BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 34417575)

  • 1. All-trans retinoic acid impairs glucose-stimulated insulin secretion by activating the RXR/SREBP-1c/UCP2 pathway.
    Yang HY; Liu M; Sheng Y; Zhu L; Jin MM; Jiang TX; Yang L; Liu PH; Liu XD; Liu L
    Acta Pharmacol Sin; 2022 Jun; 43(6):1441-1452. PubMed ID: 34417575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells.
    Oberkofler H; Hafner M; Felder T; Krempler F; Patsch W
    J Mol Med (Berl); 2009 Mar; 87(3):299-306. PubMed ID: 19082571
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action.
    Li R; Chen W; Li Y; Zhang Y; Chen G
    Biochem Biophys Res Commun; 2011 Mar; 406(2):268-72. PubMed ID: 21316346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sterol regulatory element-binding protein-1c knockdown protected INS-1E cells from lipotoxicity.
    Li J; Liu X; Ran X; Chen J; Li X; Wu W; Huang H; Huang H; Long Y; Liang J; Cheng J; Tian H
    Diabetes Obes Metab; 2010 Jan; 12(1):35-46. PubMed ID: 19758361
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retinoid-X receptors and the effects of 9-cis-retinoic acid on insulin secretion from RINm5F cells.
    Chertow BS; Driscoll HK; Goking NQ; Primerano D; Cordle MB; Matthews KA
    Metabolism; 1997 Jun; 46(6):656-60. PubMed ID: 9186301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.
    Yoshikawa T; Shimano H; Amemiya-Kudo M; Yahagi N; Hasty AH; Matsuzaka T; Okazaki H; Tamura Y; Iizuka Y; Ohashi K; Osuga J; Harada K; Gotoda T; Kimura S; Ishibashi S; Yamada N
    Mol Cell Biol; 2001 May; 21(9):2991-3000. PubMed ID: 11287605
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells.
    Shao S; Liu Z; Yang Y; Zhang M; Yu X
    J Cell Biochem; 2010 Oct; 111(3):634-42. PubMed ID: 20589757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silibinin protects β cells from glucotoxicity through regulation of the Insig-1/SREBP-1c pathway.
    Chen K; Zhao L; He H; Wan X; Wang F; Mo Z
    Int J Mol Med; 2014 Oct; 34(4):1073-80. PubMed ID: 25109869
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of retinoids and thiazolidinediones on proliferation, insulin release, insulin mRNA, GLUT 2 transporter protein and mRNA of INS-1 cells.
    Blumentrath J; Neye H; Verspohl EJ
    Cell Biochem Funct; 2001 Sep; 19(3):159-69. PubMed ID: 11494305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.
    Kato T; Shimano H; Yamamoto T; Ishikawa M; Kumadaki S; Matsuzaka T; Nakagawa Y; Yahagi N; Nakakuki M; Hasty AH; Takeuchi Y; Kobayashi K; Takahashi A; Yatoh S; Suzuki H; Sone H; Yamada N
    Diabetes; 2008 Sep; 57(9):2382-92. PubMed ID: 18458149
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.
    Yoshikawa T; Ide T; Shimano H; Yahagi N; Amemiya-Kudo M; Matsuzaka T; Yatoh S; Kitamine T; Okazaki H; Tamura Y; Sekiya M; Takahashi A; Hasty AH; Sato R; Sone H; Osuga J; Ishibashi S; Yamada N
    Mol Endocrinol; 2003 Jul; 17(7):1240-54. PubMed ID: 12730331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).
    Amemiya-Kudo M; Oka J; Takeuchi Y; Okazaki H; Yamamoto T; Yahagi N; Matsuzaka K; Okazaki S; Osuga J; Yamada N; Murase T; Shimano H
    J Biol Chem; 2011 Aug; 286(32):27902-14. PubMed ID: 21652712
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.
    Parton LE; McMillen PJ; Shen Y; Docherty E; Sharpe E; Diraison F; Briscoe CP; Rutter GA
    Am J Physiol Endocrinol Metab; 2006 Nov; 291(5):E982-94. PubMed ID: 16772326
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells.
    Li Y; Zhang Y; Li R; Chen W; Howell M; Zhang R; Chen G
    PLoS One; 2012; 7(9):e45210. PubMed ID: 23028851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.
    Yamashita T; Eto K; Okazaki Y; Yamashita S; Yamauchi T; Sekine N; Nagai R; Noda M; Kadowaki T
    Endocrinology; 2004 Aug; 145(8):3566-77. PubMed ID: 15059954
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells.
    Oberkofler H; Klein K; Felder TK; Krempler F; Patsch W
    Endocrinology; 2006 Feb; 147(2):966-76. PubMed ID: 16282353
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction.
    Shimano H; Amemiya-Kudo M; Takahashi A; Kato T; Ishikawa M; Yamada N
    Diabetes Obes Metab; 2007 Nov; 9 Suppl 2():133-9. PubMed ID: 17919187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of Insig-1 protects β cell against glucolipotoxicity via SREBP-1c.
    Chen K; Jin P; He HH; Xie YH; Xie XY; Mo ZH
    J Biomed Sci; 2011 Aug; 18(1):57. PubMed ID: 21843373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of differentiating pig preadipocytes by retinoic acid.
    Brandebourg TD; Hu CY
    J Anim Sci; 2005 Jan; 83(1):98-107. PubMed ID: 15583048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retinoids synergize with insulin to induce hepatic Gck expression.
    Chen G; Zhang Y; Lu D; Li NQ; Ross AC
    Biochem J; 2009 May; 419(3):645-53. PubMed ID: 19173678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.