These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 34426156)

  • 1. Novel 1,3,4-thiadiazole/oxadiazole-linked honokiol derivatives suppress cancer via inducing PI3K/Akt/mTOR-dependent autophagy.
    Xu T; Tian W; Zhang Q; Liu J; Liu Z; Jin J; Guo Y; Bai LP
    Bioorg Chem; 2021 Oct; 115():105257. PubMed ID: 34426156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation.
    Zhang J; Wang X; Yang J; Guo L; Wang X; Song B; Dong W; Wang W
    Eur J Med Chem; 2020 Jan; 186():111897. PubMed ID: 31761382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Semisynthesis of novel magnolol-based Mannich base derivatives that suppress cancer cells via inducing autophagy.
    Xu T; Zheng Z; Guo Y; Bai LP
    Eur J Med Chem; 2020 Nov; 205():112663. PubMed ID: 32791403
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Semisynthesis and biological evaluation of novel honokiol thioethers against colon cancer cells HCT116 via inhibiting the transcription and expression of YAP protein.
    Yang R; Fu X; Fan J; Wang T; Song J; Xu T; Guo Y; Zhang SY
    Bioorg Med Chem; 2024 Jun; 107():117762. PubMed ID: 38759254
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Honokiol induces autophagy and apoptosis of osteosarcoma through PI3K/Akt/mTOR signaling pathway.
    Li Z; Dong H; Li M; Wu Y; Liu Y; Zhao Y; Chen X; Ma M
    Mol Med Rep; 2018 Feb; 17(2):2719-2723. PubMed ID: 29207060
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway.
    Lin CJ; Chen TL; Tseng YY; Wu GJ; Hsieh MH; Lin YW; Chen RM
    Toxicol Appl Pharmacol; 2016 Aug; 304():59-69. PubMed ID: 27236003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
    Ma Y; Yang X; Han H; Wen Z; Yang M; Zhang Y; Fu J; Wang X; Yin T; Lu G; Qi J; Lin H; Wang X; Yang Y
    Bioorg Chem; 2021 Jun; 111():104872. PubMed ID: 33838560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/mTOR signaling pathway in human breast cancer cells.
    Kamal A; Lakshma Nayak V; Nagesh N; Vishnuvardhan MV; Subba Reddy NV
    Bioorg Chem; 2016 Jun; 66():124-31. PubMed ID: 27149364
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy.
    Huang KJ; Kuo CH; Chen SH; Lin CY; Lee YR
    J Cell Mol Med; 2018 Mar; 22(3):1894-1908. PubMed ID: 29363886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration.
    Yeh PS; Wang W; Chang YA; Lin CJ; Wang JJ; Chen RM
    Cancer Lett; 2016 Jan; 370(1):66-77. PubMed ID: 26454217
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors.
    Jin XY; Chen H; Li DD; Li AL; Wang WY; Gu W
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):955-972. PubMed ID: 31072147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of novel benzimidazole derivatives as anti-cervical cancer agents through PI3K/Akt/mTOR pathway and tubulin inhibition.
    Li SS; Chen JJ; Zhang MM; Wang WX; Zhang WY; Ma C
    Eur J Med Chem; 2024 May; 271():116425. PubMed ID: 38636129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway.
    Szeliga M; Karpińska M; Rola R; Niewiadomy A
    Bioorg Chem; 2020 Dec; 105():104362. PubMed ID: 33074121
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
    Sun XL; Zhu ML; Dai YQ; Li HM; Li BH; Ma H; Zhang CH; Wu CZ
    Molecules; 2021 Jul; 26(14):. PubMed ID: 34299577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings.
    Li W; Sun Q; Song L; Gao C; Liu F; Chen Y; Jiang Y
    Eur J Med Chem; 2017 Dec; 141():721-733. PubMed ID: 29107429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of 2-(2-aminopyrimidin-5-yl)-4-morpholino-N-(pyridin-3-yl)quinazolin-7-amines as novel PI3K/mTOR inhibitors and anticancer agents.
    Peng W; Tu ZC; Long ZJ; Liu Q; Lu G
    Eur J Med Chem; 2016 Jan; 108():644-654. PubMed ID: 26731167
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors.
    Altıntop MD; Sever B; Akalın Çiftçi G; Turan-Zitouni G; Kaplancıklı ZA; Özdemir A
    Eur J Med Chem; 2018 Jul; 155():905-924. PubMed ID: 29966916
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 3-Arylamino-quinoxaline-2-carboxamides inhibit the PI3K/Akt/mTOR signaling pathways to activate P53 and induce apoptosis.
    Chen NY; Lu K; Yuan JM; Li XJ; Gu ZY; Pan CX; Mo DL; Su GF
    Bioorg Chem; 2021 Sep; 114():105101. PubMed ID: 34175723
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of new compounds bearing 3-(4-aminopiperidin-1-yl)methyl magnolol scaffold as anticancer agents for the treatment of non-small cell lung cancer via targeting autophagy.
    Zhao M; Zheng YH; Zhao QY; Zheng W; Yang JH; Pei HY; Liu L; Liu KJ; Xue LL; Deng DX; Wang L; Ma X; Fu SH; Peng AH; Tang MH; Luo YZ; Ye HY; Chen LJ
    Eur J Med Chem; 2021 Jan; 209():112922. PubMed ID: 33069436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.