These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
196 related articles for article (PubMed ID: 34424810)
1. Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction. Park SY; Egan S; Cura AJ; Aron KL; Xu X; Zheng M; Borys M; Ghose S; Li Z; Lee K MAbs; 2021; 13(1):1963094. PubMed ID: 34424810 [TBL] [Abstract][Full Text] [Related]
3. Air sparging for prevention of antibody disulfide bond reduction in harvested CHO cell culture fluid. Mun M; Khoo S; Do Minh A; Dvornicky J; Trexler-Schmidt M; Kao YH; Laird MW Biotechnol Bioeng; 2015 Apr; 112(4):734-42. PubMed ID: 25384896 [TBL] [Abstract][Full Text] [Related]
4. Quantitative proteomics reveals cellular responses to individual mAb expression and tunicamycin in CHO cells. Sulaj E; Schwaigerlehner L; Sandell FL; Dohm JC; Marzban G; Kunert R Appl Microbiol Biotechnol; 2024 Jun; 108(1):381. PubMed ID: 38896138 [TBL] [Abstract][Full Text] [Related]
5. Comprehensive assessment of host cell protein expression after extended culture and bioreactor production of CHO cell lines. Hamaker NK; Min L; Lee KH Biotechnol Bioeng; 2022 Aug; 119(8):2221-2238. PubMed ID: 35508759 [TBL] [Abstract][Full Text] [Related]
6. Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing. Oh YH; Becker ML; Mendola KM; Choe LH; Min L; Lee KH; Yigzaw Y; Seay A; Bill J; Li X; Roush DJ; Cramer SM; Menegatti S; Lenhoff AM Biotechnol Bioeng; 2024 Apr; 121(4):1284-1297. PubMed ID: 38240126 [TBL] [Abstract][Full Text] [Related]
7. Glutathione and thioredoxin systems contribute to recombinant monoclonal antibody interchain disulfide bond reduction during bioprocessing. Handlogten MW; Zhu M; Ahuja S Biotechnol Bioeng; 2017 Jul; 114(7):1469-1477. PubMed ID: 28262915 [TBL] [Abstract][Full Text] [Related]
8. Host cell protein dynamics in the supernatant of a mAb producing CHO cell line. Tait AS; Hogwood CE; Smales CM; Bracewell DG Biotechnol Bioeng; 2012 Apr; 109(4):971-82. PubMed ID: 22124969 [TBL] [Abstract][Full Text] [Related]
9. Identification and characterization of co-purifying CHO host cell proteins in monoclonal antibody purification process. Liu X; Chen Y; Zhao Y; Liu-Compton V; Chen W; Payne G; Lazar AC J Pharm Biomed Anal; 2019 Sep; 174():500-508. PubMed ID: 31234041 [TBL] [Abstract][Full Text] [Related]
10. Online control of cell culture redox potential prevents antibody interchain disulfide bond reduction. Handlogten MW; Wang J; Ahuja S Biotechnol Bioeng; 2020 May; 117(5):1329-1336. PubMed ID: 31956991 [TBL] [Abstract][Full Text] [Related]
11. Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System. Velugula-Yellela SR; Powers DN; Angart P; Faustino A; Faison T; Kohnhorst C; Fratz-Berilla EJ; Agarabi CD J Vis Exp; 2019 May; (147):. PubMed ID: 31107445 [TBL] [Abstract][Full Text] [Related]
12. Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability. Chung WK; Russell B; Yang Y; Handlogten M; Hudak S; Cao M; Wang J; Robbins D; Ahuja S; Zhu M Biotechnol Bioeng; 2017 Jun; 114(6):1264-1274. PubMed ID: 28186329 [TBL] [Abstract][Full Text] [Related]
13. Multi-Omics Study on the Impact of Cysteine Feed Level on Cell Viability and mAb Production in a CHO Bioprocess. Ali AS; Raju R; Kshirsagar R; Ivanov AR; Gilbert A; Zang L; Karger BL Biotechnol J; 2019 Apr; 14(4):e1800352. PubMed ID: 30485675 [TBL] [Abstract][Full Text] [Related]
14. Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures. O'Mara B; Gao ZH; Kuruganti M; Mallett R; Nayar G; Smith L; Meyer JD; Therriault J; Miller C; Cisney J; Fann J Biotechnol Bioeng; 2019 Jul; 116(7):1669-1683. PubMed ID: 30883673 [TBL] [Abstract][Full Text] [Related]
15. Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors. Tan JG; Lee YY; Wang T; Yap MG; Tan TW; Ng SK Biotechnol J; 2015 May; 10(5):790-800. PubMed ID: 25740626 [TBL] [Abstract][Full Text] [Related]
16. Development and application of an analytical approach to assess an antibody's potential for disulfide reduction. Yang Y; Bastani N; Lagler SK; Harris D; Nagy A; Chen P; Patel A; Li Y; Gowetski DB; Lei QP Biotechnol Prog; 2022 Mar; 38(2):e3229. PubMed ID: 34962716 [TBL] [Abstract][Full Text] [Related]
17. Thioredoxin 1 is responsible for antibody disulfide reduction in CHO cell culture. Koterba KL; Borgschulte T; Laird MW J Biotechnol; 2012 Jan; 157(1):261-7. PubMed ID: 22138638 [TBL] [Abstract][Full Text] [Related]
18. Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS. Schelletter L; Albaum S; Walter S; Noll T; Hoffrogge R Appl Microbiol Biotechnol; 2019 Oct; 103(19):8127-8143. PubMed ID: 31420692 [TBL] [Abstract][Full Text] [Related]
19. Quantitative definition and monitoring of the host cell protein proteome using iTRAQ - a study of an industrial mAb producing CHO-S cell line. Chiverton LM; Evans C; Pandhal J; Landels AR; Rees BJ; Levison PR; Wright PC; Smales CM Biotechnol J; 2016 Aug; 11(8):1014-24. PubMed ID: 27214759 [TBL] [Abstract][Full Text] [Related]
20. Effect of the disulfide isomerase PDIa4 on the antibody production of Chinese hamster ovary cells. Komatsu K; Kumon K; Arita M; Onitsuka M; Omasa T; Yohda M J Biosci Bioeng; 2020 Dec; 130(6):637-643. PubMed ID: 32878739 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]