These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 34349242)

  • 1. Wild-type IDH2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer.
    Qiao S; Lu W; Glorieux C; Li J; Zeng P; Meng N; Zhang H; Wen S; Huang P
    Oncogene; 2021 Sep; 40(39):5880-5892. PubMed ID: 34349242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone.
    Ge C; Wang Y; Feng Y; Wang S; Zhang K; Xu X; Zhang Z; Zhao Y; Wang Y; Gao L; Dai F; Xie S; Wang C
    Cancer Lett; 2021 Oct; 519():30-45. PubMed ID: 34166768
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wild-type IDH2 is a therapeutic target for triple-negative breast cancer.
    Li JJ; Yu T; Zeng P; Tian J; Liu P; Qiao S; Wen S; Hu Y; Liu Q; Lu W; Zhang H; Huang P
    Nat Commun; 2024 Apr; 15(1):3445. PubMed ID: 38658533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reductive TCA cycle catalyzed by wild-type IDH2 promotes acute myeloid leukemia and is a metabolic vulnerability for potential targeted therapy.
    Zeng P; Lu W; Tian J; Qiao S; Li J; Glorieux C; Wen S; Zhang H; Li Y; Huang P
    J Hematol Oncol; 2022 Mar; 15(1):30. PubMed ID: 35313945
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.
    Chen L; Fu L; Kong X; Xu J; Wang Z; Ma X; Akiyama Y; Chen Y; Fang J
    Br J Cancer; 2014 Feb; 110(4):1014-26. PubMed ID: 24473398
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
    He X; Wu N; Li R; Zhang H; Zhao Y; Nie Y; Wu J
    Cell Oncol (Dordr); 2023 Feb; 46(1):145-164. PubMed ID: 36401762
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IDH2 reprograms mitochondrial dynamics in cancer through a HIF-1α
    Wang Y; Agarwal E; Bertolini I; Ghosh JC; Seo JH; Altieri DC
    FASEB J; 2019 Dec; 33(12):13398-13411. PubMed ID: 31530011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
    Zhao P; Chen L; Li LH; Wei ZF; Tong B; Jia YG; Kong LY; Xia YF; Dai Y
    BMC Cancer; 2014 Dec; 14():987. PubMed ID: 25527123
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.
    Park JH; Ku HJ; Lee JH; Park JW
    Redox Biol; 2018 Jul; 17():16-24. PubMed ID: 29660504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.
    Deorukhkar A; Ahuja N; Mercado AL; Diagaradjane P; Raju U; Patel N; Mohindra P; Diep N; Guha S; Krishnan S
    Cancer Med; 2015 Feb; 4(2):278-92. PubMed ID: 25450478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wild-type IDH2 contributes to Epstein-Barr virus-dependent metabolic alterations and tumorigenesis.
    Shi F; He Y; Li J; Tang M; Li Y; Xie L; Zhao L; Hu J; Luo X; Zhou M; Liu N; Fan J; Zhou J; Gao Q; Qiu S; Wu W; Zhang X; Jia W; Bode AM; Cao Y
    Mol Metab; 2020 Jun; 36():100966. PubMed ID: 32224436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (
    Combès E; Andrade AF; Tosi D; Michaud HA; Coquel F; Garambois V; Desigaud D; Jarlier M; Coquelle A; Pasero P; Bonnefoy N; Moreaux J; Martineau P; Del Rio M; Beijersbergen RL; Vezzio-Vie N; Gongora C
    Cancer Res; 2019 Jun; 79(11):2933-2946. PubMed ID: 30987998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer.
    Bakkenist CJ; Lee JJ; Schmitz JC
    Clin Colorectal Cancer; 2018 Dec; 17(4):255-257. PubMed ID: 30316683
    [No Abstract]   [Full Text] [Related]  

  • 14. Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation.
    Kong L; Wang X; Zhang K; Yuan W; Yang Q; Fan J; Wang P; Liu Q
    PLoS One; 2015; 10(9):e0137888. PubMed ID: 26368019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/γH2AX pathway.
    Wang Z; Chen Q; Li B; Xie JM; Yang XD; Zhao K; Wu Y; Ye ZY; Chen ZR; Qin ZH; Xing CG
    Acta Pharmacol Sin; 2018 Oct; 39(10):1645-1660. PubMed ID: 29849127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants.
    Gao M; Zhu H; Fu L; Li Y; Bao X; Fu H; Quan H; Wang L; Lou L
    Cancer Sci; 2019 Oct; 110(10):3306-3314. PubMed ID: 31361380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Suppression of tumorigenesis in mitochondrial NADP(+)-dependent isocitrate dehydrogenase knock-out mice.
    Kim S; Kim SY; Ku HJ; Jeon YH; Lee HW; Lee J; Kwon TK; Park KM; Park JW
    Biochim Biophys Acta; 2014 Feb; 1842(2):135-43. PubMed ID: 24240089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. WBSCR22 confers oxaliplatin resistance in human colorectal cancer.
    Yan D; Tu L; Yuan H; Fang J; Cheng L; Zheng X; Wang X
    Sci Rep; 2017 Nov; 7(1):15443. PubMed ID: 29133897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heterogeneous nuclear ribonucleoprotein L facilitates recruitment of 53BP1 and BRCA1 at the DNA break sites induced by oxaliplatin in colorectal cancer.
    Hu W; Lei L; Xie X; Huang L; Cui Q; Dang T; Liu GL; Li Y; Sun X; Zhou Z
    Cell Death Dis; 2019 Jul; 10(8):550. PubMed ID: 31320608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Idh2 deficiency accelerates renal dysfunction in aged mice.
    Lee SJ; Cha H; Lee S; Kim H; Ku HJ; Kim SH; Park JH; Lee JH; Park KM; Park JW
    Biochem Biophys Res Commun; 2017 Nov; 493(1):34-39. PubMed ID: 28928092
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.