BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 34366294)

  • 21. Activation of gp130 signaling in T cells drives T
    Baumgartner F; Bamopoulos SA; Faletti L; Hsiao HJ; Holz M; Gonzalez-Menendez I; Solé-Boldo L; Horne A; Gosavi S; Özerdem C; Singh N; Liebig S; Ramamoorthy S; Lehmann M; Demel U; Kühl AA; Wartewig T; Ruland J; Wunderlich FT; Schick M; Walther W; Rose-John S; Haas S; Quintanilla-Martinez L; Feske S; Ehl S; Glauben R; Keller U
    Sci Signal; 2024 Feb; 17(824):eadc9662. PubMed ID: 38377177
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Case Report: Signal Transducer and Activator of Transcription 3 Gain-of-Function and Spectrin Deficiency: A Life-Threatening Case of Severe Hemolytic Anemia.
    Ciullini Mannurita S; Goda R; Schiavo E; Coniglio ML; Azzali A; Fotzi I; Tondo A; Tintori V; Frenos S; Sanvito MC; Vignoli M; Luceri C; Bigagli E; Grassi A; D'Elios MM; Favre C; Gambineri E
    Front Immunol; 2020; 11():620046. PubMed ID: 33519826
    [No Abstract]   [Full Text] [Related]  

  • 23. Early-onset, fatal interstitial lung disease in STAT3 gain-of-function patients.
    Gothe F; Gehrig J; Rapp CK; Knoflach K; Reu-Hofer S; Länger F; Schramm D; Ley-Zaporozhan J; Ehl S; Schwerk N; Faletti L; Griese M
    Pediatr Pulmonol; 2021 Dec; 56(12):3934-3941. PubMed ID: 34549903
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human T
    Zhang Y; Siegel AM; Sun G; Dimaggio T; Freeman AF; Milner JD
    J Allergy Clin Immunol; 2019 Mar; 143(3):1108-1118.e4. PubMed ID: 30030006
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice.
    Toth KA; Schmitt EG; Kolicheski A; Greenberg ZJ; Levendosky E; Saucier N; Trammel K; Oikonomou V; Lionakis MS; Klechevsky E; Kim BS; Schuettpelz LG; Saligrama N; Cooper MA
    J Exp Med; 2024 Aug; 221(8):. PubMed ID: 38861030
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Clinical Relevance of Gain- and Loss-of-Function Germline Mutations in STAT1: A Systematic Review.
    Zhang W; Chen X; Gao G; Xing S; Zhou L; Tang X; Zhao X; An Y
    Front Immunol; 2021; 12():654406. PubMed ID: 33777053
    [No Abstract]   [Full Text] [Related]  

  • 27. STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D
    Masle-Farquhar E; Jackson KJL; Peters TJ; Al-Eryani G; Singh M; Payne KJ; Rao G; Avery DT; Apps G; Kingham J; Jara CJ; Skvortsova K; Swarbrick A; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O'Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC
    Immunity; 2022 Dec; 55(12):2386-2404.e8. PubMed ID: 36446385
    [TBL] [Abstract][Full Text] [Related]  

  • 28. STAT3-confusion-of-function: Beyond the loss and gain dualism.
    Lodi L; Faletti LE; Maccari ME; Consonni F; Groß M; Pagnini I; Ricci S; Heeg M; Simonini G; Azzari C; Ehl S
    J Allergy Clin Immunol; 2022 Nov; 150(5):1237-1241.e3. PubMed ID: 35750105
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A multifaceted disease: The stats of STAT3 GOF.
    Freeman AF; Bergerson JRE
    J Allergy Clin Immunol; 2023 Apr; 151(4):901-903. PubMed ID: 36813184
    [No Abstract]   [Full Text] [Related]  

