341 related articles for article (PubMed ID: 34354057)
1. Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design.
Lu S; He X; Yang Z; Chai Z; Zhou S; Wang J; Rehman AU; Ni D; Pu J; Sun J; Zhang J
Nat Commun; 2021 Aug; 12(1):4721. PubMed ID: 34354057
[TBL] [Abstract][Full Text] [Related]
2. Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.
Cabana J; Holleran B; Leduc R; Escher E; Guillemette G; Lavigne P
J Biol Chem; 2015 Jun; 290(25):15835-15854. PubMed ID: 25934394
[TBL] [Abstract][Full Text] [Related]
3. Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors.
Sleno R; Devost D; Pétrin D; Zhang A; Bourque K; Shinjo Y; Aoki J; Inoue A; Hébert TE
J Biol Chem; 2017 Jul; 292(29):12139-12152. PubMed ID: 28584054
[TBL] [Abstract][Full Text] [Related]
4. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
Wilson PC; Lee MH; Appleton KM; El-Shewy HM; Morinelli TA; Peterson YK; Luttrell LM; Jaffa AA
J Biol Chem; 2013 Jun; 288(26):18872-84. PubMed ID: 23661707
[TBL] [Abstract][Full Text] [Related]
5. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.
Namkung Y; LeGouill C; Kumar S; Cao Y; Teixeira LB; Lukasheva V; Giubilaro J; Simões SC; Longpré JM; Devost D; Hébert TE; Piñeyro G; Leduc R; Costa-Neto CM; Bouvier M; Laporte SA
Sci Signal; 2018 Dec; 11(559):. PubMed ID: 30514808
[TBL] [Abstract][Full Text] [Related]
6. Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.
Fu Y; Huang Y; Yang Z; Chen Y; Zheng J; Mao C; Li Z; Liu Z; Yu B; Li T; Wang M; Xu C; Zhou Y; Zhao G; Jia Y; Guo W; Jia X; Zhang T; Li L; Liu Z; Guo S; Ma M; Zhang H; Liu B; Du J; Wang W; Tang C; Gao P; Xu Q; Wang X; Liu J; Sun J; Kong W
Cell Res; 2021 Jul; 31(7):773-790. PubMed ID: 33510386
[TBL] [Abstract][Full Text] [Related]
7. Manifold active-state conformations in GPCRs: agonist-activated constitutively active mutant AT1 receptor preferentially couples to Gq compared to the wild-type AT1 receptor.
Lee C; Hwang SA; Jang SH; Chung HS; Bhat MB; Karnik SS
FEBS Lett; 2007 May; 581(13):2517-22. PubMed ID: 17498700
[TBL] [Abstract][Full Text] [Related]
8. Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.
Wingler LM; McMahon C; Staus DP; Lefkowitz RJ; Kruse AC
Cell; 2019 Jan; 176(3):479-490.e12. PubMed ID: 30639100
[TBL] [Abstract][Full Text] [Related]
9. Allosteric coupling and biased agonism in G protein-coupled receptors.
Bock A; Bermudez M
FEBS J; 2021 Apr; 288(8):2513-2528. PubMed ID: 33621418
[TBL] [Abstract][Full Text] [Related]
10. Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.
Tang W; Strachan RT; Lefkowitz RJ; Rockman HA
J Biol Chem; 2014 Oct; 289(41):28271-83. PubMed ID: 25170081
[TBL] [Abstract][Full Text] [Related]
11. Unraveling allostery within the angiotensin II type 1 receptor for Gα
Cao Y; van der Velden WJC; Namkung Y; Nivedha AK; Cho A; Sedki D; Holleran B; Lee N; Leduc R; Muk S; Le K; Bhattacharya S; Vaidehi N; Laporte SA
Sci Signal; 2023 Aug; 16(797):eadf2173. PubMed ID: 37552769
[TBL] [Abstract][Full Text] [Related]
12. Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes.
Delaitre C; Boisbrun M; Lecat S; Dupuis F
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34201646
[TBL] [Abstract][Full Text] [Related]
13. Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor.
Suomivuori CM; Latorraca NR; Wingler LM; Eismann S; King MC; Kleinhenz ALW; Skiba MA; Staus DP; Kruse AC; Lefkowitz RJ; Dror RO
Science; 2020 Feb; 367(6480):881-887. PubMed ID: 32079767
[TBL] [Abstract][Full Text] [Related]
14. Angiotensin II type 1 receptor variants alter endosomal receptor-β-arrestin complex stability and MAPK activation.
Cao Y; Kumar S; Namkung Y; Gagnon L; Cho A; Laporte SA
J Biol Chem; 2020 Sep; 295(38):13169-13180. PubMed ID: 32703898
[TBL] [Abstract][Full Text] [Related]
15. Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context.
Devost D; Sleno R; Pétrin D; Zhang A; Shinjo Y; Okde R; Aoki J; Inoue A; Hébert TE
J Biol Chem; 2017 Mar; 292(13):5443-5456. PubMed ID: 28213525
[TBL] [Abstract][Full Text] [Related]
16. Common activation mechanism of class A GPCRs.
Zhou Q; Yang D; Wu M; Guo Y; Guo W; Zhong L; Cai X; Dai A; Jang W; Shakhnovich EI; Liu ZJ; Stevens RC; Lambert NA; Babu MM; Wang MW; Zhao S
Elife; 2019 Dec; 8():. PubMed ID: 31855179
[TBL] [Abstract][Full Text] [Related]
17. Biased agonists differentially modulate the receptor conformation ensembles in Angiotensin II type 1 receptor.
Nivedha AK; Lee S; Vaidehi N
J Mol Graph Model; 2023 Jan; 118():108365. PubMed ID: 36335829
[TBL] [Abstract][Full Text] [Related]
18. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis.
Kendall RT; Lee MH; Pleasant DL; Robinson K; Kuppuswamy D; McDermott PJ; Luttrell LM
J Biol Chem; 2014 Sep; 289(38):26155-26166. PubMed ID: 25081544
[TBL] [Abstract][Full Text] [Related]
19. Allosteric communication regulates ligand-specific GPCR activity.
Ma N; Nivedha AK; Vaidehi N
FEBS J; 2021 Apr; 288(8):2502-2512. PubMed ID: 33738925
[TBL] [Abstract][Full Text] [Related]
20. Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction.
Reis RI; Santos EL; Pesquero JB; Oliveira L; Schanstra JP; Bascands JL; Pecher C; Paiva AC; Costa-Neto CM
Regul Pept; 2007 Apr; 140(1-2):32-6. PubMed ID: 17239455
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
