264 related articles for article (PubMed ID: 34312216)
1. CCT and CCT-Like Modular Protein Interaction Domains in WNK Signaling.
Taylor CA; Cobb MH
Mol Pharmacol; 2022 Apr; 101(4):201-212. PubMed ID: 34312216
[TBL] [Abstract][Full Text] [Related]
2. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
Vitari AC; Thastrup J; Rafiqi FH; Deak M; Morrice NA; Karlsson HK; Alessi DR
Biochem J; 2006 Jul; 397(1):223-31. PubMed ID: 16669787
[TBL] [Abstract][Full Text] [Related]
3. Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.
Elvers KT; Lipka-Lloyd M; Trueman RC; Bax BD; Mehellou Y
Chembiochem; 2022 Jan; 23(1):e202100441. PubMed ID: 34726826
[TBL] [Abstract][Full Text] [Related]
4. The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.
Alessi DR; Zhang J; Khanna A; Hochdörfer T; Shang Y; Kahle KT
Sci Signal; 2014 Jul; 7(334):re3. PubMed ID: 25028718
[TBL] [Abstract][Full Text] [Related]
5. WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
Thomson MN; Cuevas CA; Bewarder TM; Dittmayer C; Miller LN; Si J; Cornelius RJ; Su XT; Yang CL; McCormick JA; Hadchouel J; Ellison DH; Bachmann S; Mutig K
Am J Physiol Renal Physiol; 2020 Jan; 318(1):F216-F228. PubMed ID: 31736353
[TBL] [Abstract][Full Text] [Related]
6. A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.
Ponce-Coria J; Markadieu N; Austin TM; Flammang L; Rios K; Welling PA; Delpire E
J Biol Chem; 2014 Jun; 289(25):17680-8. PubMed ID: 24811174
[TBL] [Abstract][Full Text] [Related]
7. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
Thastrup JO; Rafiqi FH; Vitari AC; Pozo-Guisado E; Deak M; Mehellou Y; Alessi DR
Biochem J; 2012 Jan; 441(1):325-37. PubMed ID: 22032326
[TBL] [Abstract][Full Text] [Related]
8. WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
Moriguchi T; Urushiyama S; Hisamoto N; Iemura S; Uchida S; Natsume T; Matsumoto K; Shibuya H
J Biol Chem; 2005 Dec; 280(52):42685-93. PubMed ID: 16263722
[TBL] [Abstract][Full Text] [Related]
9. Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice.
Nishida H; Sohara E; Nomura N; Chiga M; Alessi DR; Rai T; Sasaki S; Uchida S
Hypertension; 2012 Oct; 60(4):981-90. PubMed ID: 22949526
[TBL] [Abstract][Full Text] [Related]
10. OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant.
Taylor CA; An SW; Kankanamalage SG; Stippec S; Earnest S; Trivedi AT; Yang JZ; Mirzaei H; Huang CL; Cobb MH
Proc Natl Acad Sci U S A; 2018 Apr; 115(15):3840-3845. PubMed ID: 29581290
[TBL] [Abstract][Full Text] [Related]
11. WNK pathways in cancer signaling networks.
Gallolu Kankanamalage S; Karra AS; Cobb MH
Cell Commun Signal; 2018 Nov; 16(1):72. PubMed ID: 30390653
[TBL] [Abstract][Full Text] [Related]
12. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.
de Los Heros P; Alessi DR; Gourlay R; Campbell DG; Deak M; Macartney TJ; Kahle KT; Zhang J
Biochem J; 2014 Mar; 458(3):559-73. PubMed ID: 24393035
[TBL] [Abstract][Full Text] [Related]
13. Targeting the WNK-SPAK/OSR1 Pathway and Cation-Chloride Cotransporters for the Therapy of Stroke.
Josiah SS; Meor Azlan NF; Zhang J
Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33513812
[TBL] [Abstract][Full Text] [Related]
14. WNK-SPAK/OSR1-NCC kinase signaling pathway as a novel target for the treatment of salt-sensitive hypertension.
Brown A; Meor Azlan NF; Wu Z; Zhang J
Acta Pharmacol Sin; 2021 Apr; 42(4):508-517. PubMed ID: 32724175
[TBL] [Abstract][Full Text] [Related]
15. Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.
Sengupta S; Tu SW; Wedin K; Earnest S; Stippec S; Luby-Phelps K; Cobb MH
J Biol Chem; 2012 Nov; 287(45):37868-79. PubMed ID: 22989884
[TBL] [Abstract][Full Text] [Related]
16. Molecular Mechanism of Inhibiting WNK Binding to OSR1 by Targeting the Allosteric Pocket of the OSR1-CCT Domain with Potential Antihypertensive Inhibitors: An
Jonniya NA; Zhang J; Kar P
J Phys Chem B; 2021 Aug; 125(32):9115-9129. PubMed ID: 34369793
[TBL] [Abstract][Full Text] [Related]
17. The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.
Vitari AC; Deak M; Morrice NA; Alessi DR
Biochem J; 2005 Oct; 391(Pt 1):17-24. PubMed ID: 16083423
[TBL] [Abstract][Full Text] [Related]
18. Physiological Processes Modulated by the Chloride-Sensitive WNK-SPAK/OSR1 Kinase Signaling Pathway and the Cation-Coupled Chloride Cotransporters.
Murillo-de-Ozores AR; Chávez-Canales M; de Los Heros P; Gamba G; Castañeda-Bueno M
Front Physiol; 2020; 11():585907. PubMed ID: 33192599
[TBL] [Abstract][Full Text] [Related]
19. Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses.
Vorontsova I; Lam L; Delpire E; Lim J; Donaldson P
Invest Ophthalmol Vis Sci; 2014 Dec; 56(1):310-21. PubMed ID: 25515571
[TBL] [Abstract][Full Text] [Related]
20. Structure Prediction of SPAK C-terminal Domain and Analysis of its Binding to RFXV/I Motifs by Homology Modelling, Docking and Molecular Dynamics Simulation Studies.
Alamri MA; Alafnan AD; Afzal O; Alabbas AB; Alqahtani SM
Curr Comput Aided Drug Des; 2021; 17(5):666-675. PubMed ID: 32652921
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
