237 related articles for article (PubMed ID: 34403210)
61. Beta-secretase (BACE) as a drug target for Alzheimer's disease.
Vassar R
Adv Drug Deliv Rev; 2002 Dec; 54(12):1589-602. PubMed ID: 12453676
[TBL] [Abstract][Full Text] [Related]
62. BACE1 in Alzheimer's disease.
Sathya M; Premkumar P; Karthick C; Moorthi P; Jayachandran KS; Anusuyadevi M
Clin Chim Acta; 2012 Dec; 414():171-8. PubMed ID: 22926063
[TBL] [Abstract][Full Text] [Related]
63. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
[TBL] [Abstract][Full Text] [Related]
64. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
[TBL] [Abstract][Full Text] [Related]
65. Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation.
Lim JR; Lee HJ; Jung YH; Kim JS; Chae CW; Kim SY; Han HJ
Cell Commun Signal; 2020 Aug; 18(1):123. PubMed ID: 32787872
[TBL] [Abstract][Full Text] [Related]
66. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
67. Lysophosphatidic acid induces increased BACE1 expression and Aβ formation.
Shi J; Dong Y; Cui MZ; Xu X
Biochim Biophys Acta; 2013 Jan; 1832(1):29-38. PubMed ID: 23036978
[TBL] [Abstract][Full Text] [Related]
68. Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.
Chen Y; Zhou K; Wang R; Liu Y; Kwak YD; Ma T; Thompson RC; Zhao Y; Smith L; Gasparini L; Luo Z; Xu H; Liao FF
Proc Natl Acad Sci U S A; 2009 Mar; 106(10):3907-12. PubMed ID: 19237574
[TBL] [Abstract][Full Text] [Related]
69. Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration.
Schaefer PM; von Einem B; Walther P; Calzia E; von Arnim CA
PLoS One; 2016; 11(12):e0168157. PubMed ID: 28005987
[TBL] [Abstract][Full Text] [Related]
70. Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
Gong B; Pan Y; Vempati P; Zhao W; Knable L; Ho L; Wang J; Sastre M; Ono K; Sauve AA; Pasinetti GM
Neurobiol Aging; 2013 Jun; 34(6):1581-8. PubMed ID: 23312803
[TBL] [Abstract][Full Text] [Related]
71. Increasing ERK phosphorylation by inhibition of p38 activity protects against cadmium-induced apoptotic cell death through ERK/Drp1/p38 signaling axis in spermatocyte-derived GC-2spd cells.
Seong JB; Bae YC; Lee HS; Huh JW; Lee SR; Lee HJ; Lee DS
Toxicol Appl Pharmacol; 2019 Dec; 384():114797. PubMed ID: 31676320
[TBL] [Abstract][Full Text] [Related]
72. Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY; Xiang XJ; Song L; Chen J; Luo B; Wen QX; Zhong BR; Zhou GF; Deng XJ; Ma YL; Hu LT; Chen GJ
J Neurochem; 2021 May; 157(4):1351-1365. PubMed ID: 32920833
[TBL] [Abstract][Full Text] [Related]
73. Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS.
Georgievska B; Gustavsson S; Lundkvist J; Neelissen J; Eketjäll S; Ramberg V; Bueters T; Agerman K; Juréus A; Svensson S; Berg S; Fälting J; Lendahl U
J Neurochem; 2015 Feb; 132(4):477-86. PubMed ID: 25156639
[TBL] [Abstract][Full Text] [Related]
74. Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases.
Cai Z; Wang C; He W; Chen Y
Curr Alzheimer Res; 2018; 15(11):1045-1052. PubMed ID: 29962345
[TBL] [Abstract][Full Text] [Related]
75. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Manczak M; Reddy PH
Hum Mol Genet; 2012 Jun; 21(11):2538-47. PubMed ID: 22367970
[TBL] [Abstract][Full Text] [Related]
76. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
O'Connor T; Sadleir KR; Maus E; Velliquette RA; Zhao J; Cole SL; Eimer WA; Hitt B; Bembinster LA; Lammich S; Lichtenthaler SF; Hébert SS; De Strooper B; Haass C; Bennett DA; Vassar R
Neuron; 2008 Dec; 60(6):988-1009. PubMed ID: 19109907
[TBL] [Abstract][Full Text] [Related]
77. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
78. [Effects of hypoxia on the survival and Alzheimer's disease-related protein expression in HEK293 cells stably expression APP695 protein].
Qiao M; Huang X; He YL; Zhou YZ; Han X; Zhu LL; Fan M
Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2016 Feb; 32(2):106-109. PubMed ID: 29931858
[TBL] [Abstract][Full Text] [Related]
79. Lys(203) and Lys(382) are essential for the proteasomal degradation of BACE1.
Wang R; Ying Z; Zhao J; Zhang Y; Wang R; Lu H; Deng Y; Song W; Qing H
Curr Alzheimer Res; 2012 Jun; 9(5):606-15. PubMed ID: 22299711
[TBL] [Abstract][Full Text] [Related]
80. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.
Zhang XM; Cai Y; Xiong K; Cai H; Luo XG; Feng JC; Clough RW; Struble RG; Patrylo PR; Yan XX
Eur J Neurosci; 2009 Dec; 30(12):2271-83. PubMed ID: 20092570
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]