These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 34340303)

  • 1. Why All the Fury over Furin?
    Osman EEA; Rehemtulla A; Neamati N
    J Med Chem; 2022 Feb; 65(4):2747-2784. PubMed ID: 34340303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting furin, a cellular proprotein convertase, for COVID-19 prevention and therapeutics.
    Jiang X; Li D; Maghsoudloo M; Zhang X; Ma W; Fu J
    Drug Discov Today; 2024 Jul; 29(7):104026. PubMed ID: 38762086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Screening of Small-Molecule Libraries Using SARS-CoV-2-Derived Sequences Identifies Novel Furin Inhibitors.
    Jorkesh A; Rothenberger S; Baldassar L; Grybaite B; Kavaliauskas P; Mickevicius V; Dettin M; Vascon F; Cendron L; Pasquato A
    Int J Mol Sci; 2024 May; 25(10):. PubMed ID: 38791119
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein.
    Sun C; Zhang J; Wei J; Zheng X; Zhao X; Fang Z; Xu D; Yuan H; Liu Y
    PLoS One; 2021; 16(1):e0245975. PubMed ID: 33493227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SARS-CoV-2 Spike Furin Cleavage Site and S2' Basic Residues Modulate the Entry Process in a Host Cell-Dependent Manner.
    Lavie M; Dubuisson J; Belouzard S
    J Virol; 2022 Jul; 96(13):e0047422. PubMed ID: 35678602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: Effects on proteolytic cleavage and ACE2 binding.
    Spelios MG; Capanelli JM; Li AW
    Immunol Lett; 2022 Feb; 242():1-7. PubMed ID: 35007661
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin.
    Tang T; Jaimes JA; Bidon MK; Straus MR; Daniel S; Whittaker GR
    ACS Infect Dis; 2021 Feb; 7(2):264-272. PubMed ID: 33432808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity.
    Essalmani R; Jain J; Susan-Resiga D; Andréo U; Evagelidis A; Derbali RM; Huynh DN; Dallaire F; Laporte M; Delpal A; Sutto-Ortiz P; Coutard B; Mapa C; Wilcoxen K; Decroly E; Nq Pham T; Cohen ÉA; Seidah NG
    J Virol; 2022 Apr; 96(8):e0012822. PubMed ID: 35343766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19.
    Kumar Tiwari P; Chouhan M; Mishra R; Gupta S; Chaudhary AA; Al-Zharani M; Ahmed Qurtam A; Nasr FA; Jha NK; Pant K; Kumar M; Kumar S
    Front Cell Infect Microbiol; 2024; 14():1391288. PubMed ID: 38919703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.
    Hoffmann M; Kleine-Weber H; Pöhlmann S
    Mol Cell; 2020 May; 78(4):779-784.e5. PubMed ID: 32362314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Research Progress on Spike-Dependent SARS-CoV-2 Fusion Inhibitors and Small Molecules Targeting the S2 Subunit of Spike.
    Freidel MR; Armen RS
    Viruses; 2024 Apr; 16(5):. PubMed ID: 38793593
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning from Past Discoveries to Advance COVID-19 Drug Discovery.
    Sabbah DA; Hajjo R; Bardaweel SK; Zhong HA
    Curr Top Med Chem; 2021; 21(7):571-596. PubMed ID: 33463470
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity.
    Wang S; Ran W; Sun L; Fan Q; Zhao Y; Wang B; Yang J; He Y; Wu Y; Wang Y; Chen L; Chuchuay A; You Y; Zhu X; Wang X; Chen Y; Wang Y; Chen YQ; Yuan Y; Zhao J; Mao Y
    Nat Commun; 2024 May; 15(1):4162. PubMed ID: 38755139
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects.
    Cheng YW; Chao TL; Li CL; Chiu MF; Kao HC; Wang SH; Pang YH; Lin CH; Tsai YM; Lee WH; Tao MH; Ho TC; Wu PY; Jang LT; Chen PJ; Chang SY; Yeh SH
    Cell Rep; 2020 Oct; 33(2):108254. PubMed ID: 33007239
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV.
    Örd M; Faustova I; Loog M
    Sci Rep; 2020 Oct; 10(1):16944. PubMed ID: 33037310
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets.
    Peacock TP; Goldhill DH; Zhou J; Baillon L; Frise R; Swann OC; Kugathasan R; Penn R; Brown JC; Sanchez-David RY; Braga L; Williamson MK; Hassard JA; Staller E; Hanley B; Osborn M; Giacca M; Davidson AD; Matthews DA; Barclay WS
    Nat Microbiol; 2021 Jul; 6(7):899-909. PubMed ID: 33907312
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2.
    Winstone H; Lista MJ; Reid AC; Bouton C; Pickering S; Galao RP; Kerridge C; Doores KJ; Swanson CM; Neil SJD
    J Virol; 2021 Apr; 95(9):. PubMed ID: 33563656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication.
    Singh S; O'Reilly S; Gewaid H; Bowie AG; Gautier V; Worrall DM
    Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293378
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms.
    Paiardi G; Richter S; Oreste P; Urbinati C; Rusnati M; Wade RC
    J Biol Chem; 2022 Feb; 298(2):101507. PubMed ID: 34929169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor.
    Wang J; Luo J; Wen Z; Wang X; Shuai L; Zhong G; Wang C; Sun Z; Chen W; Ge J; Liu R; Wang X; Bu Z
    mBio; 2022 Feb; 13(1):e0244321. PubMed ID: 35012335
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.