These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 34319715)

  • 1. Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout.
    Al-Amin RA; Gallant CJ; Muthelo PM; Landegren U
    Anal Chem; 2021 Aug; 93(31):10999-11009. PubMed ID: 34319715
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.
    Sanchez TW; Ronzetti MH; Owens AE; Antony M; Voss T; Wallgren E; Talley D; Balakrishnan K; Leyes Porello SE; Rai G; Marugan JJ; Michael SG; Baljinnyam B; Southall N; Simeonov A; Henderson MJ
    ACS Chem Biol; 2022 Sep; 17(9):2471-2482. PubMed ID: 36049119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies.
    Martinez Molina D; Nordlund P
    Annu Rev Pharmacol Toxicol; 2016; 56():141-61. PubMed ID: 26566155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.
    McNulty DE; Bonnette WG; Qi H; Wang L; Ho TF; Waszkiewicz A; Kallal LA; Nagarajan RP; Stern M; Quinn AM; Creasy CL; Su DS; Graves AP; Annan RS; Sweitzer SM; Holbert MA
    SLAS Discov; 2018 Jan; 23(1):34-46. PubMed ID: 28957646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Drug Target Engagement Using Coupled Cellular Thermal Shift Assay-Acoustic Reverse-Phase Protein Array.
    Herledan A; Andres M; Lejeune-Dodge A; Leroux F; Biela A; Piveteau C; Warenghem S; Couturier C; Deprez B; Deprez-Poulain R
    SLAS Discov; 2020 Feb; 25(2):207-214. PubMed ID: 31885312
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mass spectrometry-based Cellular Thermal Shift Assay (CETSA®) for target deconvolution in phenotypic drug discovery.
    Friman T
    Bioorg Med Chem; 2020 Jan; 28(1):115174. PubMed ID: 31767405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery.
    Henderson MJ; Holbert MA; Simeonov A; Kallal LA
    SLAS Discov; 2020 Feb; 25(2):137-147. PubMed ID: 31566060
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA).
    Dai L; Prabhu N; Yu LY; Bacanu S; Ramos AD; Nordlund P
    Annu Rev Biochem; 2019 Jun; 88():383-408. PubMed ID: 30939043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CETSA: a target engagement assay with potential to transform drug discovery.
    Jensen AJ; Martinez Molina D; Lundbäck T
    Future Med Chem; 2015; 7(8):975-8. PubMed ID: 26062395
    [No Abstract]   [Full Text] [Related]  

  • 10. Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels.
    Reckzeh ES; Brockmeyer A; Metz M; Waldmann H; Janning P
    Methods Mol Biol; 2019; 1888():73-98. PubMed ID: 30519941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell Density Affects the Detection of Chk1 Target Engagement by the Selective Inhibitor V158411.
    Geneste CC; Massey AJ
    SLAS Discov; 2018 Feb; 23(2):144-153. PubMed ID: 29048945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1.
    Shaw J; Dale I; Hemsley P; Leach L; Dekki N; Orme JP; Talbot V; Narvaez AJ; Bista M; Martinez Molina D; Dabrowski M; Main MJ; Gianni D
    SLAS Discov; 2019 Feb; 24(2):121-132. PubMed ID: 30543471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The cellular thermal shift assay for evaluating drug target interactions in cells.
    Jafari R; Almqvist H; Axelsson H; Ignatushchenko M; Lundbäck T; Nordlund P; Martinez Molina D
    Nat Protoc; 2014 Sep; 9(9):2100-22. PubMed ID: 25101824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA).
    Hengst JA; Dick TE; Smith CD; Yun JK
    Cancer Biol Ther; 2020 Sep; 21(9):841-852. PubMed ID: 32835586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Perspective on CETSA Literature: Toward More Quantitative Data Interpretation.
    Seashore-Ludlow B; Axelsson H; Lundbäck T
    SLAS Discov; 2020 Feb; 25(2):118-126. PubMed ID: 31665966
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High throughput screening of 0.5 million compounds against CRAF using Alpha CETSA
    Rowlands H; Tschapalda K; Blackett C; Ivanov D; Plant D; Shaw J; Thomas A; Packer M; Arnold L; Holdgate GA
    SLAS Discov; 2023 Apr; 28(3):102-110. PubMed ID: 36736830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.
    Martinez Molina D; Jafari R; Ignatushchenko M; Seki T; Larsson EA; Dan C; Sreekumar L; Cao Y; Nordlund P
    Science; 2013 Jul; 341(6141):84-7. PubMed ID: 23828940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Current Advances in CETSA.
    Tolvanen TA
    Front Mol Biosci; 2022; 9():866764. PubMed ID: 35755818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-Throughput Cellular Thermal Shift Assay Using Acoustic Transfer of Protein Lysates.
    Owens AE; Iannotti MJ; Sanchez TW; Voss T; Kapoor A; Hall MD; Marugan JJ; Michael S; Southall N; Henderson MJ
    ACS Chem Biol; 2022 Feb; 17(2):322-330. PubMed ID: 35119255
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase.
    Martinez NJ; Asawa RR; Cyr MG; Zakharov A; Urban DJ; Roth JS; Wallgren E; Klumpp-Thomas C; Coussens NP; Rai G; Yang SM; Hall MD; Marugan JJ; Simeonov A; Henderson MJ
    Sci Rep; 2018 Jun; 8(1):9472. PubMed ID: 29930256
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.