BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 34314419)

  • 1. Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells.
    Strittmatter BG; Jerde TJ; Hollenhorst PC
    PLoS Genet; 2021 Jul; 17(7):e1009708. PubMed ID: 34314419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation.
    Kedage V; Strittmatter BG; Dausinas PB; Hollenhorst PC
    J Biol Chem; 2017 Oct; 292(42):17225-17235. PubMed ID: 28887309
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression.
    Henderson V; Smith B; Burton LJ; Randle D; Morris M; Odero-Marah VA
    Cell Adh Migr; 2015; 9(4):255-64. PubMed ID: 26207671
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation.
    Selvaraj N; Budka JA; Ferris MW; Jerde TJ; Hollenhorst PC
    Mol Cancer; 2014 Mar; 13():61. PubMed ID: 24642271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
    Mao N; Gao D; Hu W; Gadal S; Hieronymus H; Wang S; Lee YS; Sullivan P; Zhang Z; Choi D; Rosen N; Sawyers CL; Gopalan A; Chen Y; Carver BS
    Cancer Res; 2020 Apr; 80(7):1428-1437. PubMed ID: 32015092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
    Sandoval GJ; Pulice JL; Pakula H; Schenone M; Takeda DY; Pop M; Boulay G; Williamson KE; McBride MJ; Pan J; St Pierre R; Hartman E; Garraway LA; Carr SA; Rivera MN; Li Z; Ronco L; Hahn WC; Kadoch C
    Mol Cell; 2018 Aug; 71(4):554-566.e7. PubMed ID: 30078722
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.
    Gan Y; Shi C; Inge L; Hibner M; Balducci J; Huang Y
    Oncogene; 2010 Sep; 29(35):4947-58. PubMed ID: 20562913
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence.
    Fang L; Li D; Yin J; Pan H; Ye H; Bowman J; Capaldo B; Kelly K
    Cancer Gene Ther; 2022 Oct; 29(10):1463-1476. PubMed ID: 35393570
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells.
    Selvaraj N; Kedage V; Hollenhorst PC
    Cell Commun Signal; 2015 Feb; 13():12. PubMed ID: 25885538
    [TBL] [Abstract][Full Text] [Related]  

  • 10. EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer.
    Zoma M; Curti L; Shinde D; Albino D; Mitra A; Sgrignani J; Mapelli SN; Sandrini G; Civenni G; Merulla J; Chiorino G; Kunderfranco P; Cacciatore A; Kokanovic A; Rinaldi A; Cavalli A; Catapano CV; Carbone GM
    Nat Commun; 2021 Jul; 12(1):4147. PubMed ID: 34230470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes.
    Mao N; Gao D; Hu W; Hieronymus H; Wang S; Lee YS; Lee C; Choi D; Gopalan A; Chen Y; Carver BS
    Mol Cancer Ther; 2019 Sep; 18(9):1577-1586. PubMed ID: 31296553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling to increase SLUG expression in prostate cancer.
    Ding G; Fang J; Tong S; Qu L; Jiang H; Ding Q; Liu J
    Prostate; 2015 Jun; 75(9):957-68. PubMed ID: 25728945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ERG-Mediated Coregulator Complex Formation Maintains Androgen Receptor Signaling in Prostate Cancer.
    Shah N; Kesten N; Font-Tello A; Chang MEK; Vadhi R; Lim K; Flory MR; Cejas P; Mohammed H; Long HW; Brown M
    Cancer Res; 2020 Nov; 80(21):4612-4619. PubMed ID: 32934023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells.
    Ratz L; Laible M; Kacprzyk LA; Wittig-Blaich SM; Tolstov Y; Duensing S; Altevogt P; Klauck SM; Sültmann H
    Oncotarget; 2017 Apr; 8(15):25115-25130. PubMed ID: 28445989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells.
    Zong Y; Xin L; Goldstein AS; Lawson DA; Teitell MA; Witte ON
    Proc Natl Acad Sci U S A; 2009 Jul; 106(30):12465-70. PubMed ID: 19592505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF; Chan KK; Grills C; Murray JT; Platt-Higgins A; Eldin OS; O'Byrne K; Janne P; Fennell DA; Johnston PG; Rudland PS; El-Tanani M
    Clin Cancer Res; 2012 Jan; 18(2):380-91. PubMed ID: 22090358
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ERG-SOX4 interaction promotes epithelial-mesenchymal transition in prostate cancer cells.
    Wang L; Li Y; Yang X; Yuan H; Li X; Qi M; Chang YW; Wang C; Fu W; Yang M; Zhang J; Han B
    Prostate; 2014 May; 74(6):647-58. PubMed ID: 24435928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. miR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT.
    Kao CJ; Martiniez A; Shi XB; Yang J; Evans CP; Dobi A; deVere White RW; Kung HJ
    Oncogene; 2014 May; 33(19):2495-503. PubMed ID: 23728339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma.
    Xu S; Yi XM; Tang CP; Ge JP; Zhang ZY; Zhou WQ
    Oncol Rep; 2016 Jul; 36(1):10-22. PubMed ID: 27176634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion.
    Yang Y; Blee AM; Wang D; An J; Pan Y; Yan Y; Ma T; He Y; Dugdale J; Hou X; Zhang J; Weroha SJ; Zhu WG; Wang YA; DePinho RA; Xu W; Huang H
    Cancer Res; 2017 Dec; 77(23):6524-6537. PubMed ID: 28986382
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.