263 related articles for article (PubMed ID: 34326423)
1. A novel orally active HDAC6 inhibitor T-518 shows a therapeutic potential for Alzheimer's disease and tauopathy in mice.
Onishi T; Maeda R; Terada M; Sato S; Fujii T; Ito M; Hashikami K; Kawamoto T; Tanaka M
Sci Rep; 2021 Jul; 11(1):15423. PubMed ID: 34326423
[TBL] [Abstract][Full Text] [Related]
2. A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
Zhang B; Yao Y; Cornec AS; Oukoloff K; James MJ; Koivula P; Trojanowski JQ; Smith AB; Lee VM; Ballatore C; Brunden KR
Mol Neurodegener; 2018 Nov; 13(1):59. PubMed ID: 30404654
[TBL] [Abstract][Full Text] [Related]
3. An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.
Carlomagno Y; Chung DC; Yue M; Castanedes-Casey M; Madden BJ; Dunmore J; Tong J; DeTure M; Dickson DW; Petrucelli L; Cook C
J Biol Chem; 2017 Sep; 292(37):15277-15286. PubMed ID: 28760828
[TBL] [Abstract][Full Text] [Related]
4. Increased acetylation of microtubules rescues human tau-induced microtubule defects and neuromuscular junction abnormalities in
Mao CX; Wen X; Jin S; Zhang YQ
Dis Model Mech; 2017 Oct; 10(10):1245-1252. PubMed ID: 28819043
[TBL] [Abstract][Full Text] [Related]
5. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition.
Bertels Z; Singh H; Dripps I; Siegersma K; Tipton AF; Witkowski WD; Sheets Z; Shah P; Conway C; Mangutov E; Ao M; Petukhova V; Karumudi B; Petukhov PA; Baca SM; Rasenick MM; Pradhan AA
Elife; 2021 Apr; 10():. PubMed ID: 33856345
[TBL] [Abstract][Full Text] [Related]
6. Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury.
Zheng Z; Zhou Y; Ye L; Lu Q; Zhang K; Zhang J; Xie L; Wu Y; Xu K; Zhang H; Xiao J
Exp Neurol; 2020 Feb; 324():113138. PubMed ID: 31794745
[TBL] [Abstract][Full Text] [Related]
7. Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport.
Choi H; Kim HJ; Kim J; Kim S; Yang J; Lee W; Park Y; Hyeon SJ; Lee DS; Ryu H; Chung J; Mook-Jung I
Mol Neurodegener; 2017 Feb; 12(1):23. PubMed ID: 28241840
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Van Helleputte L; Kater M; Cook DP; Eykens C; Rossaert E; Haeck W; Jaspers T; Geens N; Vanden Berghe P; Gysemans C; Mathieu C; Robberecht W; Van Damme P; Cavaletti G; Jarpe M; Van Den Bosch L
Neurobiol Dis; 2018 Mar; 111():59-69. PubMed ID: 29197621
[TBL] [Abstract][Full Text] [Related]
9. Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.
Kalinski AL; Kar AN; Craver J; Tosolini AP; Sleigh JN; Lee SJ; Hawthorne A; Brito-Vargas P; Miller-Randolph S; Passino R; Shi L; Wong VSC; Picci C; Smith DS; Willis DE; Havton LA; Schiavo G; Giger RJ; Langley B; Twiss JL
J Cell Biol; 2019 Jun; 218(6):1871-1890. PubMed ID: 31068376
[TBL] [Abstract][Full Text] [Related]
10. HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila.
Xiong Y; Zhao K; Wu J; Xu Z; Jin S; Zhang YQ
Proc Natl Acad Sci U S A; 2013 Mar; 110(12):4604-9. PubMed ID: 23487739
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010-2020).
Li Y; Sang S; Ren W; Pei Y; Bian Y; Chen Y; Sun H
Eur J Med Chem; 2021 Dec; 226():113874. PubMed ID: 34619465
[TBL] [Abstract][Full Text] [Related]
12. Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.
Adalbert R; Kaieda A; Antoniou C; Loreto A; Yang X; Gilley J; Hoshino T; Uga K; Makhija MT; Coleman MP
ACS Chem Neurosci; 2020 Feb; 11(3):258-267. PubMed ID: 31845794
[TBL] [Abstract][Full Text] [Related]
13. Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition.
Sreenivasmurthy SG; Iyaswamy A; Krishnamoorthi S; Senapati S; Malampati S; Zhu Z; Su CF; Liu J; Guan XJ; Tong BC; Cheung KH; Tan JQ; Lu JH; Durairajan SSK; Song JX; Li M
Phytomedicine; 2022 Feb; 96():153887. PubMed ID: 34936968
[TBL] [Abstract][Full Text] [Related]
14. An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
Trzeciakiewicz H; Ajit D; Tseng JH; Chen Y; Ajit A; Tabassum Z; Lobrovich R; Peterson C; Riddick NV; Itano MS; Tripathy A; Moy SS; Lee VMY; Trojanowski JQ; Irwin DJ; Cohen TJ
Nat Commun; 2020 Nov; 11(1):5522. PubMed ID: 33139698
[TBL] [Abstract][Full Text] [Related]
15. HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions.
Osseni A; Ravel-Chapuis A; Thomas JL; Gache V; Schaeffer L; Jasmin BJ
J Cell Biol; 2020 Aug; 219(8):. PubMed ID: 32697819
[TBL] [Abstract][Full Text] [Related]
16. Acetylation as a major determinant to microtubule-dependent autophagy: Relevance to Alzheimer's and Parkinson disease pathology.
Esteves AR; Palma AM; Gomes R; Santos D; Silva DF; Cardoso SM
Biochim Biophys Acta Mol Basis Dis; 2019 Aug; 1865(8):2008-2023. PubMed ID: 30572013
[TBL] [Abstract][Full Text] [Related]
17. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
Mo Z; Zhao X; Liu H; Hu Q; Chen XQ; Pham J; Wei N; Liu Z; Zhou J; Burgess RW; Pfaff SL; Caskey CT; Wu C; Bai G; Yang XL
Nat Commun; 2018 Mar; 9(1):1007. PubMed ID: 29520015
[TBL] [Abstract][Full Text] [Related]
18. HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
Benoy V; Van Helleputte L; Prior R; d'Ydewalle C; Haeck W; Geens N; Scheveneels W; Schevenels B; Cader MZ; Talbot K; Kozikowski AP; Vanden Berghe P; Van Damme P; Robberecht W; Van Den Bosch L
Brain; 2018 Mar; 141(3):673-687. PubMed ID: 29415205
[TBL] [Abstract][Full Text] [Related]
19. HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness.
Leyk J; Daly C; Janssen-Bienhold U; Kennedy BN; Richter-Landsberg C
Cell Death Dis; 2017 Aug; 8(8):e3028. PubMed ID: 29048427
[TBL] [Abstract][Full Text] [Related]
20. HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes.
Noack M; Leyk J; Richter-Landsberg C
Glia; 2014 Apr; 62(4):535-47. PubMed ID: 24464872
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
