205 related articles for article (PubMed ID: 34321240)
21. Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations.
Intlekofer AM; Shih AH; Wang B; Nazir A; Rustenburg AS; Albanese SK; Patel M; Famulare C; Correa FM; Takemoto N; Durani V; Liu H; Taylor J; Farnoud N; Papaemmanuil E; Cross JR; Tallman MS; Arcila ME; Roshal M; Petsko GA; Wu B; Choe S; Konteatis ZD; Biller SA; Chodera JD; Thompson CB; Levine RL; Stein EM
Nature; 2018 Jul; 559(7712):125-129. PubMed ID: 29950729
[TBL] [Abstract][Full Text] [Related]
22. Mir142 loss unlocks IDH2
Marshall A; Kasturiarachchi J; Datta P; Guo Y; Deltcheva E; James C; Brown J; May G; Anandagoda N; Jackson I; Howard JK; Ghazaly E; Brooks S; Khwaja A; Araki M; Araki K; Linch D; Lord GM; Enver T; Nimmo R
Sci Rep; 2020 Nov; 10(1):19390. PubMed ID: 33173219
[TBL] [Abstract][Full Text] [Related]
23. Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.
Pineault N; Buske C; Feuring-Buske M; Abramovich C; Rosten P; Hogge DE; Aplan PD; Humphries RK
Blood; 2003 Jun; 101(11):4529-38. PubMed ID: 12543865
[TBL] [Abstract][Full Text] [Related]
24. NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.
Xu H; Valerio DG; Eisold ME; Sinha A; Koche RP; Hu W; Chen CW; Chu SH; Brien GL; Park CY; Hsieh JJ; Ernst P; Armstrong SA
Cancer Cell; 2016 Dec; 30(6):863-878. PubMed ID: 27889185
[TBL] [Abstract][Full Text] [Related]
25. Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.
Gough SM; Chung YJ; Aplan PD
PLoS One; 2012; 7(5):e36876. PubMed ID: 22606303
[TBL] [Abstract][Full Text] [Related]
26. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.
Chen C; Liu Y; Lu C; Cross JR; Morris JP; Shroff AS; Ward PS; Bradner JE; Thompson C; Lowe SW
Genes Dev; 2013 Sep; 27(18):1974-85. PubMed ID: 24065765
[TBL] [Abstract][Full Text] [Related]
27. NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men.
Slape C; Lin YW; Hartung H; Zhang Z; Wolff L; Aplan PD
J Natl Cancer Inst Monogr; 2008; (39):64-8. PubMed ID: 18648006
[TBL] [Abstract][Full Text] [Related]
28. Gene expression profiling of precursor T-cell lymphoblastic leukemia/lymphoma identifies oncogenic pathways that are potential therapeutic targets.
Lin YW; Aplan PD
Leukemia; 2007 Jun; 21(6):1276-84. PubMed ID: 17429429
[TBL] [Abstract][Full Text] [Related]
29. SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS.
Chen BY; Song J; Hu CL; Chen SB; Zhang Q; Xu CH; Wu JC; Hou D; Sun M; Zhang YL; Liu N; Yu PC; Liu P; Zong LJ; Zhang JY; Dai RF; Lan F; Huang QH; Zhang SJ; Nimer SD; Chen Z; Chen SJ; Sun XJ; Wang L
Blood; 2020 Jun; 135(25):2271-2285. PubMed ID: 32202636
[TBL] [Abstract][Full Text] [Related]
30. IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders.
Zou Y; Zeng Y; Zhang DF; Zou SH; Cheng YF; Yao YG
Biochem Biophys Res Commun; 2010 Nov; 402(2):378-83. PubMed ID: 20946881
[TBL] [Abstract][Full Text] [Related]
31. AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic
Yen K; Travins J; Wang F; David MD; Artin E; Straley K; Padyana A; Gross S; DeLaBarre B; Tobin E; Chen Y; Nagaraja R; Choe S; Jin L; Konteatis Z; Cianchetta G; Saunders JO; Salituro FG; Quivoron C; Opolon P; Bawa O; Saada V; Paci A; Broutin S; Bernard OA; de Botton S; Marteyn BS; Pilichowska M; Xu Y; Fang C; Jiang F; Wei W; Jin S; Silverman L; Liu W; Yang H; Dang L; Dorsch M; Penard-Lacronique V; Biller SA; Su SM
Cancer Discov; 2017 May; 7(5):478-493. PubMed ID: 28193778
[TBL] [Abstract][Full Text] [Related]
32. PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.
Cheng X; Byrne M; Brown KD; Konopleva MY; Kornblau SM; Bennett RL; May WS
Blood; 2015 Sep; 126(13):1585-94. PubMed ID: 26202421
[TBL] [Abstract][Full Text] [Related]
33. A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.
Yin M; Baslan T; Walker RL; Zhu YJ; Freeland A; Matsukawa T; Sridharan S; Nussenzweig A; Pruitt SC; Lowe SW; Meltzer PS; Aplan PD
JCI Insight; 2019 Dec; 4(23):. PubMed ID: 31622281
[TBL] [Abstract][Full Text] [Related]
34. IDH1 and IDH2 mutations in pediatric acute leukemia.
Andersson AK; Miller DW; Lynch JA; Lemoff AS; Cai Z; Pounds SB; Radtke I; Yan B; Schuetz JD; Rubnitz JE; Ribeiro RC; Raimondi SC; Zhang J; Mullighan CG; Shurtleff SA; Schulman BA; Downing JR
Leukemia; 2011 Oct; 25(10):1570-7. PubMed ID: 21647154
[TBL] [Abstract][Full Text] [Related]
35. IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition.
Kernytsky A; Wang F; Hansen E; Schalm S; Straley K; Gliser C; Yang H; Travins J; Murray S; Dorsch M; Agresta S; Schenkein DP; Biller SA; Su SM; Liu W; Yen KE
Blood; 2015 Jan; 125(2):296-303. PubMed ID: 25398940
[TBL] [Abstract][Full Text] [Related]
36. Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia.
Ashraf S; Noguera NI; Di Giandomenico J; Zaza S; Hasan SK; Lo-Coco F
Ann Hematol; 2013 Oct; 92(10):1319-23. PubMed ID: 23949315
[TBL] [Abstract][Full Text] [Related]
37. [Analysis of IDH1 and IDH2 mutations in patients with acute myeloid leukemia].
Jia ZX; Zhou M; Chao HY; Lu XZ; Zhang R; Cen L; Xiao R; Jiang NK
Zhonghua Xue Ye Xue Za Zhi; 2012 May; 33(5):397-401. PubMed ID: 22781800
[TBL] [Abstract][Full Text] [Related]
38. Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities.
Cardin S; Bilodeau M; Roussy M; Aubert L; Milan T; Jouan L; Rouette A; Laramée L; Gendron P; Duchaine J; Decaluwe H; Spinella JF; Mourad S; Couture F; Sinnett D; Haddad É; Landry JR; Ma J; Humphries RK; Roux PP; Hébert J; Gruber TA; Wilhelm BT; Cellot S
Blood Adv; 2019 Nov; 3(21):3307-3321. PubMed ID: 31698461
[TBL] [Abstract][Full Text] [Related]
39. A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production.
Puthiyaveetil AG; Heid B; Reilly CM; HogenEsch H; Caudell DL
Exp Hematol; 2012 Aug; 40(8):622-33. PubMed ID: 22613470
[TBL] [Abstract][Full Text] [Related]
40. Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.
Zuurbier L; Gutierrez A; Mullighan CG; Canté-Barrett K; Gevaert AO; de Rooi J; Li Y; Smits WK; Buijs-Gladdines JG; Sonneveld E; Look AT; Horstmann M; Pieters R; Meijerink JP
Haematologica; 2014 Jan; 99(1):94-102. PubMed ID: 23975177
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
