197 related articles for article (PubMed ID: 34322387)
1. Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neuroblastoma Cells.
Gong B; Zhang J; Hua Z; Liu Z; Thiele CJ; Li Z
Front Oncol; 2021; 11():686898. PubMed ID: 34322387
[TBL] [Abstract][Full Text] [Related]
2. Corrigendum: Downregulation of ATXN3 enhances the sensitivity to AKT inhibitors (Perifosine or MK-2206), but decreases the sensitivity to chemotherapeutic drugs (etoposide or cisplatin) in neuroblastoma cells.
Gong B; Zhang J; Hua Z; Liu Z; Thiele CJ; Li Z
Front Oncol; 2022; 12():984514. PubMed ID: 35992874
[TBL] [Abstract][Full Text] [Related]
3. Perifosine-induced inhibition of Akt attenuates brain-derived neurotrophic factor/TrkB-induced chemoresistance in neuroblastoma in vivo.
Li Z; Oh DY; Nakamura K; Thiele CJ
Cancer; 2011 Dec; 117(23):5412-22. PubMed ID: 21590687
[TBL] [Abstract][Full Text] [Related]
4. Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death.
Li Z; Zhang J; Liu Z; Woo CW; Thiele CJ
Cell Death Differ; 2007 Feb; 14(2):318-26. PubMed ID: 16778834
[TBL] [Abstract][Full Text] [Related]
5. P53/PUMA are potential targets that mediate the protection of brain-derived neurotrophic factor (BDNF)/TrkB from etoposide-induced cell death in neuroblastoma (NB).
Hua Z; Zhan Y; Zhang S; Dong Y; Jiang M; Tan F; Liu Z; Thiele CJ; Li Z
Apoptosis; 2018 Aug; 23(7-8):408-419. PubMed ID: 29959561
[TBL] [Abstract][Full Text] [Related]
6. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
Nalluri S; Peirce SK; Tanos R; Abdella HA; Karmali D; Hogarty MD; Goldsmith KC
Cancer Biol Ther; 2015; 16(2):276-86. PubMed ID: 25756510
[TBL] [Abstract][Full Text] [Related]
7. Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways.
Nyåkern M; Cappellini A; Mantovani I; Martelli AM
Mol Cancer Ther; 2006 Jun; 5(6):1559-70. PubMed ID: 16818515
[TBL] [Abstract][Full Text] [Related]
8. Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis.
Dole MG; Jasty R; Cooper MJ; Thompson CB; Nuñez G; Castle VP
Cancer Res; 1995 Jun; 55(12):2576-82. PubMed ID: 7780971
[TBL] [Abstract][Full Text] [Related]
9. PI3K-Akt Signal Transduction Molecules Maybe Involved in Downregulation of Erythroblasts Apoptosis and Perifosine Increased Its Apoptosis in Chronic Mountain Sickness.
Zhao C; Li Z; Ji L; Ma J; Ge RL; Cui S
Med Sci Monit; 2017 Nov; 23():5637-5649. PubMed ID: 29176544
[TBL] [Abstract][Full Text] [Related]
10. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
[TBL] [Abstract][Full Text] [Related]
11. Combination of an allosteric Akt Inhibitor MK-2206 with etoposide or rapamycin enhances the antitumor growth effect in neuroblastoma.
Li Z; Yan S; Attayan N; Ramalingam S; Thiele CJ
Clin Cancer Res; 2012 Jul; 18(13):3603-15. PubMed ID: 22550167
[TBL] [Abstract][Full Text] [Related]
12. Select Bcl-2 antagonism restores chemotherapy sensitivity in high-risk neuroblastoma.
Tanos R; Karmali D; Nalluri S; Goldsmith KC
BMC Cancer; 2016 Feb; 16():97. PubMed ID: 26874859
[TBL] [Abstract][Full Text] [Related]
13. Expression of bcl-xL can confer a multidrug resistance phenotype.
Minn AJ; Rudin CM; Boise LH; Thompson CB
Blood; 1995 Sep; 86(5):1903-10. PubMed ID: 7655019
[TBL] [Abstract][Full Text] [Related]
14. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
[TBL] [Abstract][Full Text] [Related]
15. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
[TBL] [Abstract][Full Text] [Related]
16. Nitric Oxide Synthase Potentiates the Resistance of Cancer Cell Lines to Anticancer Chemotherapeutics.
Barnawi I; Hawsawi YM; Dash P; Oyouni AAA; Mustafa SK; Hussien NA; Al-Amer O; Alomar S; Mansour L
Anticancer Agents Med Chem; 2022; 22(7):1397-1406. PubMed ID: 34165414
[TBL] [Abstract][Full Text] [Related]
17. The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways.
Rahmani M; Anderson A; Habibi JR; Crabtree TR; Mayo M; Harada H; Ferreira-Gonzalez A; Dent P; Grant S
Blood; 2009 Nov; 114(20):4507-16. PubMed ID: 19773546
[TBL] [Abstract][Full Text] [Related]
18. PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.
Bender A; Opel D; Naumann I; Kappler R; Friedman L; von Schweinitz D; Debatin KM; Fulda S
Oncogene; 2011 Jan; 30(4):494-503. PubMed ID: 20856197
[TBL] [Abstract][Full Text] [Related]
19. Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins.
Hadjidaniel MD; Reynolds CP
Mol Cancer Ther; 2010 Dec; 9(12):3164-74. PubMed ID: 21159604
[TBL] [Abstract][Full Text] [Related]
20. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
