These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
209 related articles for article (PubMed ID: 34389733)
1. The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core. Bloch NB; Wales TE; Prew MS; Levy HR; Engen JR; Walensky LD Nat Commun; 2021 Aug; 12(1):4932. PubMed ID: 34389733 [TBL] [Abstract][Full Text] [Related]
2. The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL. Parikh N; Koshy C; Dhayabaran V; Perumalsamy LR; Sowdhamini R; Sarin A BMC Cell Biol; 2007 May; 8():16. PubMed ID: 17519046 [TBL] [Abstract][Full Text] [Related]
3. Conformational rearrangements in the pro-apoptotic protein, Bax, as it inserts into mitochondria: a cellular death switch. Gahl RF; He Y; Yu S; Tjandra N J Biol Chem; 2014 Nov; 289(47):32871-82. PubMed ID: 25315775 [TBL] [Abstract][Full Text] [Related]
4. An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway. Garner TP; Reyna DE; Priyadarshi A; Chen HC; Li S; Wu Y; Ganesan YT; Malashkevich VN; Cheng EH; Gavathiotis E Mol Cell; 2016 Aug; 63(3):485-97. PubMed ID: 27425408 [TBL] [Abstract][Full Text] [Related]
6. BH3-triggered structural reorganization drives the activation of proapoptotic BAX. Gavathiotis E; Reyna DE; Davis ML; Bird GH; Walensky LD Mol Cell; 2010 Nov; 40(3):481-92. PubMed ID: 21070973 [TBL] [Abstract][Full Text] [Related]
7. Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism. Barclay LA; Wales TE; Garner TP; Wachter F; Lee S; Guerra RM; Stewart ML; Braun CR; Bird GH; Gavathiotis E; Engen JR; Walensky LD Mol Cell; 2015 Mar; 57(5):873-886. PubMed ID: 25684204 [TBL] [Abstract][Full Text] [Related]
8. BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore. Walensky LD; Gavathiotis E Trends Biochem Sci; 2011 Dec; 36(12):642-52. PubMed ID: 21978892 [TBL] [Abstract][Full Text] [Related]
9. The role of conformational heterogeneity in regulating the apoptotic activity of BAX protein. Kao TY; Tsai CJ; Lan YJ; Chiang YW Phys Chem Chem Phys; 2017 Apr; 19(14):9584-9591. PubMed ID: 28345702 [TBL] [Abstract][Full Text] [Related]
10. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Kim H; Tu HC; Ren D; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH Mol Cell; 2009 Nov; 36(3):487-99. PubMed ID: 19917256 [TBL] [Abstract][Full Text] [Related]
11. Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function. Ferrer PE; Frederick P; Gulbis JM; Dewson G; Kluck RM PLoS One; 2012; 7(3):e31510. PubMed ID: 22442658 [TBL] [Abstract][Full Text] [Related]
12. Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol. Edlich F; Banerjee S; Suzuki M; Cleland MM; Arnoult D; Wang C; Neutzner A; Tjandra N; Youle RJ Cell; 2011 Apr; 145(1):104-16. PubMed ID: 21458670 [TBL] [Abstract][Full Text] [Related]
13. Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function. Ma SB; Nguyen TN; Tan I; Ninnis R; Iyer S; Stroud DA; Menard M; Kluck RM; Ryan MT; Dewson G Cell Death Differ; 2014 Dec; 21(12):1925-35. PubMed ID: 25146925 [TBL] [Abstract][Full Text] [Related]
14. Ensemble Properties of Bax Determine Its Function. Robin AY; Iyer S; Birkinshaw RW; Sandow J; Wardak A; Luo CS; Shi M; Webb AI; Czabotar PE; Kluck RM; Colman PM Structure; 2018 Oct; 26(10):1346-1359.e5. PubMed ID: 30122452 [TBL] [Abstract][Full Text] [Related]
16. Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site. Uchime O; Dai Z; Biris N; Lee D; Sidhu SS; Li S; Lai JR; Gavathiotis E J Biol Chem; 2016 Jan; 291(1):89-102. PubMed ID: 26565029 [TBL] [Abstract][Full Text] [Related]
17. Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process. George NM; Targy N; Evans JJ; Zhang L; Luo X J Biol Chem; 2010 Jan; 285(2):1384-92. PubMed ID: 19880508 [TBL] [Abstract][Full Text] [Related]
18. Bax exists in a dynamic equilibrium between the cytosol and mitochondria to control apoptotic priming. Schellenberg B; Wang P; Keeble JA; Rodriguez-Enriquez R; Walker S; Owens TW; Foster F; Tanianis-Hughes J; Brennan K; Streuli CH; Gilmore AP Mol Cell; 2013 Mar; 49(5):959-71. PubMed ID: 23375500 [TBL] [Abstract][Full Text] [Related]