208 related articles for article (PubMed ID: 34396529)
1. Insulin-degrading enzyme: an ally against metabolic and neurodegenerative diseases.
Sousa L; Guarda M; Meneses MJ; Macedo MP; Vicente Miranda H
J Pathol; 2021 Dec; 255(4):346-361. PubMed ID: 34396529
[TBL] [Abstract][Full Text] [Related]
2. Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease.
Fernández-Gamba A; Leal MC; Morelli L; Castaño EM
Curr Pharm Des; 2009; 15(31):3644-55. PubMed ID: 19925417
[TBL] [Abstract][Full Text] [Related]
3. Insulin-degrading enzyme is activated by the C-terminus of α-synuclein.
Sharma SK; Chorell E; Wittung-Stafshede P
Biochem Biophys Res Commun; 2015 Oct; 466(2):192-5. PubMed ID: 26343304
[TBL] [Abstract][Full Text] [Related]
4. Multiple functions of insulin-degrading enzyme: a metabolic crosslight?
Tundo GR; Sbardella D; Ciaccio C; Grasso G; Gioia M; Coletta A; Polticelli F; Di Pierro D; Milardi D; Van Endert P; Marini S; Coletta M
Crit Rev Biochem Mol Biol; 2017 Oct; 52(5):554-582. PubMed ID: 28635330
[TBL] [Abstract][Full Text] [Related]
5. Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.
Sharma SK; Chorell E; Steneberg P; Vernersson-Lindahl E; Edlund H; Wittung-Stafshede P
Sci Rep; 2015 Jul; 5():12531. PubMed ID: 26228656
[TBL] [Abstract][Full Text] [Related]
6. Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus.
Tang WJ
Trends Endocrinol Metab; 2016 Jan; 27(1):24-34. PubMed ID: 26651592
[TBL] [Abstract][Full Text] [Related]
7. Degradation of amylin by insulin-degrading enzyme.
Bennett RG; Duckworth WC; Hamel FG
J Biol Chem; 2000 Nov; 275(47):36621-5. PubMed ID: 10973971
[TBL] [Abstract][Full Text] [Related]
8. The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme: a biological perspective.
de Tullio MB; Morelli L; Castaño EM
Prion; 2008; 2(2):51-6. PubMed ID: 19098445
[TBL] [Abstract][Full Text] [Related]
9. The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design.
Tundo GR; Grasso G; Persico M; Tkachuk O; Bellia F; Bocedi A; Marini S; Parravano M; Graziani G; Fattorusso C; Sbardella D
Biomolecules; 2023 Oct; 13(10):. PubMed ID: 37892174
[TBL] [Abstract][Full Text] [Related]
10. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Shen Y; Joachimiak A; Rosner MR; Tang WJ
Nature; 2006 Oct; 443(7113):870-4. PubMed ID: 17051221
[TBL] [Abstract][Full Text] [Related]
11. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.
Guo Q; Manolopoulou M; Bian Y; Schilling AB; Tang WJ
J Mol Biol; 2010 Jan; 395(2):430-43. PubMed ID: 19896952
[TBL] [Abstract][Full Text] [Related]
12. The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme.
Bellia F; Grasso G
J Mass Spectrom; 2014 Apr; 49(4):274-9. PubMed ID: 24719342
[TBL] [Abstract][Full Text] [Related]
13. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
Farris W; Mansourian S; Chang Y; Lindsley L; Eckman EA; Frosch MP; Eckman CB; Tanzi RE; Selkoe DJ; Guenette S
Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4162-7. PubMed ID: 12634421
[TBL] [Abstract][Full Text] [Related]
14. Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?
Pivovarova O; Höhn A; Grune T; Pfeiffer AF; Rudovich N
Ann Med; 2016 Dec; 48(8):614-624. PubMed ID: 27320287
[TBL] [Abstract][Full Text] [Related]
15. Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation.
Cordes CM; Bennett RG; Siford GL; Hamel FG
Biochem Pharmacol; 2009 Mar; 77(6):1064-73. PubMed ID: 19154729
[TBL] [Abstract][Full Text] [Related]
16. Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer's disease and brain aging.
Corraliza-Gomez M; Bermejo T; Lilue J; Rodriguez-Iglesias N; Valero J; Cozar-Castellano I; Arranz E; Sanchez D; Ganfornina MD
J Neuroinflammation; 2023 Oct; 20(1):233. PubMed ID: 37817156
[TBL] [Abstract][Full Text] [Related]
17. Insulin-Degrading Enzyme in the Fight against Alzheimer's Disease.
Kurochkin IV; Guarnera E; Berezovsky IN
Trends Pharmacol Sci; 2018 Jan; 39(1):49-58. PubMed ID: 29132916
[TBL] [Abstract][Full Text] [Related]
18. Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang Z; Liang WG; Bailey LJ; Tan YZ; Wei H; Wang A; Farcasanu M; Woods VA; McCord LA; Lee D; Shang W; Deprez-Poulain R; Deprez B; Liu DR; Koide A; Koide S; Kossiakoff AA; Li S; Carragher B; Potter CS; Tang WJ
Elife; 2018 Mar; 7():. PubMed ID: 29596046
[TBL] [Abstract][Full Text] [Related]
19. Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.
Zhao L; Teter B; Morihara T; Lim GP; Ambegaokar SS; Ubeda OJ; Frautschy SA; Cole GM
J Neurosci; 2004 Dec; 24(49):11120-6. PubMed ID: 15590928
[TBL] [Abstract][Full Text] [Related]
20. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.
Qiu WQ; Walsh DM; Ye Z; Vekrellis K; Zhang J; Podlisny MB; Rosner MR; Safavi A; Hersh LB; Selkoe DJ
J Biol Chem; 1998 Dec; 273(49):32730-8. PubMed ID: 9830016
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
