BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 34303079)

  • 1. Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer.
    Simov V; Altman MD; Bianchi E; DelRizzo S; DiNunzio EN; Feng G; Goldenblatt P; Ingenito R; Johnson SA; Mansueto MS; Mayhood T; Mortison JD; Serebrov V; Sondey C; Sriraman V; Tucker TJ; Walji A; Wan H; Yue Y; Stoeck A; DiMauro EF
    Eur J Med Chem; 2021 Nov; 224():113686. PubMed ID: 34303079
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stapled Peptides as Direct Inhibitors of Nrf2-sMAF Transcription Factors.
    Modi R; McKee N; Zhang N; Alwali A; Nelson S; Lohar A; Ostafe R; Zhang DD; Parkinson EI
    J Med Chem; 2023 May; 66(9):6184-6192. PubMed ID: 37097833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer.
    Kimura M; Yamamoto T; Zhang J; Itoh K; Kyo M; Kamiya T; Aburatani H; Katsuoka F; Kurokawa H; Tanaka T; Motohashi H; Yamamoto M
    J Biol Chem; 2007 Nov; 282(46):33681-33690. PubMed ID: 17875642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells.
    Katsuoka F; Otsuki A; Takahashi M; Ito S; Yamamoto M
    Mol Cell Biol; 2019 Oct; 39(20):. PubMed ID: 31383749
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.
    Wu T; Wang XJ; Tian W; Jaramillo MC; Lau A; Zhang DD
    Free Radic Biol Med; 2014 Feb; 67():69-80. PubMed ID: 24140708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.
    Katsuoka F; Motohashi H; Engel JD; Yamamoto M
    J Biol Chem; 2005 Feb; 280(6):4483-90. PubMed ID: 15574414
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.
    Yamamoto T; Kyo M; Kamiya T; Tanaka T; Engel JD; Motohashi H; Yamamoto M
    Genes Cells; 2006 Jun; 11(6):575-91. PubMed ID: 16716189
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.
    Hirotsu Y; Katsuoka F; Funayama R; Nagashima T; Nishida Y; Nakayama K; Engel JD; Yamamoto M
    Nucleic Acids Res; 2012 Nov; 40(20):10228-39. PubMed ID: 22965115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.
    Singh A; Venkannagari S; Oh KH; Zhang YQ; Rohde JM; Liu L; Nimmagadda S; Sudini K; Brimacombe KR; Gajghate S; Ma J; Wang A; Xu X; Shahane SA; Xia M; Woo J; Mensah GA; Wang Z; Ferrer M; Gabrielson E; Li Z; Rastinejad F; Shen M; Boxer MB; Biswal S
    ACS Chem Biol; 2016 Nov; 11(11):3214-3225. PubMed ID: 27552339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2.
    Alam J; Killeen E; Gong P; Naquin R; Hu B; Stewart D; Ingelfinger JR; Nath KA
    Am J Physiol Renal Physiol; 2003 Apr; 284(4):F743-52. PubMed ID: 12453873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells.
    Caggiano R; Cattaneo F; Moltedo O; Esposito G; Perrino C; Trimarco B; Ammendola R; Faraonio R
    Oxid Med Cell Longev; 2017; 2017():9308310. PubMed ID: 29138682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cobalt induces heme oxygenase-1 expression by a hypoxia-inducible factor-independent mechanism in Chinese hamster ovary cells: regulation by Nrf2 and MafG transcription factors.
    Gong P; Hu B; Stewart D; Ellerbe M; Figueroa YG; Blank V; Beckman BS; Alam J
    J Biol Chem; 2001 Jul; 276(29):27018-25. PubMed ID: 11356853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
    Bloom D; Dhakshinamoorthy S; Jaiswal AK
    Oncogene; 2002 Mar; 21(14):2191-200. PubMed ID: 11948402
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
    Carino A; Biagioli M; Marchianò S; Fiorucci C; Bordoni M; Roselli R; Di Giorgio C; Baldoni M; Ricci P; Monti MC; Morretta E; Zampella A; Distrutti E; Fiorucci S
    Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Sep; 1865(9):158733. PubMed ID: 32371093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection.
    Otsuki A; Suzuki M; Katsuoka F; Tsuchida K; Suda H; Morita M; Shimizu R; Yamamoto M
    Free Radic Biol Med; 2016 Feb; 91():45-57. PubMed ID: 26677805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.
    Yang H; Ko K; Xia M; Li TW; Oh P; Li J; Lu SC
    Hepatology; 2010 Apr; 51(4):1291-301. PubMed ID: 20146260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis.
    Tian H; Zhang D; Gao Z; Li H; Zhang B; Zhang Q; Li L; Cheng Q; Pei D; Zheng J
    Cancer Gene Ther; 2014 Oct; 21(10):416-26. PubMed ID: 25236495
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction.
    Colarusso S; De Simone D; Frattarelli T; Andreini M; Cerretani M; Missineo A; Moretti D; Tambone S; Kempf G; Augustin M; Steinbacher S; Munoz-Sanjuan I; Park L; Summa V; Tomei L; Bresciani A; Dominguez C; Toledo-Sherman L; Bianchi E
    Bioorg Med Chem; 2020 Nov; 28(21):115738. PubMed ID: 33065433
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ARE-PROTACs Enable Co-degradation of an Nrf2-MafG Heterodimer.
    Ji J; Ma S; Zhu Y; Zhao J; Tong Y; You Q; Jiang Z
    J Med Chem; 2023 May; 66(9):6070-6081. PubMed ID: 36892138
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency.
    Lu MC; Jiao Q; Liu T; Tan SJ; Zhou HS; You QD; Jiang ZY
    Eur J Med Chem; 2018 Jan; 143():1578-1589. PubMed ID: 29117896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.