169 related articles for article (PubMed ID: 34405966)
1. The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation.
El Oumeiri B; van de Borne P; Hubesch G; Herpain A; Annoni F; Jespers P; Stefanidis C; Mc Entee K; Vanden Eynden F
Physiol Rep; 2021 Aug; 9(16):e14988. PubMed ID: 34405966
[TBL] [Abstract][Full Text] [Related]
2. Effects of the cardiac myosin activator Omecamtiv-mecarbil on severe chronic aortic regurgitation in Wistar rats.
El-Oumeiri B; Mc Entee K; Annoni F; Herpain A; Vanden Eynden F; Jespers P; Van Nooten G; van de Borne P
BMC Cardiovasc Disord; 2018 May; 18(1):99. PubMed ID: 29783950
[TBL] [Abstract][Full Text] [Related]
3. Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study.
Teerlink JR; Clarke CP; Saikali KG; Lee JH; Chen MM; Escandon RD; Elliott L; Bee R; Habibzadeh MR; Goldman JH; Schiller NB; Malik FI; Wolff AA
Lancet; 2011 Aug; 378(9792):667-75. PubMed ID: 21856480
[TBL] [Abstract][Full Text] [Related]
4. The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial.
Cleland JG; Teerlink JR; Senior R; Nifontov EM; Mc Murray JJ; Lang CC; Tsyrlin VA; Greenberg BH; Mayet J; Francis DP; Shaburishvili T; Monaghan M; Saltzberg M; Neyses L; Wasserman SM; Lee JH; Saikali KG; Clarke CP; Goldman JH; Wolff AA; Malik FI
Lancet; 2011 Aug; 378(9792):676-83. PubMed ID: 21856481
[TBL] [Abstract][Full Text] [Related]
5. Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure: The ATOMIC-AHF Study.
Teerlink JR; Felker GM; McMurray JJV; Ponikowski P; Metra M; Filippatos GS; Ezekowitz JA; Dickstein K; Cleland JGF; Kim JB; Lei L; Knusel B; Wolff AA; Malik FI; Wasserman SM;
J Am Coll Cardiol; 2016 Mar; 67(12):1444-1455. PubMed ID: 27012405
[TBL] [Abstract][Full Text] [Related]
6. Myosin Activator Omecamtiv Mecarbil Increases Myocardial Oxygen Consumption and Impairs Cardiac Efficiency Mediated by Resting Myosin ATPase Activity.
Bakkehaug JP; Kildal AB; Engstad ET; Boardman N; Næsheim T; Rønning L; Aasum E; Larsen TS; Myrmel T; How OJ
Circ Heart Fail; 2015 Jul; 8(4):766-75. PubMed ID: 26025342
[TBL] [Abstract][Full Text] [Related]
7. Omecamtiv mecarbil: a new cardiac myosin activator for the treatment of heart failure.
Liu LC; Dorhout B; van der Meer P; Teerlink JR; Voors AA
Expert Opin Investig Drugs; 2016; 25(1):117-27. PubMed ID: 26587768
[TBL] [Abstract][Full Text] [Related]
8. Omecamtiv mecarbil treatment improves post-resuscitation cardiac function and neurological outcome in a rat model.
Wu SN; Tsai MS; Huang CH; Chen WJ
PLoS One; 2022; 17(2):e0264165. PubMed ID: 35176110
[TBL] [Abstract][Full Text] [Related]
9. Improvement of cardiac function by a cardiac Myosin activator in conscious dogs with systolic heart failure.
Shen YT; Malik FI; Zhao X; Depre C; Dhar SK; Abarzúa P; Morgans DJ; Vatner SF
Circ Heart Fail; 2010 Jul; 3(4):522-7. PubMed ID: 20498236
[TBL] [Abstract][Full Text] [Related]
10. Detection of soluble suppression of tumorigenicity 2 and N-terminal B-type natriuretic peptide in a rat model of aortic regurgitation: differential responses to omecamtiv mecarbil.
El Oumeiri B; van de Borne P; Hubesch G; Jespers P; Dewachter L; Stefanidis C; Mc Entee K; Vanden Eynden F
J Basic Clin Physiol Pharmacol; 2022 Nov; 33(6):743-750. PubMed ID: 36215707
[TBL] [Abstract][Full Text] [Related]
11. Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure.
