory L; Davis KG; Sheth B; Boyd J; Jefferis R; Nave C; Burton DR
Mol Immunol; 1987 Aug; 24(8):821-9. PubMed ID: 3657808
[TBL] [Abstract][Full Text] [Related]
12. Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering.
Sun Z; Almogren A; Furtado PB; Chowdhury B; Kerr MA; Perkins SJ
J Mol Biol; 2005 Oct; 353(1):155-73. PubMed ID: 16157351
[TBL] [Abstract][Full Text] [Related]
13. Masking of the Fc region in human IgG4 by constrained X-ray scattering modelling: implications for antibody function and therapy.
Abe Y; Gor J; Bracewell DG; Perkins SJ; Dalby PA
Biochem J; 2010 Nov; 432(1):101-11. PubMed ID: 20722630
[TBL] [Abstract][Full Text] [Related]
14. The solution structures of native and patient monomeric human IgA1 reveal asymmetric extended structures: implications for function and IgAN disease.
Hui GK; Wright DW; Vennard OL; Rayner LE; Pang M; Yeo SC; Gor J; Molyneux K; Barratt J; Perkins SJ
Biochem J; 2015 Oct; 471(2):167-85. PubMed ID: 26268558
[TBL] [Abstract][Full Text] [Related]
15. The solution structure of the heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions.
Gao X; Thrush JW; Gor J; Naismith JH; Owens RJ; Perkins SJ
J Biol Chem; 2023 Nov; 299(11):105337. PubMed ID: 37838175
[TBL] [Abstract][Full Text] [Related]
16. The solution structure of rabbit IgG accounts for its interactions with the Fc receptor and complement C1q and its conformational stability.
Rayner LE; Kadkhodayi-Kholghi N; Heenan RK; Gor J; Dalby PA; Perkins SJ
J Mol Biol; 2013 Feb; 425(3):506-23. PubMed ID: 23178865
[TBL] [Abstract][Full Text] [Related]
17. Extended flexible linker structures in the complement chimaeric conjugate CR2-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.
Gilbert HE; Aslam M; Guthridge JM; Holers VM; Perkins SJ
J Mol Biol; 2006 Feb; 356(2):397-412. PubMed ID: 16375923
[TBL] [Abstract][Full Text] [Related]
18. Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation.
Perkins SJ; Nealis AS; Sutton BJ; Feinstein A
J Mol Biol; 1991 Oct; 221(4):1345-66. PubMed ID: 1942055
[TBL] [Abstract][Full Text] [Related]
19. Structural characterization of the Man5 glycoform of human IgG3 Fc.
Shah IS; Lovell S; Mehzabeen N; Battaile KP; Tolbert TJ
Mol Immunol; 2017 Dec; 92():28-37. PubMed ID: 29031045
[TBL] [Abstract][Full Text] [Related]
20. Solution structure determination of monomeric human IgA2 by X-ray and neutron scattering, analytical ultracentrifugation and constrained modelling: a comparison with monomeric human IgA1.
Furtado PB; Whitty PW; Robertson A; Eaton JT; Almogren A; Kerr MA; Woof JM; Perkins SJ
J Mol Biol; 2004 May; 338(5):921-41. PubMed ID: 15111057
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
