BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 34345835)

  • 1. The modulation of transcriptional expression and inhibition of multidrug resistance associated protein 4 (MRP4) by analgesics and their primary metabolites.
    Scialis RJ; Ghanem CI; Manautou JE
    Curr Res Toxicol; 2020 Jun; 1():34-41. PubMed ID: 34345835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes.
    Aleksunes LM; Campion SN; Goedken MJ; Manautou JE
    Toxicol Sci; 2008 Aug; 104(2):261-73. PubMed ID: 18468992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates.
    Koenderink JB; van den Heuvel JJMW; Bilos A; Vredenburg G; Vermeulen NPE; Russel FGM
    Arch Toxicol; 2020 Sep; 94(9):3027-3032. PubMed ID: 32472168
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity.
    Donepudi AC; Goedken MJ; Schuetz JD; E Manautou J
    Toxicol Rep; 2019; 6():841-849. PubMed ID: 31485416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function.
    Campion SN; Johnson R; Aleksunes LM; Goedken MJ; van Rooijen N; Scheffer GL; Cherrington NJ; Manautou JE
    Am J Physiol Gastrointest Liver Physiol; 2008 Aug; 295(2):G294-304. PubMed ID: 18556419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.
    Aleksunes LM; Slitt AL; Maher JM; Augustine LM; Goedken MJ; Chan JY; Cherrington NJ; Klaassen CD; Manautou JE
    Toxicol Appl Pharmacol; 2008 Jan; 226(1):74-83. PubMed ID: 17935745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
    Shimizu D; Ishitsuka Y; Miyata K; Tomishima Y; Kondo Y; Irikura M; Iwawaki T; Oike Y; Irie T
    Pharmacol Res; 2014 Sep; 87():26-41. PubMed ID: 24951965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acetaminophen Metabolites on Presentation Following an Acute Acetaminophen Overdose (ATOM-7).
    Chiew AL; Isbister GK; Stathakis P; Isoardi KZ; Page C; Ress K; Chan BSH; Buckley NA
    Clin Pharmacol Ther; 2023 Jun; 113(6):1304-1314. PubMed ID: 36919638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
    Zhang X; Wang T; Yang Y; Li R; Chen Y; Li R; Jiang X; Wang L
    Biomed Pharmacother; 2020 Oct; 130():110547. PubMed ID: 32777703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity.
    Aleksunes LM; Augustine LM; Cherrington NJ; Manautou JE
    J Toxicol Environ Health A; 2007 Nov; 70(21):1870-2. PubMed ID: 17934960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-acetylcysteine amide, a promising antidote for acetaminophen toxicity.
    Khayyat A; Tobwala S; Hart M; Ercal N
    Toxicol Lett; 2016 Jan; 241():133-42. PubMed ID: 26602168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sex difference in susceptibility to acetaminophen hepatotoxicity is reversed by buthionine sulfoximine.
    Masubuchi Y; Nakayama J; Watanabe Y
    Toxicology; 2011 Sep; 287(1-3):54-60. PubMed ID: 21672600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice.
    Zamek-Gliszczynski MJ; Nezasa K; Tian X; Bridges AS; Lee K; Belinsky MG; Kruh GD; Brouwer KL
    J Pharmacol Exp Ther; 2006 Dec; 319(3):1485-91. PubMed ID: 16988054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
    Ning C; Gao X; Wang C; Kong Y; Liu Z; Sun H; Sun P; Huo X; Ma X; Meng Q; Liu K
    Regul Toxicol Pharmacol; 2018 Oct; 98():58-68. PubMed ID: 30030101
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
    Ghanem CI; Rudraiah S; Bataille AM; Vigo MB; Goedken MJ; Manautou JE
    Biochem Pharmacol; 2015 Apr; 94(3):203-11. PubMed ID: 25667042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose.
    Ghanem CI; Ruiz ML; Villanueva SS; Luquita M; Llesuy S; Catania VA; Bengochea LA; Mottino AD
    Biochem Pharmacol; 2009 May; 77(10):1621-8. PubMed ID: 19426699
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease.
    Lickteig AJ; Fisher CD; Augustine LM; Aleksunes LM; Besselsen DG; Slitt AL; Manautou JE; Cherrington NJ
    Drug Metab Dispos; 2007 Oct; 35(10):1970-8. PubMed ID: 17640958
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases.
    Barnes SN; Aleksunes LM; Augustine L; Scheffer GL; Goedken MJ; Jakowski AB; Pruimboom-Brees IM; Cherrington NJ; Manautou JE
    Drug Metab Dispos; 2007 Oct; 35(10):1963-9. PubMed ID: 17627974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.
    Uzi D; Barda L; Scaiewicz V; Mills M; Mueller T; Gonzalez-Rodriguez A; Valverde AM; Iwawaki T; Nahmias Y; Xavier R; Chung RT; Tirosh B; Shibolet O
    J Hepatol; 2013 Sep; 59(3):495-503. PubMed ID: 23665281
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of Nrf2-related cytoprotective genes expression by acetaminophen-induced acute hepatotoxicity in mice and the protective role of betaine.
    Khodayar MJ; Kalantari H; Khorsandi L; Rashno M; Zeidooni L
    Hum Exp Toxicol; 2020 Jul; 39(7):948-959. PubMed ID: 32081044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.