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6. Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth. Grohar PJ; Segars LE; Yeung C; Pommier Y; D'Incalci M; Mendoza A; Helman LJ Clin Cancer Res; 2014 Mar; 20(5):1190-203. PubMed ID: 24277455 [TBL] [Abstract][Full Text] [Related]
7. miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. Nakatani F; Ferracin M; Manara MC; Ventura S; Del Monaco V; Ferrari S; Alberghini M; Grilli A; Knuutila S; Schaefer KL; Mattia G; Negrini M; Picci P; Serra M; Scotlandi K J Pathol; 2012 Apr; 226(5):796-805. PubMed ID: 21960059 [TBL] [Abstract][Full Text] [Related]
8. Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing's sarcoma through the PI3K/Akt pathway. Ren C; Ren T; Yang K; Wang S; Bao X; Zhang F; Guo W J Exp Clin Cancer Res; 2016 Mar; 35():44. PubMed ID: 26969300 [TBL] [Abstract][Full Text] [Related]
9. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma. Boro A; Prêtre K; Rechfeld F; Thalhammer V; Oesch S; Wachtel M; Schäfer BW; Niggli FK Int J Cancer; 2012 Nov; 131(9):2153-64. PubMed ID: 22323082 [TBL] [Abstract][Full Text] [Related]
10. Preclinical Justification of pbi-shRNA EWS/FLI1 Lipoplex (LPX) Treatment for Ewing's Sarcoma. Rao DD; Jay C; Wang Z; Luo X; Kumar P; Eysenbach H; Ghisoli M; Senzer N; Nemunaitis J Mol Ther; 2016 Aug; 24(8):1412-22. PubMed ID: 27166877 [TBL] [Abstract][Full Text] [Related]
12. Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors. Tanaka M; Yamazaki Y; Kanno Y; Igarashi K; Aisaki K; Kanno J; Nakamura T J Clin Invest; 2014 Jul; 124(7):3061-74. PubMed ID: 24911143 [TBL] [Abstract][Full Text] [Related]
13. Discovery and Validation of a Compound to Target Ewing's Sarcoma. Esfandiari Nazzaro E; Sabei FY; Vogel WK; Nazari M; Nicholson KS; Gafken PR; Taratula O; Taratula O; Davare MA; Leid M Pharmaceutics; 2021 Sep; 13(10):. PubMed ID: 34683845 [TBL] [Abstract][Full Text] [Related]
14. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Leacock SW; Basse AN; Chandler GL; Kirk AM; Rakheja D; Amatruda JF Dis Model Mech; 2012 Jan; 5(1):95-106. PubMed ID: 21979944 [TBL] [Abstract][Full Text] [Related]
15. The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing's sarcoma. Sengupta A; Rahman M; Mateo-Lozano S; Tirado OM; Notario V Int J Oncol; 2013 Sep; 43(3):803-12. PubMed ID: 23857410 [TBL] [Abstract][Full Text] [Related]
16. Establishment of a novel patient-derived Ewing's sarcoma cell line, NCC-ES1-C1. Oyama R; Kito F; Qiao Z; Sakumoto M; Noguchi R; Takahashi M; Toki S; Tanzawa Y; Yoshida A; Kawai A; Kondo T In Vitro Cell Dev Biol Anim; 2018 Dec; 54(10):770-778. PubMed ID: 30324244 [TBL] [Abstract][Full Text] [Related]
17. The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago. Murakami T; Kiyuna T; Kawaguchi K; Igarashi K; Singh AS; Hiroshima Y; Zhang Y; Zhao M; Miyake K; Nelson SD; Dry SM; Li Y; DeLong JC; Lwin TM; Chishima T; Tanaka K; Bouvet M; Endo I; Eilber FC; Hoffman RM Cell Cycle; 2017 Jun; 16(11):1046-1052. PubMed ID: 28296559 [TBL] [Abstract][Full Text] [Related]
18. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Kinsey M; Smith R; Lessnick SL Mol Cancer Res; 2006 Nov; 4(11):851-9. PubMed ID: 17114343 [TBL] [Abstract][Full Text] [Related]
19. Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma. Heisey DAR; Jacob S; Lochmann TL; Kurupi R; Ghotra MS; Calbert ML; Shende M; Maves YK; Koblinski JE; Dozmorov MG; Boikos SA; Benes CH; Faber AC Mol Cancer Ther; 2021 Oct; 20(10):1868-1879. PubMed ID: 34315769 [TBL] [Abstract][Full Text] [Related]
20. Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma. Ban J; Jug G; Mestdagh P; Schwentner R; Kauer M; Aryee DN; Schaefer KL; Nakatani F; Scotlandi K; Reiter M; Strunk D; Speleman F; Vandesompele J; Kovar H Oncogene; 2011 May; 30(18):2173-80. PubMed ID: 21217773 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]