BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 34382935)

  • 1. LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.
    Hirano KI; Hosokawa H; Koizumi M; Endo Y; Yahata T; Ando K; Hozumi K
    Elife; 2021 Aug; 10():. PubMed ID: 34382935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells.
    Koizumi M; Kama Y; Hirano KI; Endo Y; Tanaka T; Hozumi K; Hosokawa H
    J Biol Chem; 2022 Nov; 298(11):102506. PubMed ID: 36126774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conditional Immortalization of Lymphoid Progenitors via Tetracycline-Regulated
    Koniaeva E; Stahlhut M; Lange L; Sauer MG; Kustikova OS; Schambach A
    Hum Gene Ther; 2020 Feb; 31(3-4):183-198. PubMed ID: 31760808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation.
    Wang W; Meng Y; Chen Y; Yu Y; Wang H; Yang S; Sun W
    Oncogene; 2022 Aug; 41(34):4079-4090. PubMed ID: 35851847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms.
    Wiekmeijer AS; Pike-Overzet K; Brugman MH; van Eggermond MCJA; Cordes M; de Haas EFE; Li Y; Oole E; van IJcken WFJ; Egeler RM; Meijerink JP; Staal FJT
    Exp Hematol; 2016 Sep; 44(9):838-849.e9. PubMed ID: 27302866
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemia.
    Cleveland SM; Smith S; Tripathi R; Mathias EM; Goodings C; Elliott N; Peng D; El-Rifai W; Yi D; Chen X; Li L; Mullighan C; Downing JR; Love P; Davé UP
    Stem Cells; 2013 May; 31(5):882-94. PubMed ID: 23378057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.
    Goossens S; Wang J; Tremblay CS; De Medts J; T'Sas S; Nguyen T; Saw J; Haigh K; Curtis DJ; Van Vlierberghe P; Berx G; Taghon T; Haigh JJ
    Haematologica; 2019 Aug; 104(8):1608-1616. PubMed ID: 30679322
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elucidation of the role of LMO2 in human erythroid cells.
    Inoue A; Fujiwara T; Okitsu Y; Katsuoka Y; Fukuhara N; Onishi Y; Ishizawa K; Harigae H
    Exp Hematol; 2013 Dec; 41(12):1062-76.e1. PubMed ID: 24041784
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The LMO2 oncogene regulates DNA replication in hematopoietic cells.
    Sincennes MC; Humbert M; Grondin B; Lisi V; Veiga DF; Haman A; Cazaux C; Mashtalir N; Affar el B; Verreault A; Hoang T
    Proc Natl Acad Sci U S A; 2016 Feb; 113(5):1393-8. PubMed ID: 26764384
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.
    García-Ramírez I; Bhatia S; Rodríguez-Hernández G; González-Herrero I; Walter C; González de Tena-Dávila S; Parvin S; Haas O; Woessmann W; Stanulla M; Schrappe M; Dugas M; Natkunam Y; Orfao A; Domínguez V; Pintado B; Blanco O; Alonso-López D; De Las Rivas J; Martín-Lorenzo A; Jiménez R; García Criado FJ; García Cenador MB; Lossos IS; Vicente-Dueñas C; Borkhardt A; Hauer J; Sánchez-García I
    EMBO J; 2018 Jul; 37(14):. PubMed ID: 29880602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling.
    Liu Y; Wang Z; Huang D; Wu C; Li H; Zhang X; Meng B; Li Z; Zhu T; Yang S; Sun W
    Oncotarget; 2017 Feb; 8(6):9513-9524. PubMed ID: 27880729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRACHYURY directs histone acetylation to target loci during mesoderm development.
    Beisaw A; Tsaytler P; Koch F; Schmitz SU; Melissari MT; Senft AD; Wittler L; Pennimpede T; Macura K; Herrmann BG; Grote P
    EMBO Rep; 2018 Jan; 19(1):118-134. PubMed ID: 29141987
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage.
    Stanulovic VS; Cauchy P; Assi SA; Hoogenkamp M
    Nucleic Acids Res; 2017 Sep; 45(17):9874-9888. PubMed ID: 28973433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.
    Goodings C; Tripathi R; Cleveland SM; Elliott N; Guo Y; Shyr Y; Davé UP
    Leuk Res; 2015 Jan; 39(1):100-9. PubMed ID: 25499232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.
    Kim SH; Kim EJ; Hitomi M; Oh SY; Jin X; Jeon HM; Beck S; Jin X; Kim JK; Park CG; Chang SY; Yin J; Kim T; Jeon YJ; Song J; Lim YC; Lathia JD; Nakano I; Kim H
    Cell Death Differ; 2015 Sep; 22(9):1517-25. PubMed ID: 25721045
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.
    Bonadies N; Göttgens B; Calero-Nieto FJ
    PLoS One; 2015; 10(7):e0131577. PubMed ID: 26161748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
    Layer JH; Alford CE; McDonald WH; Davé UP
    Mol Cell Biol; 2016 Feb; 36(3):488-506. PubMed ID: 26598604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic dysregulation of ZEB1 is involved in LMO2-promoted T-cell acute lymphoblastic leukaemia leukaemogenesis.
    Wu C; Li J; Tian C; Shi W; Jiang H; Zhang Z; Wang H; Zhang Q; Sun W; Sun P; Xiang R; Yang S
    Biochim Biophys Acta Mol Basis Dis; 2018 Aug; 1864(8):2511-2525. PubMed ID: 29778661
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development.
    McCormack MP; Forster A; Drynan L; Pannell R; Rabbitts TH
    Mol Cell Biol; 2003 Dec; 23(24):9003-13. PubMed ID: 14645513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upstream distal regulatory elements contact the Lmo2 promoter in mouse erythroid cells.
    Bhattacharya A; Chen CY; Ho S; Mitchell JA
    PLoS One; 2012; 7(12):e52880. PubMed ID: 23285212
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.