200 related articles for article (PubMed ID: 34370156)
1. The influence of an enamine usnic acid derivative (a tyrosyl-DNA phosphodiesterase 1 inhibitor) on the therapeutic effect of topotecan against transplanted tumors in vivo.
Nikolin VP; Popova NA; Kaledin VI; Luzina OA; Zakharenko AL; Salakhutdinov NF; Lavrik OI
Clin Exp Metastasis; 2021 Oct; 38(5):431-440. PubMed ID: 34370156
[TBL] [Abstract][Full Text] [Related]
2. Influence of Tyrosyl-DNA Phosphodiesterase 1 Inhibitor on the Proapoptotic and Genotoxic Effects of Anticancer Agent Topotecan.
Chepanova AA; Zakharenko AL; Dyrkheeva NS; Chernyshova IA; Zakharova OD; Ilina ES; Luzina OA; Salakhutdinov NF; Lavrik OI
Dokl Biochem Biophys; 2023 Feb; 508(1):25-30. PubMed ID: 36653585
[TBL] [Abstract][Full Text] [Related]
3. Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Kornienko TE; Chepanova AA; Zakharenko AL; Filimonov AS; Luzina OA; Dyrkheeva NS; Nikolin VP; Popova NA; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38279210
[TBL] [Abstract][Full Text] [Related]
4. Tyrosyl-DNA Phosphodiesterase 1 Inhibitors: Usnic Acid Enamines Enhance the Cytotoxic Effect of Camptothecin.
Zakharenko A; Luzina O; Koval O; Nilov D; Gushchina I; Dyrkheeva N; Švedas V; Salakhutdinov N; Lavrik O
J Nat Prod; 2016 Nov; 79(11):2961-2967. PubMed ID: 27933897
[TBL] [Abstract][Full Text] [Related]
5. New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
Dyrkheeva NS; Filimonov AS; Luzina OA; Orlova KA; Chernyshova IA; Kornienko TE; Malakhova AA; Medvedev SP; Zakharenko AL; Ilina ES; Anarbaev RO; Naumenko KN; Klabenkova KV; Burakova EA; Stetsenko DA; Zakian SM; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768766
[TBL] [Abstract][Full Text] [Related]
6. [Antitumor Activity of the Combination of Topotecan and Tyrosyl-DNA-Phosphodiesterase 1 Inhibitor on Model Krebs-2 Mouse Ascite Carcinoma].
Dyrkheeva NS; Zakharenko AL; Novoselova ES; Chepanova AA; Popova NA; Nikolin VP; Luzina OA; Salakhutdinov NF; Ryabchikova EI; Lavrik OI
Mol Biol (Mosk); 2021; 55(2):312-317. PubMed ID: 33871444
[TBL] [Abstract][Full Text] [Related]
7. Antimetastatic Activity of Combined Topotecan and Tyrosyl-DNA Phosphodiesterase-1 Inhibitor on Modeled Lewis Lung Carcinoma.
Koldysheva EV; Men'shchikova AP; Lushnikova EL; Popova NA; Kaledin VI; Nikolin VP; Zakharenko AL; Luzina OA; Salakhutdinov NF; Lavrik OI
Bull Exp Biol Med; 2019 Mar; 166(5):661-666. PubMed ID: 30903487
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors.
Zakharova O; Luzina O; Zakharenko A; Sokolov D; Filimonov A; Dyrkheeva N; Chepanova A; Ilina E; Ilyina A; Klabenkova K; Chelobanov B; Stetsenko D; Zafar A; Eurtivong C; Reynisson J; Volcho K; Salakhutdinov N; Lavrik O
Bioorg Med Chem; 2018 Aug; 26(15):4470-4480. PubMed ID: 30076000
[TBL] [Abstract][Full Text] [Related]
9. New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Filimonov AS; Chepanova AA; Luzina OA; Zakharenko AL; Zakharova OD; Ilina ES; Dyrkheeva NS; Kuprushkin MS; Kolotaev AV; Khachatryan DS; Patel J; Leung IKH; Chand R; Ayine-Tora DM; Reynisson J; Volcho KP; Salakhutdinov NF; Lavrik OI
Molecules; 2019 Oct; 24(20):. PubMed ID: 31619021
[TBL] [Abstract][Full Text] [Related]
