247 related articles for article (PubMed ID: 34415396)
1. Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle.
Park JM; Josan S; Hurd RE; Graham J; Havel PJ; Bendahan D; Mayer D; Chung Y; Spielman DM; Jue T
Pflugers Arch; 2021 Nov; 473(11):1761-1773. PubMed ID: 34415396
[TBL] [Abstract][Full Text] [Related]
2. Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats.
Abdel-aleem S; Karim AM; Zarouk WA; Taylor DA; el-Awady MK; Lowe JE
Horm Metab Res; 1997 Sep; 29(9):430-5. PubMed ID: 9370110
[TBL] [Abstract][Full Text] [Related]
3. Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.
Rahimi Y; Camporez JP; Petersen MC; Pesta D; Perry RJ; Jurczak MJ; Cline GW; Shulman GI
Proc Natl Acad Sci U S A; 2014 Nov; 111(46):16508-13. PubMed ID: 25368185
[TBL] [Abstract][Full Text] [Related]
4. The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.
Schroeder MA; Atherton HJ; Dodd MS; Lee P; Cochlin LE; Radda GK; Clarke K; Tyler DJ
Circ Cardiovasc Imaging; 2012 Mar; 5(2):201-9. PubMed ID: 22238215
[TBL] [Abstract][Full Text] [Related]
5. Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide.
Kerbey AL; Randle PJ; Cooper RH; Whitehouse S; Pask HT; Denton RM
Biochem J; 1976 Feb; 154(2):327-48. PubMed ID: 180974
[TBL] [Abstract][Full Text] [Related]
6. Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle.
Park JM; Josan S; Mayer D; Hurd RE; Chung Y; Bendahan D; Spielman DM; Jue T
J Exp Biol; 2015 Oct; 218(Pt 20):3308-18. PubMed ID: 26347554
[TBL] [Abstract][Full Text] [Related]
7. Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake.
Small L; Brandon AE; Quek LE; Krycer JR; James DE; Turner N; Cooney GJ
Am J Physiol Endocrinol Metab; 2018 Aug; 315(2):E258-E266. PubMed ID: 29406780
[TBL] [Abstract][Full Text] [Related]
8. Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
Lloyd S; Brocks C; Chatham JC
Am J Physiol Heart Circ Physiol; 2003 Jul; 285(1):H163-72. PubMed ID: 12793977
[TBL] [Abstract][Full Text] [Related]
9. Real-time hyperpolarized
Sharma G; Wu CY; Wynn RM; Gui W; Malloy CR; Sherry AD; Chuang DT; Khemtong C
Sci Rep; 2019 Nov; 9(1):16480. PubMed ID: 31712597
[TBL] [Abstract][Full Text] [Related]
10. Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo.
McAllister A; Allison SP; Randle PJ
Biochem J; 1973 Aug; 134(4):1067-81. PubMed ID: 4762752
[TBL] [Abstract][Full Text] [Related]
11. A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.
Wu CY; Satapati S; Gui W; Wynn RM; Sharma G; Lou M; Qi X; Burgess SC; Malloy C; Khemtong C; Sherry AD; Chuang DT; Merritt ME
J Biol Chem; 2018 Jun; 293(25):9604-9613. PubMed ID: 29739849
[TBL] [Abstract][Full Text] [Related]
12. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
Min BK; Park S; Kang HJ; Kim DW; Ham HJ; Ha CM; Choi BJ; Lee JY; Oh CJ; Yoo EK; Kim HE; Kim BG; Jeon JH; Hyeon DY; Hwang D; Kim YH; Lee CH; Lee T; Kim JW; Choi YK; Park KG; Chawla A; Lee J; Harris RA; Lee IK
Front Immunol; 2019; 10():944. PubMed ID: 31134063
[TBL] [Abstract][Full Text] [Related]
13. Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.
Warren BE; Lou PH; Lucchinetti E; Zhang L; Clanachan AS; Affolter A; Hersberger M; Zaugg M; Lemieux H
Am J Physiol Endocrinol Metab; 2014 Mar; 306(6):E658-67. PubMed ID: 24425766
[TBL] [Abstract][Full Text] [Related]
14. Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle: a 13C nuclear magnetic resonance study.
Jucker BM; Cline GW; Barucci N; Shulman GI
Diabetes; 1999 Jan; 48(1):134-40. PubMed ID: 9892234
[TBL] [Abstract][Full Text] [Related]
15. Use of hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat.
Hu S; Yoshihara HA; Bok R; Zhou J; Zhu M; Kurhanewicz J; Vigneron DB
Magn Reson Imaging; 2012 Dec; 30(10):1367-72. PubMed ID: 22819176
[TBL] [Abstract][Full Text] [Related]
16. Regulating mitochondrial metabolism by targeting pyruvate dehydrogenase with dichloroacetate, a metabolic messenger.
Schoenmann N; Tannenbaum N; Hodgeman RM; Raju RP
Biochim Biophys Acta Mol Basis Dis; 2023 Oct; 1869(7):166769. PubMed ID: 37263447
[TBL] [Abstract][Full Text] [Related]
17. Fatty acid regulation of glucose metabolism in the intact beating rat heart assessed by carbon-13 NMR spectroscopy: the critical role of pyruvate dehydrogenase.
Weiss RG; Chacko VP; Gerstenblith G
J Mol Cell Cardiol; 1989 May; 21(5):469-78. PubMed ID: 2528640
[TBL] [Abstract][Full Text] [Related]
18. Effect of insulin on ketogenesis and fatty acid synthesis in rat hepatocytes incubated with dichloroacetate.
Agius L; Vaartjes WJ
Biochim Biophys Acta; 1985 Mar; 844(3):393-9. PubMed ID: 3918587
[TBL] [Abstract][Full Text] [Related]
19. Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle.
Jørgensen W; Rud KA; Mortensen OH; Frandsen L; Grunnet N; Quistorff B
Physiol Rep; 2017 Mar; 5(6):. PubMed ID: 28330953
[TBL] [Abstract][Full Text] [Related]
20. Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.
Savic D; Ball V; Holzner L; Hauton D; Timm KN; Curtis MK; Heather LC; Tyler DJ
NMR Biomed; 2021 Apr; 34(4):e4471. PubMed ID: 33458907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
