131 related articles for article (PubMed ID: 34416096)
1. Design, synthesis, and biological evaluation of benzo[b]thiophene 1,1-dioxide derivatives as potent STAT3 inhibitors.
Li WZ; Xi HZ; Wang YJ; Ma HB; Cheng ZQ; Yang Y; Wu ML; Liu TM; Yang W; Wang Q; Liao MY; Xia Y; Zhang YW
Chem Biol Drug Des; 2021 Nov; 98(5):835-849. PubMed ID: 34416096
[TBL] [Abstract][Full Text] [Related]
2. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
Cai G; Yu W; Song D; Zhang W; Guo J; Zhu J; Ren Y; Kong L
Eur J Med Chem; 2019 Jul; 174():236-251. PubMed ID: 31048139
[TBL] [Abstract][Full Text] [Related]
3. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.
Gao D; Jin N; Fu Y; Zhu Y; Wang Y; Wang T; Chen Y; Zhang M; Xiao Q; Huang M; Li Y
Eur J Med Chem; 2021 Apr; 216():113333. PubMed ID: 33689932
[TBL] [Abstract][Full Text] [Related]
4. Antagonizing STAT3 activation with benzo[b]thiophene 1, 1-dioxide based small molecules.
Zhang W; Ma T; Li S; Yang Y; Guo J; Yu W; Kong L
Eur J Med Chem; 2017 Jan; 125():538-550. PubMed ID: 27718470
[TBL] [Abstract][Full Text] [Related]
5. Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.
Qiu HY; Zhu X; Luo YL; Lin HY; Tang CY; Qi JL; Pang YJ; Yang RW; Lu GH; Wang XM; Yang YH
Sci Rep; 2017 Jun; 7(1):2863. PubMed ID: 28588262
[TBL] [Abstract][Full Text] [Related]
6. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study.
Wang F; Feng KR; Zhao JY; Zhang JW; Shi XW; Zhou J; Gao D; Lin GQ; Tian P
Bioorg Med Chem; 2020 Dec; 28(24):115822. PubMed ID: 33126089
[TBL] [Abstract][Full Text] [Related]
7. Discovery of monocarbonyl curcumin-BTP hybrids as STAT3 inhibitors for drug-sensitive and drug-resistant breast cancer therapy.
Zhang W; Guo J; Li S; Ma T; Xu D; Han C; Liu F; Yu W; Kong L
Sci Rep; 2017 Apr; 7():46352. PubMed ID: 28397855
[TBL] [Abstract][Full Text] [Related]
8. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.
Zhang L; Liu P; Jiang Y; Fan D; He X; Zhang J; Luo B; Sui J; Luo Y; Fu X; Yang T
Eur J Med Chem; 2024 Jun; 272():116448. PubMed ID: 38704936
[TBL] [Abstract][Full Text] [Related]
9. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
Zhao W; Jaganathan S; Turkson J
J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
[TBL] [Abstract][Full Text] [Related]
10. Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).
Chen H; Yang Z; Ding C; Xiong A; Wild C; Wang L; Ye N; Cai G; Flores RM; Ding Y; Shen Q; Zhou J
Eur J Med Chem; 2014 Jul; 82():195-203. PubMed ID: 24904966
[TBL] [Abstract][Full Text] [Related]
11. 4-Carbonyl-2,6-dibenzylidenecyclohexanone derivatives as small molecule inhibitors of STAT3 signaling pathway.
Ji P; Yuan C; Ma S; Fan J; Fu W; Qiao C
Bioorg Med Chem; 2016 Dec; 24(23):6174-6182. PubMed ID: 27816267
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.
Wang X; He Q; Wu K; Guo T; Du X; Zhang H; Fang L; Zheng N; Zhang Q; Ye F
Eur J Med Chem; 2019 Oct; 179():218-232. PubMed ID: 31254923
[TBL] [Abstract][Full Text] [Related]
13. Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.
Page BD; Croucher DC; Li ZH; Haftchenary S; Jimenez-Zepeda VH; Atkinson J; Spagnuolo PA; Wong YL; Colaguori R; Lewis AM; Schimmer AD; Trudel S; Gunning PT
J Med Chem; 2013 Sep; 56(18):7190-200. PubMed ID: 23968501
[TBL] [Abstract][Full Text] [Related]
14. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy.
Feng KR; Wang F; Shi XW; Tan YX; Zhao JY; Zhang JW; Li QH; Lin GQ; Gao D; Tian P
Eur J Med Chem; 2020 Sep; 201():112428. PubMed ID: 32603980
[TBL] [Abstract][Full Text] [Related]
16. Novel 2-Carbonylbenzo[b]thiophene 1,1-Dioxide Derivatives as Potent Inhibitors of STAT3 Signaling Pathway.
Ji P; Xu X; Ma S; Fan J; Zhou Q; Mao X; Qiao C
ACS Med Chem Lett; 2015 Sep; 6(9):1010-4. PubMed ID: 26396689
[TBL] [Abstract][Full Text] [Related]
17. Chemical probes that competitively and selectively inhibit Stat3 activation.
Xu X; Kasembeli MM; Jiang X; Tweardy BJ; Tweardy DJ
PLoS One; 2009; 4(3):e4783. PubMed ID: 19274102
[TBL] [Abstract][Full Text] [Related]
18. Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3).
Brambilla L; Genini D; Laurini E; Merulla J; Perez L; Fermeglia M; Carbone GM; Pricl S; Catapano CV
Mol Oncol; 2015 Jun; 9(6):1194-206. PubMed ID: 25777967
[TBL] [Abstract][Full Text] [Related]
19. Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.
Page BD; Fletcher S; Yue P; Li Z; Zhang X; Sharmeen S; Datti A; Wrana JL; Trudel S; Schimmer AD; Turkson J; Gunning PT
Bioorg Med Chem Lett; 2011 Sep; 21(18):5605-9. PubMed ID: 21788134
[TBL] [Abstract][Full Text] [Related]
20. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells.
Seo HS; Ku JM; Choi HS; Choi YK; Woo JK; Kim M; Kim I; Na CH; Hur H; Jang BH; Shin YC; Ko SG
Oncol Rep; 2016 Jul; 36(1):31-42. PubMed ID: 27175602
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
