298 related articles for article (PubMed ID: 34305609)
1. Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease.
Avrutsky MI; Troy CM
Front Pharmacol; 2021; 12():701301. PubMed ID: 34305609
[TBL] [Abstract][Full Text] [Related]
2. CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis.
An HK; Chung KM; Park H; Hong J; Gim JE; Choi H; Lee YW; Choi J; Mun JY; Yu SW
Autophagy; 2020 Sep; 16(9):1598-1617. PubMed ID: 31818185
[TBL] [Abstract][Full Text] [Related]
3. Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac.
Huang Y; Rich RL; Myszka DG; Wu H
J Biol Chem; 2003 Dec; 278(49):49517-22. PubMed ID: 14512414
[TBL] [Abstract][Full Text] [Related]
4. Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation.
Baechler BL; Bloemberg D; Quadrilatero J
Autophagy; 2019 Sep; 15(9):1606-1619. PubMed ID: 30859901
[TBL] [Abstract][Full Text] [Related]
5. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
Bratton SB; Lewis J; Butterworth M; Duckett CS; Cohen GM
Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
[TBL] [Abstract][Full Text] [Related]
6. NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP.
Sun C; Cai M; Meadows RP; Xu N; Gunasekera AH; Herrmann J; Wu JC; Fesik SW
J Biol Chem; 2000 Oct; 275(43):33777-81. PubMed ID: 10934209
[TBL] [Abstract][Full Text] [Related]
7. Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
Cossu F; Milani M; Vachette P; Malvezzi F; Grassi S; Lecis D; Delia D; Drago C; Seneci P; Bolognesi M; Mastrangelo E
PLoS One; 2012; 7(11):e49527. PubMed ID: 23166698
[TBL] [Abstract][Full Text] [Related]
8. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
[TBL] [Abstract][Full Text] [Related]
9. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
[TBL] [Abstract][Full Text] [Related]
10. Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions.
Deegan S; Saveljeva S; Logue SE; Pakos-Zebrucka K; Gupta S; Vandenabeele P; Bertrand MJ; Samali A
Autophagy; 2014; 10(11):1921-36. PubMed ID: 25470234
[TBL] [Abstract][Full Text] [Related]
11. Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors.
Wang Z; Cuddy M; Samuel T; Welsh K; Schimmer A; Hanaii F; Houghten R; Pinilla C; Reed JC
J Biol Chem; 2004 Nov; 279(46):48168-76. PubMed ID: 15337764
[TBL] [Abstract][Full Text] [Related]
12. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
Gao Z; Tian Y; Wang J; Yin Q; Wu H; Li YM; Jiang X
J Biol Chem; 2007 Oct; 282(42):30718-27. PubMed ID: 17724022
[TBL] [Abstract][Full Text] [Related]
13. Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome.
Zhu H; Pytel P; Gomez CM
Hum Mol Genet; 2014 Jan; 23(1):69-77. PubMed ID: 23943790
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial biogenesis: pharmacological approaches.
Valero T
Curr Pharm Des; 2014; 20(35):5507-9. PubMed ID: 24606795
[TBL] [Abstract][Full Text] [Related]
15. Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells.
Hu D; Liu S; Shi L; Li C; Wu L; Fan Z
J Biol Chem; 2010 Jun; 285(24):18326-35. PubMed ID: 20406824
[TBL] [Abstract][Full Text] [Related]
16. A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy.
Chaudhary AK; Yadav N; Bhat TA; O'Malley J; Kumar S; Chandra D
Drug Discov Today; 2016 Jan; 21(1):38-47. PubMed ID: 26232549
[TBL] [Abstract][Full Text] [Related]
17. Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein.
O'Connor CL; Anguissola S; Huber HJ; Dussmann H; Prehn JH; Rehm M
Biochim Biophys Acta; 2008 Oct; 1783(10):1903-13. PubMed ID: 18590777
[TBL] [Abstract][Full Text] [Related]
18. XIAP: apoptotic brake and promising therapeutic target.
Holcik M; Gibson H; Korneluk RG
Apoptosis; 2001 Aug; 6(4):253-61. PubMed ID: 11445667
[TBL] [Abstract][Full Text] [Related]
19. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.
Nikolovska-Coleska Z; Meagher JL; Jiang S; Kawamoto SA; Gao W; Yi H; Qin D; Roller PP; Stuckey JA; Wang S
Anal Biochem; 2008 Mar; 374(1):87-98. PubMed ID: 18023397
[TBL] [Abstract][Full Text] [Related]
20. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.
Asselin E; Mills GB; Tsang BK
Cancer Res; 2001 Mar; 61(5):1862-8. PubMed ID: 11280739
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]