BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 34344390)

  • 1. Similarities and differences in the localization, trafficking, and function of P-glycoprotein in MDR1-EGFP-transduced rat versus human brain capillary endothelial cell lines.
    Gericke B; Borsdorf S; Wienböker I; Noack A; Noack S; Löscher W
    Fluids Barriers CNS; 2021 Aug; 18(1):36. PubMed ID: 34344390
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C.
    Noack A; Noack S; Hoffmann A; Maalouf K; Buettner M; Couraud PO; Romero IA; Weksler B; Alms D; Römermann K; Naim HY; Löscher W
    PLoS One; 2014; 9(2):e88154. PubMed ID: 24505408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Marked differences in the effect of antiepileptic and cytostatic drugs on the functionality of P-glycoprotein in human and rat brain capillary endothelial cell lines.
    Alms D; Fedrowitz M; Römermann K; Noack A; Löscher W
    Pharm Res; 2014 Jun; 31(6):1588-604. PubMed ID: 24477677
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human brain microvascular endothelial cells release different types of P-glycoprotein-containing extracellular vesicles upon exposure to doxorubicin.
    Osten F; Löscher W; Gericke B
    Toxicol Appl Pharmacol; 2023 Nov; 479():116712. PubMed ID: 37820772
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood-brain barrier models for drug transport studies.
    Gericke B; Römermann K; Noack A; Noack S; Kronenberg J; Blasig IE; Löscher W
    Fluids Barriers CNS; 2020 Aug; 17(1):53. PubMed ID: 32843059
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model.
    Huber O; Brunner A; Maier P; Kaufmann R; Couraud PO; Cremer C; Fricker G
    PLoS One; 2012; 7(9):e44776. PubMed ID: 22984556
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Is P-Glycoprotein Functionally Expressed in the Limiting Membrane of Endolysosomes? A Biochemical and Ultrastructural Study in the Rat Liver.
    Gericke B; Wienböker I; Brandes G; Löscher W
    Cells; 2022 May; 11(9):. PubMed ID: 35563868
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier.
    Colclough N; Alluri RV; Tucker JW; Gozalpour E; Li D; Du H; Li W; Harlfinger S; O'Neill DJ; Sproat GG; Chen K; Yan Y; McGinnity DF
    Drug Metab Dispos; 2024 Jan; 52(2):95-105. PubMed ID: 38071533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells.
    Durk MR; Chan GN; Campos CR; Peart JC; Chow EC; Lee E; Cannon RE; Bendayan R; Miller DS; Pang KS
    J Neurochem; 2012 Dec; 123(6):944-53. PubMed ID: 23035695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
    Yu XY; Lin SG; Chen X; Zhou ZW; Liang J; Duan W; Chowbay B; Wen JY; Chan E; Cao J; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):365-78. PubMed ID: 17504224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An MDR-EGFP gene fusion allows for direct cellular localization, function and stability assessment of P-glycoprotein.
    Pétriz J; Gottesman MM; Aran JM
    Curr Drug Deliv; 2004 Jan; 1(1):43-56. PubMed ID: 16305369
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intercellular transfer of P-glycoprotein in human blood-brain barrier endothelial cells is increased by histone deacetylase inhibitors.
    Noack A; Noack S; Buettner M; Naim HY; Löscher W
    Sci Rep; 2016 Jul; 6():29253. PubMed ID: 27375084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport.
    Kuteykin-Teplyakov K; Luna-Tortós C; Ambroziak K; Löscher W
    Br J Pharmacol; 2010 Jul; 160(6):1453-63. PubMed ID: 20590635
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.
    Poller B; Gutmann H; Krähenbühl S; Weksler B; Romero I; Couraud PO; Tuffin G; Drewe J; Huwyler J
    J Neurochem; 2008 Dec; 107(5):1358-68. PubMed ID: 19013850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells.
    Svane N; Pedersen ABV; Rodenberg A; Ozgür B; Saaby L; Bundgaard C; Kristensen M; Tfelt-Hansen P; Brodin B
    Fluids Barriers CNS; 2024 May; 21(1):39. PubMed ID: 38711118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport.
    Veszelka S; Tóth A; Walter FR; Tóth AE; Gróf I; Mészáros M; Bocsik A; Hellinger É; Vastag M; Rákhely G; Deli MA
    Front Mol Neurosci; 2018; 11():166. PubMed ID: 29872378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells.
    Toth AE; Nielsen SSE; Tomaka W; Abbott NJ; Nielsen MS
    Fluids Barriers CNS; 2019 May; 16(1):14. PubMed ID: 31142333
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats.
    Hoffmann K; Löscher W
    Epilepsia; 2007 Apr; 48(4):631-45. PubMed ID: 17437408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATP-binding cassette transporters in primary central nervous system lymphoma: decreased expression of MDR1 P-glycoprotein and breast cancer resistance protein in tumor capillary endothelial cells.
    Sakata S; Fujiwara M; Ohtsuka K; Kamma H; Nagane M; Sakamoto A; Fujioka Y
    Oncol Rep; 2011 Feb; 25(2):333-9. PubMed ID: 21165575
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected].
    Carl SM; Lindley DJ; Das D; Couraud PO; Weksler BB; Romero I; Mowery SA; Knipp GT
    Mol Pharm; 2010 Aug; 7(4):1057-68. PubMed ID: 20524699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.