137 related articles for article (PubMed ID: 34419448)
1. The yoga of Rag GTPases: Dynamic structural poses confer amino acid sensing by mTORC1.
Fingar DC
J Biol Chem; 2021 Sep; 297(3):101103. PubMed ID: 34419448
[TBL] [Abstract][Full Text] [Related]
2. An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
Egri SB; Shen K
J Biol Chem; 2021 Jul; 297(1):100861. PubMed ID: 34116056
[TBL] [Abstract][Full Text] [Related]
3. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
Shen K; Sabatini DM
Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
[TBL] [Abstract][Full Text] [Related]
4. Regulation of mTORC1 by the Rag GTPases.
Lama-Sherpa TD; Jeong MH; Jewell JL
Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
[TBL] [Abstract][Full Text] [Related]
5. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
6. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
[TBL] [Abstract][Full Text] [Related]
7. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
Peng M; Yin N; Li MO
Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925
[TBL] [Abstract][Full Text] [Related]
8. Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
Doxsey DD; Tettoni SD; Egri SB; Shen K
J Biol Chem; 2023 Jul; 299(7):104880. PubMed ID: 37269949
[TBL] [Abstract][Full Text] [Related]
9. Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.
Shen K; Choe A; Sabatini DM
Mol Cell; 2017 Nov; 68(3):552-565.e8. PubMed ID: 29056322
[TBL] [Abstract][Full Text] [Related]
10. Tissue-specific expression differences in Ras-related GTP-binding proteins in male rats.
Kincheloe GN; Roberson PA; Jefferson LS; Kimball SR
Physiol Rep; 2024 Feb; 12(3):e15928. PubMed ID: 38296461
[TBL] [Abstract][Full Text] [Related]
11. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM
Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980
[TBL] [Abstract][Full Text] [Related]
12. Rag GTPase in amino acid signaling.
Kim J; Kim E
Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
[TBL] [Abstract][Full Text] [Related]
13. Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
Cui Z; Napolitano G; de Araujo MEG; Esposito A; Monfregola J; Huber LA; Ballabio A; Hurley JH
Nature; 2023 Feb; 614(7948):572-579. PubMed ID: 36697823
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for the docking of mTORC1 on the lysosomal surface.
Rogala KB; Gu X; Kedir JF; Abu-Remaileh M; Bianchi LF; Bottino AMS; Dueholm R; Niehaus A; Overwijn D; Fils AP; Zhou SX; Leary D; Laqtom NN; Brignole EJ; Sabatini DM
Science; 2019 Oct; 366(6464):468-475. PubMed ID: 31601708
[TBL] [Abstract][Full Text] [Related]
15. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
[TBL] [Abstract][Full Text] [Related]
16. Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D; Yang Q; Wang H; Melick CH; Navlani R; Frank AR; Jewell JL
J Biol Chem; 2020 Mar; 295(10):2890-2899. PubMed ID: 32019866
[TBL] [Abstract][Full Text] [Related]
17. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y; Peterson TR; Shaul YD; Lindquist RA; Thoreen CC; Bar-Peled L; Sabatini DM
Science; 2008 Jun; 320(5882):1496-501. PubMed ID: 18497260
[TBL] [Abstract][Full Text] [Related]
18. Purification and biochemical characterization of the Rag GTPase heterodimer.
Doxsey DD; Shen K
Methods Enzymol; 2022; 675():131-158. PubMed ID: 36220268
[TBL] [Abstract][Full Text] [Related]
19. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
[TBL] [Abstract][Full Text] [Related]
20. Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Anandapadamanaban M; Masson GR; Perisic O; Berndt A; Kaufman J; Johnson CM; Santhanam B; Rogala KB; Sabatini DM; Williams RL
Science; 2019 Oct; 366(6462):203-210. PubMed ID: 31601764
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
