BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 34382511)

  • 21. Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells.
    Long JS; Edwards J; Watson C; Tovey S; Mair KM; Schiff R; Natarajan V; Pyne NJ; Pyne S
    Mol Cell Biol; 2010 Aug; 30(15):3827-41. PubMed ID: 20516217
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sphingosine kinase 1 is up-regulated in colon carcinogenesis.
    Kawamori T; Osta W; Johnson KR; Pettus BJ; Bielawski J; Tanaka T; Wargovich MJ; Reddy BS; Hannun YA; Obeid LM; Zhou D
    FASEB J; 2006 Feb; 20(2):386-8. PubMed ID: 16319132
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.
    Paugh SW; Paugh BS; Rahmani M; Kapitonov D; Almenara JA; Kordula T; Milstien S; Adams JK; Zipkin RE; Grant S; Spiegel S
    Blood; 2008 Aug; 112(4):1382-91. PubMed ID: 18511810
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Short Periods of Hypoxia Upregulate Sphingosine Kinase 1 and Increase Vasodilation of Arteries to Sphingosine 1-Phosphate (S1P) via S1P
    Alganga H; Almabrouk TAM; Katwan OJ; Daly CJ; Pyne S; Pyne NJ; Kennedy S
    J Pharmacol Exp Ther; 2019 Oct; 371(1):63-74. PubMed ID: 31371480
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Role of sphingosine 1-phosphate receptors, sphingosine kinases and sphingosine in cancer and inflammation.
    Pyne NJ; McNaughton M; Boomkamp S; MacRitchie N; Evangelisti C; Martelli AM; Jiang HR; Ubhi S; Pyne S
    Adv Biol Regul; 2016 Jan; 60():151-159. PubMed ID: 26429117
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer.
    Selzner M; Bielawska A; Morse MA; Rüdiger HA; Sindram D; Hannun YA; Clavien PA
    Cancer Res; 2001 Feb; 61(3):1233-40. PubMed ID: 11221856
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway.
    Al-Khayal K; Vaali-Mohammed MA; Elwatidy M; Bin Traiki T; Al-Obeed O; Azam M; Khan Z; Abdulla M; Ahmad R
    BMC Cancer; 2020 Jul; 20(1):685. PubMed ID: 32703189
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.
    Cinq-Frais C; Coatrieux C; Grazide MH; Hannun YA; Nègre-Salvayre A; Salvayre R; Augé N
    Biochim Biophys Acta; 2013 Aug; 1831(8):1344-56. PubMed ID: 23651497
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel Dimer Derivatives of PF-543 as Potential Antitumor Agents for the Treatment of Non-Small Cell Lung Cancer.
    Kim SB; Limbu KR; Oh YS; Kim SL; Park SK; Baek DJ; Park EY
    Pharmaceutics; 2022 Sep; 14(10):. PubMed ID: 36297469
    [TBL] [Abstract][Full Text] [Related]  

  • 30. FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels.
    Chen L; Luo LF; Lu J; Li L; Liu YF; Wang J; Liu H; Song H; Jiang H; Chen SJ; Luo C; Li KK
    PLoS One; 2014; 9(7):e103033. PubMed ID: 25050888
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death.
    Qin J; Kilkus JP; Dawson G
    Biochem Biophys Res Commun; 2018 Jun; 500(3):597-602. PubMed ID: 29673590
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells.
    El-Shewy HM; Sohn M; Wilson P; Lee MH; Hammad SM; Luttrell LM; Jaffa AA
    Mol Endocrinol; 2012 May; 26(5):833-45. PubMed ID: 22422617
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate.
    Czubowicz K; Strosznajder R
    Mol Neurobiol; 2014 Aug; 50(1):26-37. PubMed ID: 24420784
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation.
    Shrestha J; Ki SH; Shin SM; Kim SW; Lee JY; Jun HS; Lee T; Kim S; Baek DJ; Park EY
    Molecules; 2018 Oct; 23(11):. PubMed ID: 30355990
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.
    Beljanski V; Lewis CS; Smith CD
    Cancer Biol Ther; 2011 Mar; 11(5):524-34. PubMed ID: 21258214
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo.
    Xun C; Chen MB; Qi L; Tie-Ning Z; Peng X; Ning L; Zhi-Xiao C; Li-Wei W
    J Exp Clin Cancer Res; 2015 Sep; 34(1):94. PubMed ID: 26337959
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids.
    Yan G; Chen S; You B; Sun J
    Cardiovasc Res; 2008 May; 78(2):308-14. PubMed ID: 18192241
    [TBL] [Abstract][Full Text] [Related]  

  • 38. FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.
    Berdyshev EV; Gorshkova I; Skobeleva A; Bittman R; Lu X; Dudek SM; Mirzapoiazova T; Garcia JG; Natarajan V
    J Biol Chem; 2009 Feb; 284(9):5467-77. PubMed ID: 19119142
    [TBL] [Abstract][Full Text] [Related]  

  • 39. An oncogenic role for sphingosine kinase 2.
    Neubauer HA; Pham DH; Zebol JR; Moretti PA; Peterson AL; Leclercq TM; Chan H; Powell JA; Pitman MR; Samuel MS; Bonder CS; Creek DJ; Gliddon BL; Pitson SM
    Oncotarget; 2016 Oct; 7(40):64886-64899. PubMed ID: 27588496
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro.
    Marvaso G; Barone A; Amodio N; Raimondi L; Agosti V; Altomare E; Scotti V; Lombardi A; Bianco R; Bianco C; Caraglia M; Tassone P; Tagliaferri P
    Cancer Biol Ther; 2014 Jun; 15(6):797-805. PubMed ID: 24657936
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.