BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 34421821)

  • 1. L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
    Kuhre RE; Modvig IM; Jepsen SL; Kizilkaya HS; Bæch-Laursen C; Smith CA; Reimann F; Gribble FM; Rosenkilde MM; Holst JJ
    Front Endocrinol (Lausanne); 2021; 12():690387. PubMed ID: 34421821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans.
    Sun EW; Iepsen EW; Pezos N; Lumsden AL; Martin AM; Schober G; Isaacs NJ; Rayner CK; Nguyen NQ; de Fontgalland D; Rabbitt P; Hollington P; Wattchow DA; Hansen T; Holm JC; Liou AP; Jackson VM; Torekov SS; Young RL; Keating DJ
    Gastroenterology; 2021 Aug; 161(2):536-547.e2. PubMed ID: 33848536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms.
    Modvig IM; Kuhre RE; Jepsen SL; Xu SFS; Engelstoft MS; Egerod KL; Schwartz TW; Ørskov C; Rosenkilde MM; Holst JJ
    Am J Physiol Endocrinol Metab; 2021 May; 320(5):E874-E885. PubMed ID: 33645250
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon.
    Modvig IM; Christiansen CB; Rehfeld JF; Holst JJ; Veedfald S
    Physiol Rep; 2020 Jan; 8(2):e14352. PubMed ID: 31984675
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo.
    Panaro BL; Tough IR; Engelstoft MS; Matthews RT; Digby GJ; Møller CL; Svendsen B; Gribble F; Reimann F; Holst JJ; Holst B; Schwartz TW; Cox HM; Cone RD
    Cell Metab; 2014 Dec; 20(6):1018-29. PubMed ID: 25453189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels.
    Modvig IM; Smits MM; Galsgaard KD; Hjørne AP; Drzazga AK; Rosenkilde MM; Holst JJ
    Nutr Diabetes; 2024 Jun; 14(1):43. PubMed ID: 38862477
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion.
    Saltiel MY; Kuhre RE; Christiansen CB; Eliasen R; Conde-Frieboes KW; Rosenkilde MM; Holst JJ
    Nutrients; 2017 Apr; 9(4):. PubMed ID: 28441725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion.
    Panaro BL; Yusta B; Matthews D; Koehler JA; Song Y; Sandoval DA; Drucker DJ
    Mol Metab; 2020 Jul; 37():100990. PubMed ID: 32278655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine.
    Kuhre RE; Frost CR; Svendsen B; Holst JJ
    Diabetes; 2015 Feb; 64(2):370-82. PubMed ID: 25157092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice.
    Clemmensen C; Finan B; Fischer K; Tom RZ; Legutko B; Sehrer L; Heine D; Grassl N; Meyer CW; Henderson B; Hofmann SM; Tschöp MH; Van der Ploeg LH; Müller TD
    EMBO Mol Med; 2015 Mar; 7(3):288-98. PubMed ID: 25652173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1.
    Jepsen SL; Vestergaard ET; Larraufie P; Gribble FM; Reimann F; Jørgensen JOL; Holst JJ; Kuhre RE
    J Clin Endocrinol Metab; 2020 Jan; 105(1):266-75. PubMed ID: 31608930
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.
    Kuhre RE; Wewer Albrechtsen NJ; Larsen O; Jepsen SL; Balk-Møller E; Andersen DB; Deacon CF; Schoonjans K; Reimann F; Gribble FM; Albrechtsen R; Hartmann B; Rosenkilde MM; Holst JJ
    Mol Metab; 2018 May; 11():84-95. PubMed ID: 29656109
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP-protein kinase A pathway.
    Caruso C; Carniglia L; Durand D; Gonzalez PV; Scimonelli TN; Lasaga M
    Mol Cell Endocrinol; 2012 Jan; 348(1):47-54. PubMed ID: 21803120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus.
    Ramírez D; Saba J; Carniglia L; Durand D; Lasaga M; Caruso C
    Mol Cell Endocrinol; 2015 Aug; 411():28-37. PubMed ID: 25892444
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Islet MC4R Regulates PC1/3 to Improve Insulin Secretion in T2DM Mice via the cAMP and β-arrestin-1 Pathways.
    Ni Z; Wang Y; Shi C; Zhang X; Gong H; Dong Y
    Appl Biochem Biotechnol; 2022 Dec; 194(12):6164-6178. PubMed ID: 35900711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pancreatic neuronal melanocortin-4 receptor modulates serum insulin levels independent of leptin receptor.
    Mansour M; White D; Wernette C; Dennis J; Tao YX; Collins R; Parker L; Morrison E
    Endocrine; 2010 Feb; 37(1):220-30. PubMed ID: 20963574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Melanocortin type 4 receptor-mediated inhibition of A-type K
    Zhang Y; Jiang D; Li H; Sun Y; Jiang X; Gong S; Qian Z; Tao J
    J Biol Chem; 2019 Apr; 294(14):5496-5507. PubMed ID: 30745360
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice.
    Christiansen CB; Lind SJ; Svendsen B; Balk-Møller E; Dahlby T; Kuhre RE; Hartmann B; Mandrup-Poulsen T; Deacon CF; Wewer Albrechtsen NJ; Holst JJ
    Physiol Rep; 2018 Jul; 6(13):e13788. PubMed ID: 29981198
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Melanocortin-4 receptor activation inhibits c-Jun N-terminal kinase activity and promotes insulin signaling.
    Chai B; Li JY; Zhang W; Wang H; Mulholland MW
    Peptides; 2009 Jun; 30(6):1098-104. PubMed ID: 19463742
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors.
    Brighton CA; Rievaj J; Kuhre RE; Glass LL; Schoonjans K; Holst JJ; Gribble FM; Reimann F
    Endocrinology; 2015 Nov; 156(11):3961-70. PubMed ID: 26280129
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.