120 related articles for article (PubMed ID: 34350600)
1. Chrysin modulates protein kinase IKKε/TBK1, insulin sensitivity and hepatic fatty infiltration in diet-induced obese mice.
Amir Siddiqui M; Badruddeen ; Akhtar J; Uddin S; Chandrashekharan SM; Ahmad M; Khan MI; Khalid M
Drug Dev Res; 2022 Feb; 83(1):194-207. PubMed ID: 34350600
[TBL] [Abstract][Full Text] [Related]
2. IKKε is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity.
Weissmann L; Quaresma PG; Santos AC; de Matos AH; Pascoal VD; Zanotto TM; Castro G; Guadagnini D; da Silva JM; Velloso LA; Bittencourt JC; Lopes-Cendes I; Saad MJ; Prada PO
Diabetes; 2014 Oct; 63(10):3334-45. PubMed ID: 24812431
[TBL] [Abstract][Full Text] [Related]
3. Hepatic IKKε expression is dispensable for high-fat feeding-induced increases in liver lipid content and alterations in glucose tolerance.
Collier JJ; Batdorf HM; Mendoza TM; Burk DH; Martin TM; Zhang J; Mynatt RL; Burke SJ
Am J Physiol Endocrinol Metab; 2020 Jan; 318(1):E11-E21. PubMed ID: 31661298
[TBL] [Abstract][Full Text] [Related]
4. Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Cruz VH; Arner EN; Wynne KW; Scherer PE; Brekken RA
Mol Metab; 2018 Oct; 16():139-149. PubMed ID: 29935921
[TBL] [Abstract][Full Text] [Related]
5. The protein kinase IKKepsilon regulates energy balance in obese mice.
Chiang SH; Bazuine M; Lumeng CN; Geletka LM; Mowers J; White NM; Ma JT; Zhou J; Qi N; Westcott D; Delproposto JB; Blackwell TS; Yull FE; Saltiel AR
Cell; 2009 Sep; 138(5):961-75. PubMed ID: 19737522
[TBL] [Abstract][Full Text] [Related]
6. Amlexanox reversed non-alcoholic fatty liver disease through IKKε inhibition of hepatic stellate cell.
He Q; Xia X; Yao K; Zeng J; Wang W; Wu Q; Tang R; Zou X
Life Sci; 2019 Dec; 239():117010. PubMed ID: 31672578
[TBL] [Abstract][Full Text] [Related]
7. Resistance exercise attenuates IKKε phosphorylation and hepatic fat accumulation of obese mice.
Antunes GC; de Lima RD; Vieira RFL; Macêdo APA; Muñoz VR; Zambalde EP; Romeiro CF; Simabuco FM; Prada PO; da Silva ASR; Ropelle ER; Cintra DE; Pauli JR
Clin Exp Pharmacol Physiol; 2022 Oct; 49(10):1072-1081. PubMed ID: 35690890
[TBL] [Abstract][Full Text] [Related]
8. Long-term subcutaneous injection of lipopolysaccharides and high-fat diet induced non-alcoholic fatty liver disease through IKKε/ NF-κB signaling.
He Q; Zeng J; Yao K; Wang W; Wu Q; Tang R; Xia X; Zou X
Biochem Biophys Res Commun; 2020 Nov; 532(3):362-369. PubMed ID: 32883523
[TBL] [Abstract][Full Text] [Related]
9. Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro.
Zhou Z; Qi J; Lim CW; Kim JW; Kim B
Toxicology; 2020 Nov; 444():152579. PubMed ID: 32905826
[TBL] [Abstract][Full Text] [Related]
10. Medium-chain triglyceride ameliorates insulin resistance and inflammation in high fat diet-induced obese mice.
Geng S; Zhu W; Xie C; Li X; Wu J; Liang Z; Xie W; Zhu J; Huang C; Zhu M; Wu R; Zhong C
Eur J Nutr; 2016 Apr; 55(3):931-40. PubMed ID: 25911003
[TBL] [Abstract][Full Text] [Related]
11. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.
Clark K; Plater L; Peggie M; Cohen P
J Biol Chem; 2009 May; 284(21):14136-46. PubMed ID: 19307177
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity.
Beyett TS; Gan X; Reilly SM; Gomez AV; Chang L; Tesmer JJG; Saltiel AR; Showalter HD
Bioorg Med Chem; 2018 Nov; 26(20):5443-5461. PubMed ID: 30270002
[TBL] [Abstract][Full Text] [Related]
13. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.
Reilly SM; Chiang SH; Decker SJ; Chang L; Uhm M; Larsen MJ; Rubin JR; Mowers J; White NM; Hochberg I; Downes M; Yu RT; Liddle C; Evans RM; Oh D; Li P; Olefsky JM; Saltiel AR
Nat Med; 2013 Mar; 19(3):313-21. PubMed ID: 23396211
[TBL] [Abstract][Full Text] [Related]
14. Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis.
Hammaker D; Boyle DL; Firestein GS
Rheumatology (Oxford); 2012 Apr; 51(4):610-8. PubMed ID: 21613249
[TBL] [Abstract][Full Text] [Related]
15. Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes.
Zhang H; Chen L; Cai SH; Cheng H
Leuk Res; 2016 Jul; 46():37-44. PubMed ID: 27123832
[TBL] [Abstract][Full Text] [Related]
16. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition.
Reilly SM; Abu-Odeh M; Ameka M; DeLuca JH; Naber MC; Dadpey B; Ebadat N; Gomez AV; Peng X; Poirier B; Walk E; Potthoff MJ; Saltiel AR
J Clin Invest; 2021 May; 131(10):. PubMed ID: 33822771
[TBL] [Abstract][Full Text] [Related]
17. The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways.
Möller M; Wasel J; Schmetzer J; Weiß U; Meissner M; Schiffmann S; Weigert A; Möser CV; Niederberger E
Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32630674
[TBL] [Abstract][Full Text] [Related]
18. Role of chrysin on expression of insulin signaling molecules.
Satyanarayana K; Sravanthi K; Shaker IA; Ponnulakshmi R; Selvaraj J
J Ayurveda Integr Med; 2015; 6(4):248-58. PubMed ID: 26834424
[TBL] [Abstract][Full Text] [Related]
19. IKKε and TBK1 prevent RIPK1 dependent and independent inflammation.
Eren RO; Kaya GG; Schwarzer R; Pasparakis M
Nat Commun; 2024 Jan; 15(1):130. PubMed ID: 38167258
[TBL] [Abstract][Full Text] [Related]
20. The non-canonical IκB kinases IKKε and TBK1 as potential targets for the development of novel therapeutic drugs.
Niederberger E; Möser CV; Kynast KL; Geisslinger G
Curr Mol Med; 2013 Aug; 13(7):1089-97. PubMed ID: 23157677
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
