These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 34358645)

  • 1. Ceramide synthase 6 mediates sex-specific metabolic response to dietary folic acid in mice.
    Barron K; Ogretmen B; Krupenko N
    J Nutr Biochem; 2021 Dec; 98():108832. PubMed ID: 34358645
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.
    Raichur S; Brunner B; Bielohuby M; Hansen G; Pfenninger A; Wang B; Bruning JC; Larsen PJ; Tennagels N
    Mol Metab; 2019 Mar; 21():36-50. PubMed ID: 30655217
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.
    Senkal CE; Ponnusamy S; Manevich Y; Meyers-Needham M; Saddoughi SA; Mukhopadyay A; Dent P; Bielawski J; Ogretmen B
    J Biol Chem; 2011 Dec; 286(49):42446-42458. PubMed ID: 22013072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
    Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
    J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation.
    Jeon S; Scorletti E; Dempsey J; Buyco D; Lin C; Saiman Y; Bayen S; Harkin J; Martin J; Hooks R; Ogretmen B; Argemi J; Melo L; Bataller R; Carr RM
    Mol Metab; 2023 Dec; 78():101804. PubMed ID: 37714377
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Widespread tissue distribution and synthetic pathway of polyunsaturated C24:2 sphingolipids in mammals.
    Edagawa M; Sawai M; Ohno Y; Kihara A
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Dec; 1863(12):1441-1448. PubMed ID: 30251650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury.
    Liu Y; Sun Z; Sun Q; Wang L; Wang C; Li Y; Ma C; Shi W; Zhang G; Dong Y; Zhang X; Cong B
    Lipids Health Dis; 2024 Mar; 23(1):68. PubMed ID: 38431645
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance.
    Turpin SM; Nicholls HT; Willmes DM; Mourier A; Brodesser S; Wunderlich CM; Mauer J; Xu E; Hammerschmidt P; Brönneke HS; Trifunovic A; LoSasso G; Wunderlich FT; Kornfeld JW; Blüher M; Krönke M; Brüning JC
    Cell Metab; 2014 Oct; 20(4):678-86. PubMed ID: 25295788
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6.
    Hoeferlin LA; Fekry B; Ogretmen B; Krupenko SA; Krupenko NI
    J Biol Chem; 2013 May; 288(18):12880-90. PubMed ID: 23519469
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dietary Folic Acid Alters Metabolism of Multiple Vitamins in a CerS6- and Sex-Dependent Manner.
    Barron K; Ogretmen B; Krupenko N
    Front Nutr; 2021; 8():758403. PubMed ID: 34805245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide.
    Yamaji T; Horie A; Tachida Y; Sakuma C; Suzuki Y; Kushi Y; Hanada K
    Int J Mol Sci; 2016 Oct; 17(10):. PubMed ID: 27775668
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.
    Pewzner-Jung Y; Park H; Laviad EL; Silva LC; Lahiri S; Stiban J; Erez-Roman R; Brügger B; Sachsenheimer T; Wieland F; Prieto M; Merrill AH; Futerman AH
    J Biol Chem; 2010 Apr; 285(14):10902-10. PubMed ID: 20110363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
    Ebel P; Vom Dorp K; Petrasch-Parwez E; Zlomuzica A; Kinugawa K; Mariani J; Minich D; Ginkel C; Welcker J; Degen J; Eckhardt M; Dere E; Dörmann P; Willecke K
    J Biol Chem; 2013 Jul; 288(29):21433-21447. PubMed ID: 23760501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
    Senkal CE; Ponnusamy S; Bielawski J; Hannun YA; Ogretmen B
    FASEB J; 2010 Jan; 24(1):296-308. PubMed ID: 19723703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis.
    Scheffel MJ; Helke K; Lu P; Bowers JS; Ogretmen B; Garrett-Mayer E; Paulos CM; Voelkel-Johnson C
    Sci Rep; 2017 Nov; 7(1):15552. PubMed ID: 29138469
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer.
    Lee WK; Maaß M; Quach A; Poscic N; Prangley H; Pallott EC; Kim JL; Pierce JS; Ogretmen B; Futerman AH; Thévenod F
    J Biol Chem; 2022 Feb; 298(2):101492. PubMed ID: 34915026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent Manner.
    Fekry B; Esmaeilniakooshkghazi A; Krupenko SA; Krupenko NI
    PLoS One; 2016; 11(1):e0146618. PubMed ID: 26783755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Danhe granule ameliorates nonalcoholic steatohepatitis and fibrosis in rats by inhibiting ceramide de novo synthesis related to CerS6 and CerK.
    Zhu M; Jia Z; Yan X; Liu L; Fang C; Feng M; Dai Y; Zhang Y; Wu H; Huang B; Li Y; Liu J; Xiao H
    J Ethnopharmacol; 2022 Sep; 295():115427. PubMed ID: 35654350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
    Hammerschmidt P; Ostkotte D; Nolte H; Gerl MJ; Jais A; Brunner HL; Sprenger HG; Awazawa M; Nicholls HT; Turpin-Nolan SM; Langer T; Krüger M; Brügger B; Brüning JC
    Cell; 2019 May; 177(6):1536-1552.e23. PubMed ID: 31150623
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
    Verlekar D; Wei SJ; Cho H; Yang S; Kang MH
    Cell Death Dis; 2018 Sep; 9(9):925. PubMed ID: 30206207
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.