Teerlink JR; Diaz R; Felker GM; McMurray JJV; Metra M; Solomon SD; Adams KF; Anand I; Arias-Mendoza A; Biering-Sørensen T; Böhm M; Bonderman D; Cleland JGF; Corbalan R; Crespo-Leiro MG; Dahlström U; Echeverria LE; Fang JC; Filippatos G; Fonseca C; Goncalvesova E; Goudev AR; Howlett JG; Lanfear DE; Li J; Lund M; Macdonald P; Mareev V; Momomura SI; O'Meara E; Parkhomenko A; Ponikowski P; Ramires FJA; Serpytis P; Sliwa K; Spinar J; Suter TM; Tomcsanyi J; Vandekerckhove H; Vinereanu D; Voors AA; Yilmaz MB; Zannad F; Sharpsten L; Legg JC; Varin C; Honarpour N; Abbasi SA; Malik FI; Kurtz CE;
N Engl J Med; 2021 Jan; 384(2):105-116. PubMed ID: 33185990
[TBL] [Abstract][Full Text] [Related]
12. Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial.
Teerlink JR; Felker GM; McMurray JJ; Solomon SD; Adams KF; Cleland JG; Ezekowitz JA; Goudev A; Macdonald P; Metra M; Mitrovic V; Ponikowski P; Serpytis P; Spinar J; Tomcsányi J; Vandekerckhove HJ; Voors AA; Monsalvo ML; Johnston J; Malik FI; Honarpour N;
Lancet; 2016 Dec; 388(10062):2895-2903. PubMed ID: 27914656
[TBL] [Abstract][Full Text] [Related]
13. Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial.
Lewis GD; Voors AA; Cohen-Solal A; Metra M; Whellan DJ; Ezekowitz JA; Böhm M; Teerlink JR; Docherty KF; Lopes RD; Divanji PH; Heitner SB; Kupfer S; Malik FI; Meng L; Wohltman A; Felker GM
JAMA; 2022 Jul; 328(3):259-269. PubMed ID: 35852527
[TBL] [Abstract][Full Text] [Related]
14. Omecamtiv mecarbil evokes diastolic dysfunction and leads to periodic electromechanical alternans.
Fülöp GÁ; Oláh A; Csipo T; Kovács Á; Pórszász R; Veress R; Horváth B; Nagy L; Bódi B; Fagyas M; Helgadottir SL; Bánhegyi V; Juhász B; Bombicz M; Priksz D; Nanasi P; Merkely B; Édes I; Csanádi Z; Papp Z; Radovits T; Tóth A
Basic Res Cardiol; 2021 Apr; 116(1):24. PubMed ID: 33844095
[TBL] [Abstract][Full Text] [Related]
15. Direct Myosin Activation by Omecamtiv Mecarbil for Heart Failure with Reduced Ejection Fraction.
Psotka MA; Teerlink JR
Handb Exp Pharmacol; 2017; 243():465-490. PubMed ID: 28315072
[TBL] [Abstract][Full Text] [Related]
16. Omecamtiv mecarbil attenuates length-tension relationship in healthy rat myocardium and preserves it in monocrotaline-induced pulmonary heart failure.
Lookin O; Kuznetsov D; Protsenko Y
Clin Exp Pharmacol Physiol; 2022 Jan; 49(1):84-93. PubMed ID: 34459025
[TBL] [Abstract][Full Text] [Related]
17. Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations.
Rhoden A; Schulze T; Pietsch N; Christ T; Hansen A; Eschenhagen T
Am J Physiol Heart Circ Physiol; 2022 Mar; 322(3):H373-H385. PubMed ID: 35030072
[TBL] [Abstract][Full Text] [Related]
18. Effects of Omecamtiv Mecarbil on Symptoms and Health-Related Quality of Life in Patients With Chronic Heart Failure: Results From the COSMIC-HF Study.
Felker GM; Solomon SD; McMurray JJV; Cleland JGF; Abbasi SA; Malik FI; Zhang H; Globe G; Teerlink JR;
Circ Heart Fail; 2020 Dec; 13(12):e007814. PubMed ID: 33176437
[TBL] [Abstract][Full Text] [Related]
19. Frequency-dependent effects of omecamtiv mecarbil on cell shortening of isolated canine ventricular cardiomyocytes.
Horváth B; Szentandrássy N; Veress R; Almássy J; Magyar J; Bányász T; Tóth A; Papp Z; Nánási PP
Naunyn Schmiedebergs Arch Pharmacol; 2017 Dec; 390(12):1239-1246. PubMed ID: 28940010
[TBL] [Abstract][Full Text] [Related]
20. Omecamtiv Mecarbil: A Myosin Motor Activator Agent with Promising Clinical Performance and New in vitro Results.
Nanasi P; Komaromi I; Gaburjakova M; Almassy J
Curr Med Chem; 2018; 25(15):1720-1728. PubMed ID: 29278207
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
