BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 34323119)

  • 1. Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling.
    Pal S; Nixon BR; Glennon MS; Shridhar P; Satterfield SL; Su YR; Becker JR
    J Am Heart Assoc; 2021 Aug; 10(15):e021768. PubMed ID: 34323119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy.
    Witjas-Paalberends ER; Piroddi N; Stam K; van Dijk SJ; Oliviera VS; Ferrara C; Scellini B; Hazebroek M; ten Cate FJ; van Slegtenhorst M; dos Remedios C; Niessen HW; Tesi C; Stienen GJ; Heymans S; Michels M; Poggesi C; van der Velden J
    Cardiovasc Res; 2013 Aug; 99(3):432-41. PubMed ID: 23674513
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development.
    Nixon BR; Williams AF; Glennon MS; de Feria AE; Sebag SC; Baldwin HS; Becker JR
    JCI Insight; 2017 Feb; 2(4):e90656. PubMed ID: 28239655
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MDM2 Regulation of HIF Signaling Causes Microvascular Dysfunction in Hypertrophic Cardiomyopathy.
    Shridhar P; Glennon MS; Pal S; Waldron CJ; Chetkof EJ; Basak P; Clavere NG; Banerjee D; Gingras S; Becker JR
    Circulation; 2023 Dec; 148(23):1870-1886. PubMed ID: 37886847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
    Sequeira V; Wijnker PJ; Nijenkamp LL; Kuster DW; Najafi A; Witjas-Paalberends ER; Regan JA; Boontje N; Ten Cate FJ; Germans T; Carrier L; Sadayappan S; van Slegtenhorst MA; Zaremba R; Foster DB; Murphy AM; Poggesi C; Dos Remedios C; Stienen GJ; Ho CY; Michels M; van der Velden J
    Circ Res; 2013 May; 112(11):1491-505. PubMed ID: 23508784
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction.
    van Dijk SJ; Dooijes D; dos Remedios C; Michels M; Lamers JM; Winegrad S; Schlossarek S; Carrier L; ten Cate FJ; Stienen GJ; van der Velden J
    Circulation; 2009 Mar; 119(11):1473-83. PubMed ID: 19273718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning.
    Keul P; van Borren MM; Ghanem A; Müller FU; Baartscheer A; Verkerk AO; Stümpel F; Schulte JS; Hamdani N; Linke WA; van Loenen P; Matus M; Schmitz W; Stypmann J; Tiemann K; Ravesloot JH; Alewijnse AE; Hermann S; Spijkers LJ; Hiller KH; Herr D; Heusch G; Schäfers M; Peters SL; Chun J; Levkau B
    J Am Heart Assoc; 2016 May; 5(5):. PubMed ID: 27207969
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue.
    Wijnker PJM; van der Velden J
    Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165774. PubMed ID: 32217077
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations.
    Olivotto I; Girolami F; Sciagrà R; Ackerman MJ; Sotgia B; Bos JM; Nistri S; Sgalambro A; Grifoni C; Torricelli F; Camici PG; Cecchi F
    J Am Coll Cardiol; 2011 Aug; 58(8):839-48. PubMed ID: 21835320
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prevalence and Phenotypic Expression of Mutations in the MYH7, MYBPC3 and TNNT2 Genes in Families with Hypertrophic Cardiomyopathy in the South of Brazil: A Cross-Sectional Study.
    Mattos BP; Scolari FL; Torres MA; Simon L; Freitas VC; Giugliani R; Matte Ú
    Arq Bras Cardiol; 2016 Sep; 107(3):257-265. PubMed ID: 27737317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes.
    Monteiro da Rocha A; Guerrero-Serna G; Helms A; Luzod C; Mironov S; Russell M; Jalife J; Day SM; Smith GD; Herron TJ
    J Mol Cell Cardiol; 2016 Oct; 99():197-206. PubMed ID: 27620334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sarcomere mutations in cardiomyopathy with left ventricular hypertrabeculation.
    Dellefave LM; Pytel P; Mewborn S; Mora B; Guris DL; Fedson S; Waggoner D; Moskowitz I; McNally EM
    Circ Cardiovasc Genet; 2009 Oct; 2(5):442-9. PubMed ID: 20031619
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in sarcomere protein genes in left ventricular noncompaction.
    Klaassen S; Probst S; Oechslin E; Gerull B; Krings G; Schuler P; Greutmann M; Hürlimann D; Yegitbasi M; Pons L; Gramlich M; Drenckhahn JD; Heuser A; Berger F; Jenni R; Thierfelder L
    Circulation; 2008 Jun; 117(22):2893-901. PubMed ID: 18506004
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.
    Najafi A; Sequeira V; Helmes M; Bollen IA; Goebel M; Regan JA; Carrier L; Kuster DW; Van Der Velden J
    Cardiovasc Res; 2016 May; 110(2):200-14. PubMed ID: 26825555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential contributions of sarcomere and mitochondria-related multigene variants to the endophenotype of hypertrophic cardiomyopathy.
    Chung H; Kim Y; Cho SM; Lee HJ; Park CH; Kim JY; Lee SH; Min PK; Yoon YW; Lee BK; Kim WS; Hong BK; Kim TH; Rim SJ; Kwon HM; Choi EY; Lee KA
    Mitochondrion; 2020 Jul; 53():48-56. PubMed ID: 32380161
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unexpectedly low mutation rates in beta-myosin heavy chain and cardiac myosin binding protein genes in Italian patients with hypertrophic cardiomyopathy.
    Roncarati R; Latronico MV; Musumeci B; Aurino S; Torella A; Bang ML; Jotti GS; Puca AA; Volpe M; Nigro V; Autore C; Condorelli G
    J Cell Physiol; 2011 Nov; 226(11):2894-900. PubMed ID: 21302287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice.
    Flenner F; Geertz B; Reischmann-Düsener S; Weinberger F; Eschenhagen T; Carrier L; Friedrich FW
    J Physiol; 2017 Jun; 595(12):3987-3999. PubMed ID: 28090637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The novel cardiac z-disc protein CEFIP regulates cardiomyocyte hypertrophy by modulating calcineurin signaling.
    Dierck F; Kuhn C; Rohr C; Hille S; Braune J; Sossalla S; Molt S; van der Ven PFM; Fürst DO; Frey N
    J Biol Chem; 2017 Sep; 292(37):15180-15191. PubMed ID: 28717008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Moving beyond simple answers to complex disorders in sarcomeric cardiomyopathies: the role of integrated systems.
    Deranek AE; Klass MM; Tardiff JC
    Pflugers Arch; 2019 May; 471(5):661-671. PubMed ID: 30848350
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.
    Ferrantini C; Coppini R; Pioner JM; Gentile F; Tosi B; Mazzoni L; Scellini B; Piroddi N; Laurino A; Santini L; Spinelli V; Sacconi L; De Tombe P; Moore R; Tardiff J; Mugelli A; Olivotto I; Cerbai E; Tesi C; Poggesi C
    J Am Heart Assoc; 2017 Jul; 6(7):. PubMed ID: 28735292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.