183 related articles for article (PubMed ID: 34359777)
1. WIP1 Inhibition by GSK2830371 Potentiates HDM201 through Enhanced p53 Phosphorylation and Activation in Liver Adenocarcinoma Cells.
Wu CE; Huang CY; Chen CP; Pan YR; Chang JW; Chen JS; Yeh CN; Lunec J
Cancers (Basel); 2021 Jul; 13(15):. PubMed ID: 34359777
[TBL] [Abstract][Full Text] [Related]
2.
Wu CE; Chen CP; Pan YR; Jung SM; Chang JW; Chen JS; Yeh CN; Lunec J
Am J Cancer Res; 2022; 12(9):4399-4410. PubMed ID: 36225643
[TBL] [Abstract][Full Text] [Related]
3. Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.
Wu CE; Esfandiari A; Ho YH; Wang N; Mahdi AK; Aptullahoglu E; Lovat P; Lunec J
Br J Cancer; 2018 Feb; 118(4):495-508. PubMed ID: 29235570
[TBL] [Abstract][Full Text] [Related]
4. Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner.
Esfandiari A; Hawthorne TA; Nakjang S; Lunec J
Mol Cancer Ther; 2016 Mar; 15(3):379-91. PubMed ID: 26832796
[TBL] [Abstract][Full Text] [Related]
5. Tipping Growth Inhibition into Apoptosis by Combining Treatment with MDM2 and WIP1 Inhibitors in p53
Chamberlain V; Drew Y; Lunec J
Cancers (Basel); 2021 Dec; 14(1):. PubMed ID: 35008180
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3.
Pechackova S; Burdova K; Benada J; Kleiblova P; Jenikova G; Macurek L
Oncotarget; 2016 Mar; 7(12):14458-75. PubMed ID: 26883108
[TBL] [Abstract][Full Text] [Related]
7. Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity.
Sriraman A; Radovanovic M; Wienken M; Najafova Z; Li Y; Dobbelstein M
Oncotarget; 2016 May; 7(22):31623-38. PubMed ID: 27183917
[TBL] [Abstract][Full Text] [Related]
8. Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis.
Chen Z; Wang L; Yao D; Yang T; Cao WM; Dou J; Pang JC; Guan S; Zhang H; Yu Y; Zhao Y; Wang Y; Xu X; Shi Y; Patel R; Zhang H; Vasudevan SA; Liu S; Yang J; Nuchtern JG
Sci Rep; 2016 Dec; 6():38011. PubMed ID: 27991505
[TBL] [Abstract][Full Text] [Related]
9. The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma.
Kojima K; Maeda A; Yoshimura M; Nishida Y; Kimura S
Oncotarget; 2016 Oct; 7(43):69625-69637. PubMed ID: 27626308
[TBL] [Abstract][Full Text] [Related]
10. Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.
Jeay S; Ferretti S; Holzer P; Fuchs J; Chapeau EA; Wartmann M; Sterker D; Romanet V; Murakami M; Kerr G; Durand EY; Gaulis S; Cortes-Cros M; Ruetz S; Stachyra TM; Kallen J; Furet P; Würthner J; Guerreiro N; Halilovic E; Jullion A; Kauffmann A; Kuriakose E; Wiesmann M; Jensen MR; Hofmann F; Sellers WR
Cancer Res; 2018 Nov; 78(21):6257-6267. PubMed ID: 30135191
[TBL] [Abstract][Full Text] [Related]
11. WIP1 phosphatase as a potential therapeutic target in neuroblastoma.
Richter M; Dayaram T; Gilmartin AG; Ganji G; Pemmasani SK; Van Der Key H; Shohet JM; Donehower LA; Kumar R
PLoS One; 2015; 10(2):e0115635. PubMed ID: 25658463
[TBL] [Abstract][Full Text] [Related]
12. ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma.
Wu CE; Koay TS; Esfandiari A; Ho YH; Lovat P; Lunec J
Cancers (Basel); 2018 Dec; 11(1):. PubMed ID: 30577494
[TBL] [Abstract][Full Text] [Related]
13. Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy.
Clausse V; Goloudina AR; Uyanik B; Kochetkova EY; Richaud S; Fedorova OA; Hammann A; Bardou M; Barlev NA; Garrido C; Demidov ON
Cell Death Dis; 2016 Apr; 7(4):e2195. PubMed ID: 27077811
[TBL] [Abstract][Full Text] [Related]
14. Wild-type p53-induced phosphatase 1 (WIP1) regulates the proliferation of swine Sertoli cells through P53.
Wang B; Zhang M; Che J; Li K; Mu Y; Liu Z
Reprod Fertil Dev; 2020 Dec; 32(18):1350-1356. PubMed ID: 33287951
[TBL] [Abstract][Full Text] [Related]
15. The Regulation of Trophoblastic p53 Homeostasis by the p38-Wip1 Feedback Loop is Disturbed in Placentas from Pregnancies Complicated by Preeclampsia.
Tan B; Tong C; Yuan Y; Xu P; Wen L; Zhang C; Zheng Y; Lin L; Zhu F; Gui S; Wang L; Gao R; Li J; Qi H; Baker PN
Cell Physiol Biochem; 2019; 52(2):315-335. PubMed ID: 30816677
[TBL] [Abstract][Full Text] [Related]
16. Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a.
Fontana MC; Nanni J; Ghelli Luserna di Rorà A; Petracci E; Padella A; Ghetti M; Ferrari A; Marconi G; Soverini S; Iacobucci I; Papayannidis C; Curti A; Audisio E; Giannini MB; Rondoni M; Lanza F; Cavo M; Martinelli G; Simonetti G
Biomedicines; 2021 Apr; 9(4):. PubMed ID: 33917342
[TBL] [Abstract][Full Text] [Related]
17. MDM2- and FLT3-inhibitors in the treatment of
Seipel K; Marques MAT; Sidler C; Mueller BU; Pabst T
Haematologica; 2018 Nov; 103(11):1862-1872. PubMed ID: 29976747
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin.
Zhang L; Liu L; He Z; Li G; Liu J; Song Z; Jin H; Rudolph KL; Yang H; Mao Y; Zhang L; Zhang H; Xiao Z; Ju Z
Hepatology; 2015 Jun; 61(6):2030-41. PubMed ID: 25704606
[TBL] [Abstract][Full Text] [Related]
19. The Wip1 phosphatase and Mdm2: cracking the "Wip" on p53 stability.
Lu X; Nguyen TA; Zhang X; Donehower LA
Cell Cycle; 2008 Jan; 7(2):164-8. PubMed ID: 18333294
[TBL] [Abstract][Full Text] [Related]
20. P65-mediated miR-590 inhibition modulates the chemoresistance of osteosarcoma to doxorubicin through targeting wild-type p53-induced phosphatase 1.
Long X; Lin XJ
J Cell Biochem; 2019 Apr; 120(4):5652-5665. PubMed ID: 30387173
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