10. New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.
Dyrkheeva NS; Filimonov AS; Luzina OA; Zakharenko AL; Ilina ES; Malakhova AA; Medvedev SP; Reynisson J; Volcho KP; Zakian SM; Salakhutdinov NF; Lavrik OI
Biomolecules; 2021 Jul; 11(7):. PubMed ID: 34356597
[TBL] [Abstract][Full Text] [Related]
11. Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Khomenko TM; Zakharenko AL; Chepanova AA; Ilina ES; Zakharova OD; Kaledin VI; Nikolin VP; Popova NA; Korchagina DV; Reynisson J; Chand R; Ayine-Tora DM; Patel J; Leung IKH; Volcho KP; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2019 Dec; 21(1):. PubMed ID: 31878088
[TBL] [Abstract][Full Text] [Related]
12. Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
Luzina O; Filimonov A; Zakharenko A; Chepanova A; Zakharova O; Ilina E; Dyrkheeva N; Likhatskaya G; Salakhutdinov N; Lavrik O
J Nat Prod; 2020 Aug; 83(8):2320-2329. PubMed ID: 32786885
[TBL] [Abstract][Full Text] [Related]
13. The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo.
Chernyshova IA; Zakharenko AL; Kurochkin NN; Dyrkheeva NS; Kornienko TE; Popova NA; Nikolin VP; Ilina ES; Zharkov TD; Kupryushkin MS; Oslovsky VE; Drenichev MS; Lavrik OI
Molecules; 2022 Dec; 28(1):. PubMed ID: 36615517
[TBL] [Abstract][Full Text] [Related]
14. Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
Zakharenko AL; Luzina OA; Chepanova AA; Dyrkheeva NS; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982848
[TBL] [Abstract][Full Text] [Related]
15. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models.
Zakharenko AL; Luzina OA; Sokolov DN; Kaledin VI; Nikolin VP; Popova NA; Patel J; Zakharova OD; Chepanova AA; Zafar A; Reynisson J; Leung E; Leung IKH; Volcho KP; Salakhutdinov NF; Lavrik OI
Eur J Med Chem; 2019 Jan; 161():581-593. PubMed ID: 30396105
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
Yang H; Qin C; Wu M; Wang FT; Wang W; Agama K; Pommier Y; Hu DX; An LK
ChemMedChem; 2023 May; 18(10):e202200593. PubMed ID: 36932053
[TBL] [Abstract][Full Text] [Related]
17. New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
Khomenko TM; Zakharenko AL; Kornienko TE; Chepanova AA; Dyrkheeva NS; Artemova AO; Korchagina DV; Achara C; Curtis A; Reynisson J; Volcho KP; Salakhutdinov NF; Lavrik OI
Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298106
[TBL] [Abstract][Full Text] [Related]
18. Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents.
Zakharenko AL; Dyrkheeva NS; Luzina OA; Filimonov AS; Mozhaitsev ES; Malakhova AA; Medvedev SP; Zakian SM; Salakhutdinov NF; Lavrik OI
Genes (Basel); 2023 Oct; 14(10):. PubMed ID: 37895279
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer.
Hu DX; Tang WL; Zhang Y; Yang H; Wang W; Agama K; Pommier Y; An LK
J Med Chem; 2021 Jun; 64(11):7617-7629. PubMed ID: 34008967
[TBL] [Abstract][Full Text] [Related]
20. [Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo].
Kornienko TE; Zakharenko AL; Ilina ES; Chepanova AA; Zakharova OD; Dyrkheeva NS; Popova NA; Nikolin VP; Filimonov AS; Luzina OA; Salakhutdinov NF; Lavrik OI
Mol Biol (Mosk); 2023; 57(2):220-231. PubMed ID: 37000651
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
