BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 34356050)

  • 1. Understanding BRCA2 Function as a Tumor Suppressor Based on Domain-Specific Activities in DNA Damage Responses.
    Andreassen PR; Seo J; Wiek C; Hanenberg H
    Genes (Basel); 2021 Jul; 12(7):. PubMed ID: 34356050
    [No Abstract]   [Full Text] [Related]  

  • 2. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.
    Siaud N; Barbera MA; Egashira A; Lam I; Christ N; Schlacher K; Xia B; Jasin M
    PLoS Genet; 2011 Dec; 7(12):e1002409. PubMed ID: 22194698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BRCA1 and BRCA2: different roles in a common pathway of genome protection.
    Roy R; Chun J; Powell SN
    Nat Rev Cancer; 2011 Dec; 12(1):68-78. PubMed ID: 22193408
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BRCA2 functions: from DNA repair to replication fork stabilization.
    Fradet-Turcotte A; Sitz J; Grapton D; Orthwein A
    Endocr Relat Cancer; 2016 Oct; 23(10):T1-T17. PubMed ID: 27530658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PALB2: the hub of a network of tumor suppressors involved in DNA damage responses.
    Park JY; Zhang F; Andreassen PR
    Biochim Biophys Acta; 2014 Aug; 1846(1):263-75. PubMed ID: 24998779
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
    Xia B; Sheng Q; Nakanishi K; Ohashi A; Wu J; Christ N; Liu X; Jasin M; Couch FJ; Livingston DM
    Mol Cell; 2006 Jun; 22(6):719-729. PubMed ID: 16793542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic exploitation of tumor cell defects in homologous recombination.
    Powell SN; Kachnic LA
    Anticancer Agents Med Chem; 2008 May; 8(4):448-60. PubMed ID: 18473729
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Guardians of the Genome: BRCA2 and Its Partners.
    Le HP; Heyer WD; Liu J
    Genes (Basel); 2021 Aug; 12(8):. PubMed ID: 34440403
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.
    Biswas K; Das R; Eggington JM; Qiao H; North SL; Stauffer S; Burkett SS; Martin BK; Southon E; Sizemore SC; Pruss D; Bowles KR; Roa BB; Hunter N; Tessarollo L; Wenstrup RJ; Byrd RA; Sharan SK
    Hum Mol Genet; 2012 Sep; 21(18):3993-4006. PubMed ID: 22678057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25773776
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PALB2 links BRCA1 and BRCA2 in the DNA-damage response.
    Zhang F; Ma J; Wu J; Ye L; Cai H; Xia B; Yu X
    Curr Biol; 2009 Mar; 19(6):524-9. PubMed ID: 19268590
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance.
    Menzel T; Nähse-Kumpf V; Kousholt AN; Klein DK; Lund-Andersen C; Lees M; Johansen JV; Syljuåsen RG; Sørensen CS
    EMBO Rep; 2011 Jul; 12(7):705-12. PubMed ID: 21637299
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of the expression of BRCA2 on spontaneous homologous recombination and DNA damage-induced nuclear foci in Saccharomyces cerevisiae.
    Spugnesi L; Balia C; Collavoli A; Falaschi E; Quercioli V; Caligo MA; Galli A
    Mutagenesis; 2013 Mar; 28(2):187-95. PubMed ID: 23328489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.
    Zhao W; Wiese C; Kwon Y; Hromas R; Sung P
    Annu Rev Biochem; 2019 Jun; 88():221-245. PubMed ID: 30917004
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
    Ohashi A; Zdzienicka MZ; Chen J; Couch FJ
    J Biol Chem; 2005 Apr; 280(15):14877-83. PubMed ID: 15671039
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
    Park JY; Singh TR; Nassar N; Zhang F; Freund M; Hanenberg H; Meetei AR; Andreassen PR
    Oncogene; 2014 Oct; 33(40):4803-12. PubMed ID: 24141787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks.
    Buisson R; Niraj J; Pauty J; Maity R; Zhao W; Coulombe Y; Sung P; Masson JY
    Cell Rep; 2014 Feb; 6(3):553-64. PubMed ID: 24485656
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heterozygous mutations in PALB2 cause DNA replication and damage response defects.
    Nikkilä J; Parplys AC; Pylkäs K; Bose M; Huo Y; Borgmann K; Rapakko K; Nieminen P; Xia B; Pospiech H; Winqvist R
    Nat Commun; 2013; 4():2578. PubMed ID: 24153426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.