328 related articles for article (PubMed ID: 34343497)
1. Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.
Maurano M; Snyder JM; Connelly C; Henao-Mejia J; Sidrauski C; Stetson DB
Immunity; 2021 Sep; 54(9):1948-1960.e5. PubMed ID: 34343497
[TBL] [Abstract][Full Text] [Related]
2. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
Chung H; Calis JJA; Wu X; Sun T; Yu Y; Sarbanes SL; Dao Thi VL; Shilvock AR; Hoffmann HH; Rosenberg BR; Rice CM
Cell; 2018 Feb; 172(4):811-824.e14. PubMed ID: 29395325
[TBL] [Abstract][Full Text] [Related]
3. Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy.
Nakahama T; Kato Y; Shibuya T; Inoue M; Kim JI; Vongpipatana T; Todo H; Xing Y; Kawahara Y
Immunity; 2021 Sep; 54(9):1976-1988.e7. PubMed ID: 34525338
[TBL] [Abstract][Full Text] [Related]
4. Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain.
Guo X; Wiley CA; Steinman RA; Sheng Y; Ji B; Wang J; Zhang L; Wang T; Zenatai M; Billiar TR; Wang Q
J Neuroinflammation; 2021 Jul; 18(1):169. PubMed ID: 34332594
[TBL] [Abstract][Full Text] [Related]
5. Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.
Pestal K; Funk CC; Snyder JM; Price ND; Treuting PM; Stetson DB
Immunity; 2015 Nov; 43(5):933-44. PubMed ID: 26588779
[TBL] [Abstract][Full Text] [Related]
6. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs.
Yang S; Deng P; Zhu Z; Zhu J; Wang G; Zhang L; Chen AF; Wang T; Sarkar SN; Billiar TR; Wang Q
J Immunol; 2014 Oct; 193(7):3436-45. PubMed ID: 25172485
[TBL] [Abstract][Full Text] [Related]
7. RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency.
Stok JE; Oosenbrug T; Ter Haar LR; Gravekamp D; Bromley CP; Zelenay S; Reis e Sousa C; van der Veen AG
EMBO J; 2022 Mar; 41(6):e109760. PubMed ID: 35156720
[TBL] [Abstract][Full Text] [Related]
8. Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures.
Fisher AJ; Beal PA
RNA Biol; 2017 Feb; 14(2):164-170. PubMed ID: 27937139
[TBL] [Abstract][Full Text] [Related]
9. ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
de Reuver R; Verdonck S; Dierick E; Nemegeer J; Hessmann E; Ahmad S; Jans M; Blancke G; Van Nieuwerburgh F; Botzki A; Vereecke L; van Loo G; Declercq W; Hur S; Vandenabeele P; Maelfait J
Nature; 2022 Jul; 607(7920):784-789. PubMed ID: 35859175
[TBL] [Abstract][Full Text] [Related]
10. Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1.
Karki A; Campbell KB; Mozumder S; Fisher AJ; Beal PA
Biochemistry; 2024 Feb; 63(3):282-293. PubMed ID: 38190734
[TBL] [Abstract][Full Text] [Related]
11. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways.
Nakahama T; Kawahara Y
Int Immunol; 2023 Mar; 35(3):123-133. PubMed ID: 36469491
[TBL] [Abstract][Full Text] [Related]
12. An Aicardi-Goutières Syndrome-Causative Point Mutation in
Inoue M; Nakahama T; Yamasaki R; Shibuya T; Kim JI; Todo H; Xing Y; Kato Y; Morii E; Kawahara Y
J Immunol; 2021 Dec; 207(12):3016-3027. PubMed ID: 34772697
[TBL] [Abstract][Full Text] [Related]
13. Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.
Tang Q; Rigby RE; Young GR; Hvidt AK; Davis T; Tan TK; Bridgeman A; Townsend AR; Kassiotis G; Rehwinkel J
Immunity; 2021 Sep; 54(9):1961-1975.e5. PubMed ID: 34525337
[TBL] [Abstract][Full Text] [Related]
14. The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Mannion NM; Greenwood SM; Young R; Cox S; Brindle J; Read D; Nellåker C; Vesely C; Ponting CP; McLaughlin PJ; Jantsch MF; Dorin J; Adams IR; Scadden AD; Ohman M; Keegan LP; O'Connell MA
Cell Rep; 2014 Nov; 9(4):1482-94. PubMed ID: 25456137
[TBL] [Abstract][Full Text] [Related]
15. Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Rice GI; Kasher PR; Forte GM; Mannion NM; Greenwood SM; Szynkiewicz M; Dickerson JE; Bhaskar SS; Zampini M; Briggs TA; Jenkinson EM; Bacino CA; Battini R; Bertini E; Brogan PA; Brueton LA; Carpanelli M; De Laet C; de Lonlay P; del Toro M; Desguerre I; Fazzi E; Garcia-Cazorla A; Heiberg A; Kawaguchi M; Kumar R; Lin JP; Lourenco CM; Male AM; Marques W; Mignot C; Olivieri I; Orcesi S; Prabhakar P; Rasmussen M; Robinson RA; Rozenberg F; Schmidt JL; Steindl K; Tan TY; van der Merwe WG; Vanderver A; Vassallo G; Wakeling EL; Wassmer E; Whittaker E; Livingston JH; Lebon P; Suzuki T; McLaughlin PJ; Keegan LP; O'Connell MA; Lovell SC; Crow YJ
Nat Genet; 2012 Nov; 44(11):1243-8. PubMed ID: 23001123
[TBL] [Abstract][Full Text] [Related]
16. An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain.
Guo X; Steinman RA; Sheng Y; Cao G; Wiley CA; Wang Q
J Neuroinflammation; 2022 Dec; 19(1):285. PubMed ID: 36457126
[TBL] [Abstract][Full Text] [Related]
17. Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.
Cuadrado E; Michailidou I; van Bodegraven EJ; Jansen MH; Sluijs JA; Geerts D; Couraud PO; De Filippis L; Vescovi AL; Kuijpers TW; Hol EM
J Immunol; 2015 Apr; 194(8):3623-33. PubMed ID: 25769924
[TBL] [Abstract][Full Text] [Related]
18. Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in ADAR1.
Garcia L; Gonzalez CD; Gagne A; McGuire JA; French D; Takanohashi A; Almad A; Vanderver A; Sase S
Stem Cell Res; 2024 Feb; 74():103299. PubMed ID: 38181636
[TBL] [Abstract][Full Text] [Related]
19. Adenosine-to-inosine RNA editing in the immune system: friend or foe?
Nakahama T; Kawahara Y
Cell Mol Life Sci; 2020 Aug; 77(15):2931-2948. PubMed ID: 31996954
[TBL] [Abstract][Full Text] [Related]
20. Restricting retrotransposons: ADAR1 is another guardian of the human genome.
Orecchini E; Frassinelli L; Michienzi A
RNA Biol; 2017 Nov; 14(11):1485-1491. PubMed ID: 28640667
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
