These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 34323246)

  • 1. Inhibition of off-target cleavage by RNase H using an artificial cationic oligosaccharide.
    Hara RI; Wada T
    Org Biomol Chem; 2021 Aug; 19(31):6865-6870. PubMed ID: 34323246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Artificial cationic oligosaccharides for heteroduplex oligonucleotide-type drugs.
    Hara RI; Hisada Y; Maeda Y; Yokota T; Wada T
    Sci Rep; 2018 Mar; 8(1):4323. PubMed ID: 29531343
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids.
    Lima WF; Crooke ST
    Biochemistry; 1997 Jan; 36(2):390-8. PubMed ID: 9003192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNase H sequence preferences influence antisense oligonucleotide efficiency.
    Kielpinski LJ; Hagedorn PH; Lindow M; Vinther J
    Nucleic Acids Res; 2017 Dec; 45(22):12932-12944. PubMed ID: 29126318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gapmer Antisense Oligonucleotides Containing 2',3'-Dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-d-lyxofuranosyl Nucleotides Display Site-Specific RNase H Cleavage and Induce Gene Silencing.
    Danielsen MB; Lou C; Lisowiec-Wachnicka J; Pasternak A; Jørgensen PT; Wengel J
    Chemistry; 2020 Jan; 26(6):1368-1379. PubMed ID: 31682037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent and selective inhibition of gene expression by an antisense heptanucleotide.
    Wagner RW; Matteucci MD; Grant D; Huang T; Froehler BC
    Nat Biotechnol; 1996 Jul; 14(7):840-4. PubMed ID: 9631007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis.
    Vickers TA; Koo S; Bennett CF; Crooke ST; Dean NM; Baker BF
    J Biol Chem; 2003 Feb; 278(9):7108-18. PubMed ID: 12500975
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Is irrelevant cleavage the price of antisense efficacy?
    Stein CA
    Pharmacol Ther; 2000 Mar; 85(3):231-6. PubMed ID: 10739877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2'-O-methylated 2-5A-antisense oligonucleotides.
    Cramer H; Player MR; Torrence PF
    Bioorg Med Chem Lett; 1999 Apr; 9(7):1049-54. PubMed ID: 10230638
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity.
    Lima WF; Mohan V; Crooke ST
    J Biol Chem; 1997 Jul; 272(29):18191-9. PubMed ID: 9218455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxyribose nucleotides.
    Lok CN; Viazovkina E; Min KL; Nagy E; Wilds CJ; Damha MJ; Parniak MA
    Biochemistry; 2002 Mar; 41(10):3457-67. PubMed ID: 11876654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oligonucleotides comprised of alternating 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides and D-2'-deoxyribonucleosides (2'F-ANA/DNA 'altimers') induce efficient RNA cleavage mediated by RNase H.
    Min KL; Viazovkina E; Galarneau A; Parniak MA; Damha MJ
    Bioorg Med Chem Lett; 2002 Sep; 12(18):2651-4. PubMed ID: 12182880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carba-LNA-5MeC/A/G/T modified oligos show nucleobase-specific modulation of 3'-exonuclease activity, thermodynamic stability, RNA selectivity, and RNase H elicitation: synthesis and biochemistry.
    Upadhayaya R; Deshpande SG; Li Q; Kardile RA; Sayyed AY; Kshirsagar EK; Salunke RV; Dixit SS; Zhou C; Földesi A; Chattopadhyaya J
    J Org Chem; 2011 Jun; 76(11):4408-31. PubMed ID: 21500818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. XRN2 is required for the degradation of target RNAs by RNase H1-dependent antisense oligonucleotides.
    Hori S; Yamamoto T; Obika S
    Biochem Biophys Res Commun; 2015 Aug; 464(2):506-11. PubMed ID: 26159921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. How RNase HI (Escherichia coli) promoted site-selective hydrolysis works on RNA in duplex with carba-LNA and LNA substituted antisense strands in an antisense strategy context?
    Plashkevych O; Li Q; Chattopadhyaya J
    Mol Biosyst; 2017 May; 13(5):921-938. PubMed ID: 28352859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorothioate oligonucleotides block reverse transcription by the Rnase H activity associated with the HIV-1 polymerase.
    Hatta T; Takai K; Yokoyama S; Nakashima H; Yamamoto N; Takaku H
    Biochem Biophys Res Commun; 1995 Jun; 211(3):1041-6. PubMed ID: 7541196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides.
    Boiziau C; Thuong NT; Toulmé JJ
    Proc Natl Acad Sci U S A; 1992 Jan; 89(2):768-72. PubMed ID: 1370586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assay for evaluating ribonuclease H-mediated degradation of RNA-antisense oligonucleotide duplexes.
    Galarneau A; Min KL; Mangos MM; Damha MJ
    Methods Mol Biol; 2005; 288():65-80. PubMed ID: 15333898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide.
    Flanagan WM; Wagner RW; Grant D; Lin KY; Matteucci MD
    Nat Biotechnol; 1999 Jan; 17(1):48-52. PubMed ID: 9920268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures.
    Giles RV; Tidd DM
    Nucleic Acids Res; 1992 Feb; 20(4):763-70. PubMed ID: 1371864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.