  • 30. Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.
    Edwards ESJ; Bier J; Cole TS; Wong M; Hsu P; Berglund LJ; Boztug K; Lau A; Gostick E; Price DA; O'Sullivan M; Meyts I; Choo S; Gray P; Holland SM; Deenick EK; Uzel G; Tangye SG
    J Allergy Clin Immunol; 2019 Jan; 143(1):276-291.e6. PubMed ID: 29800648
    [TBL] [Abstract][Full Text] [Related]  

  • 31. STAT1 and STAT3 mutations: important lessons for clinical immunologists.
    Olbrich P; Freeman AF
    Expert Rev Clin Immunol; 2018 Dec; 14(12):1029-1041. PubMed ID: 30280610
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond.
    ;
    Trends Immunol; 2024 Feb; 45(2):138-153. PubMed ID: 38238227
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses.
    Deenick EK; Pelham SJ; Kane A; Ma CS
    Front Immunol; 2018; 9():168. PubMed ID: 29472924
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Short Stature in a Boy with Multiple Early-Onset Autoimmune Conditions due to a STAT3 Activating Mutation: Could Intracellular Growth Hormone Signalling Be Compromised?
.
    Sediva H; Dusatkova P; Kanderova V; Obermannova B; Kayserova J; Sramkova L; Zemkova D; Elblova L; Svaton M; Zachova R; Kolouskova S; Fronkova E; Sumnik Z; Sediva A; Lebl J; Pruhova S
    Horm Res Paediatr; 2017; 88(2):160-166. PubMed ID: 28253502
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Janus kinase inhibitors ameliorate clinical symptoms in patients with STAT3 gain-of-function.
    Kaneko S; Sakura F; Tanita K; Shimbo A; Nambu R; Yoshida M; Umetsu S; Inui A; Okada C; Tsumura M; Yamada M; Suzuki H; Kosaki K; Ohara O; Shimizu M; Morio T; Okada S; Kanegane H
    Immunother Adv; 2023; 3(1):ltad027. PubMed ID: 38549698
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Efficacy of tocilizumab therapy in a patient with severe pancytopenia associated with a STAT3 gain-of-function mutation.
    Wang W; Liu L; Hui X; Wang Y; Ying W; Zhou Q; Hou J; Yang M; Sun B; Sun J; Wang X
    BMC Immunol; 2021 Mar; 22(1):19. PubMed ID: 33731004
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease.
    Flanagan SE; Haapaniemi E; Russell MA; Caswell R; Allen HL; De Franco E; McDonald TJ; Rajala H; Ramelius A; Barton J; Heiskanen K; Heiskanen-Kosma T; Kajosaari M; Murphy NP; Milenkovic T; Seppänen M; Lernmark Å; Mustjoki S; Otonkoski T; Kere J; Morgan NG; Ellard S; Hattersley AT
    Nat Genet; 2014 Aug; 46(8):812-814. PubMed ID: 25038750
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dysregulatory syndromes: the role of signal transducers and activators of transcription.
    Bezrodnik L; Gaillard MI; Caldirola MS
    Curr Opin Pediatr; 2018 Dec; 30(6):821-828. PubMed ID: 30407975
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.
    Haapaniemi EM; Kaustio M; Rajala HL; van Adrichem AJ; Kainulainen L; Glumoff V; Doffinger R; Kuusanmäki H; Heiskanen-Kosma T; Trotta L; Chiang S; Kulmala P; Eldfors S; Katainen R; Siitonen S; Karjalainen-Lindsberg ML; Kovanen PE; Otonkoski T; Porkka K; Heiskanen K; Hänninen A; Bryceson YT; Uusitalo-Seppälä R; Saarela J; Seppänen M; Mustjoki S; Kere J
    Blood; 2015 Jan; 125(4):639-48. PubMed ID: 25349174
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction.
    Woods J; Pemberton SE; Largent AD; Chiang K; Liggitt D; Oukka M; Rawlings DJ; Jackson SW
    J Immunol; 2022 Sep; 209(6):1033-1038. PubMed ID: 35995509
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.