These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 34407950)

  • 21. Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice.
    Xie P; Jia L; Ma Y; Ou J; Miao H; Wang N; Guo F; Yazdanyar A; Jiang XC; Yu L
    Arterioscler Thromb Vasc Biol; 2013 May; 33(5):920-5. PubMed ID: 23471229
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inhibition of Niemann-Pick C1-Like 1 by Ezetimibe Reduces Dietary 5β,6β-Epoxycholesterol Absorption in Rats.
    Shirouchi B; Furukawa Y; Nakamura Y; Kawauchi A; Imaizumi K; Oku H; Sato M
    Cardiovasc Drugs Ther; 2019 Feb; 33(1):35-44. PubMed ID: 30671747
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.
    Jia L; Betters JL; Yu L
    Annu Rev Physiol; 2011; 73():239-59. PubMed ID: 20809793
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Extracellular loop C of NPC1L1 is important for binding to ezetimibe.
    Weinglass AB; Kohler M; Schulte U; Liu J; Nketiah EO; Thomas A; Schmalhofer W; Williams B; Bildl W; McMasters DR; Dai K; Beers L; McCann ME; Kaczorowski GJ; Garcia ML
    Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11140-5. PubMed ID: 18682566
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The structure and function of Niemann-Pick C1-like 1 protein.
    Yu L
    Curr Opin Lipidol; 2008 Jun; 19(3):263-9. PubMed ID: 18460917
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption.
    Zhang R; Liu W; Zeng J; Meng J; Jiang H; Wang J; Xing D
    Eur J Med Chem; 2022 Feb; 230():114111. PubMed ID: 35063734
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
    Knöpfel M; Davies JP; Duong PT; Kvaernø L; Carreira EM; Phillips MC; Ioannou YA; Hauser H
    Biochim Biophys Acta; 2007 Sep; 1771(9):1140-7. PubMed ID: 17689140
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [Progress of Niemann-Pick type C1 Like 1 on cholesterol metabolism].
    Yang JY; Hu YW; Zhang P; Zheng L; Wang Q
    Sheng Li Xue Bao; 2012 Dec; 64(6):721-8. PubMed ID: 23258338
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.
    Xie 谢畅 C; Zhou 周章森 ZS; Li 李钠 N; Bian 卞艳 Y; Wang 王永建 YJ; Wang 王丽娟 LJ; Li 李伯良 BL; Song 宋保亮 BL
    J Lipid Res; 2012 Oct; 53(10):2092-2101. PubMed ID: 22811412
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats.
    Ontawong A; Duangjai A; Muanprasat C; Pasachan T; Pongchaidecha A; Amornlerdpison D; Srimaroeng C
    Phytomedicine; 2019 Jan; 52():187-197. PubMed ID: 30599898
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Ezetimibe-sensitive cholesterol uptake by NPC1L1 protein does not require endocytosis.
    Johnson TA; Pfeffer SR
    Mol Biol Cell; 2016 Jun; 27(11):1845-52. PubMed ID: 27075173
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
    Altmann SW; Davis HR; Zhu LJ; Yao X; Hoos LM; Tetzloff G; Iyer SP; Maguire M; Golovko A; Zeng M; Wang L; Murgolo N; Graziano MP
    Science; 2004 Feb; 303(5661):1201-4. PubMed ID: 14976318
    [TBL] [Abstract][Full Text] [Related]  

  • 33. An Approach to Improve Intestinal Absorption of Poorly Absorbed Water-Insoluble Components via Niemann-Pick C1-Like 1.
    Takekawa Y; Sato Y; Yamaki Y; Imai M; Noto K; Sumi M; Takekuma Y; Iseki K; Sugawara M
    Biol Pharm Bull; 2016; 39(3):301-7. PubMed ID: 26934923
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Niemann-Pick C1-Like 1 and cholesterol uptake.
    Wang LJ; Song BL
    Biochim Biophys Acta; 2012 Jul; 1821(7):964-72. PubMed ID: 22480541
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Impact of micelle characteristics on cholesterol absorption and ezetimibe inhibition: Insights from Niemann-Pick C1-like 1 binding and molecular structure.
    Aizawa H
    J Liposome Res; 2024 Sep; 34(3):386-398. PubMed ID: 37905576
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption.
    Wang J; Chu BB; Ge L; Li BL; Yan Y; Song BL
    J Lipid Res; 2009 Aug; 50(8):1653-62. PubMed ID: 19325169
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine.
    Adams MR; Konaniah E; Cash JG; Hui DY
    Am J Physiol Gastrointest Liver Physiol; 2011 Jan; 300(1):G164-9. PubMed ID: 21071508
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).
    Garcia-Calvo M; Lisnock J; Bull HG; Hawes BE; Burnett DA; Braun MP; Crona JH; Davis HR; Dean DC; Detmers PA; Graziano MP; Hughes M; Macintyre DE; Ogawa A; O'neill KA; Iyer SP; Shevell DE; Smith MM; Tang YS; Makarewicz AM; Ujjainwalla F; Altmann SW; Chapman KT; Thornberry NA
    Proc Natl Acad Sci U S A; 2005 Jun; 102(23):8132-7. PubMed ID: 15928087
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.
    Zhang JH; Ge L; Qi W; Zhang L; Miao HH; Li BL; Yang M; Song BL
    J Biol Chem; 2011 Jul; 286(28):25088-97. PubMed ID: 21602275
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
    Saha P; Shumate JL; Caldwell JG; Elghobashi-Meinhardt N; Lu A; Zhang L; Olsson NE; Elias JE; Pfeffer SR
    Elife; 2020 May; 9():. PubMed ID: 32410728
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.