BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 34426440)

  • 1. Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response.
    Yebra M; Bhargava S; Kumar A; Burgoyne AM; Tang CM; Yoon H; Banerjee S; Aguilera J; Cordes T; Sheth V; Noh S; Ustoy R; Li S; Advani SJ; Corless CL; Heinrich MC; Kurzrock R; Lippman SM; Fanta PT; Harismendy O; Metallo C; Sicklick JK
    Clin Cancer Res; 2022 Jan; 28(1):187-200. PubMed ID: 34426440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gastrointestinal stromal tumors - Summary of mutational status of the primary/secondary KIT/PDGFRA mutations, BRAF mutations and SDH defects.
    Kalfusova A; Linke Z; Kalinova M; Krskova L; Hilska I; Szabova J; Vicha A; Kodet R
    Pathol Res Pract; 2019 Dec; 215(12):152708. PubMed ID: 31708372
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic.
    Boikos SA; Pappo AS; Killian JK; LaQuaglia MP; Weldon CB; George S; Trent JC; von Mehren M; Wright JA; Schiffman JD; Raygada M; Pacak K; Meltzer PS; Miettinen MM; Stratakis C; Janeway KA; Helman LJ
    JAMA Oncol; 2016 Jul; 2(7):922-8. PubMed ID: 27011036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preferential MGMT methylation could predispose a subset of KIT/PDGFRA-WT GISTs, including SDH-deficient ones, to respond to alkylating agents.
    Ricci R; Martini M; Ravegnini G; Cenci T; Milione M; Lanza P; Pierconti F; Santini D; Angelini S; Biondi A; Rosa F; Alfieri S; Clemente G; Persiani R; Cassano A; Pantaleo MA; Larocca LM
    Clin Epigenetics; 2019 Jan; 11(1):2. PubMed ID: 30616628
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations.
    Janeway KA; Kim SY; Lodish M; Nosé V; Rustin P; Gaal J; Dahia PL; Liegl B; Ball ER; Raygada M; Lai AH; Kelly L; Hornick JL; ; O'Sullivan M; de Krijger RR; Dinjens WN; Demetri GD; Antonescu CR; Fletcher JA; Helman L; Stratakis CA
    Proc Natl Acad Sci U S A; 2011 Jan; 108(1):314-8. PubMed ID: 21173220
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Succinate dehydrogenase deficiency in a PDGFRA mutated GIST.
    Belinsky MG; Cai KQ; Zhou Y; Luo B; Pei J; Rink L; von Mehren M
    BMC Cancer; 2017 Aug; 17(1):512. PubMed ID: 28768491
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of insulin-like growth factor 1 receptor and frequent mutational inactivation of SDHA in wild-type SDHB-negative gastrointestinal stromal tumors.
    Belinsky MG; Rink L; Flieder DB; Jahromi MS; Schiffman JD; Godwin AK; von Mehren M
    Genes Chromosomes Cancer; 2013 Feb; 52(2):214-24. PubMed ID: 23109135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors.
    Italiano A; Chen CL; Sung YS; Singer S; DeMatteo RP; LaQuaglia MP; Besmer P; Socci N; Antonescu CR
    BMC Cancer; 2012 Sep; 12():408. PubMed ID: 22974104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA.
    Beadling C; Patterson J; Justusson E; Nelson D; Pantaleo MA; Hornick JL; Chacón M; Corless CL; Heinrich MC
    Cancer Med; 2013 Feb; 2(1):21-31. PubMed ID: 24133624
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST.
    Pantaleo MA; Astolfi A; Urbini M; Nannini M; Paterini P; Indio V; Saponara M; Formica S; Ceccarelli C; Casadio R; Rossi G; Bertolini F; Santini D; Pirini MG; Fiorentino M; Basso U; Biasco G;
    Eur J Hum Genet; 2014 Jan; 22(1):32-9. PubMed ID: 23612575
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Duodenal SDH-Deficient Gastrointestinal Stromal Tumor in a Patient With a Germline SDHB Mutation.
    Elston MS; Sehgal S; Dray M; Phillips E; Conaglen JV; Clifton-Bligh RJ; Gill AJ
    J Clin Endocrinol Metab; 2017 May; 102(5):1447-1450. PubMed ID: 28324028
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways.
    Pantaleo MA; Nannini M; Corless CL; Heinrich MC
    Cancer Med; 2015 Jan; 4(1):101-3. PubMed ID: 25165019
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metastatic SDH-Deficient GIST Diagnosed during Pregnancy: Approach to a Complex Case.
    Chennouf A; Zeidan E; Borduas M; Noël-Lamy M; Kremastiotis J; Beaudoin A
    Curr Oncol; 2022 Aug; 29(8):5933-5941. PubMed ID: 36005206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of IGF-1 receptor in KIT/PDGF receptor-α wild-type gastrointestinal stromal tumors with succinate dehydrogenase complex dysfunction.
    Nannini M; Astolfi A; Paterini P; Urbini M; Santini D; Catena F; Indio V; Casadio R; Pinna AD; Biasco G; Pantaleo MA
    Future Oncol; 2013 Jan; 9(1):121-6. PubMed ID: 23252569
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.
    Mason EF; Hornick JL
    Mod Pathol; 2013 Nov; 26(11):1492-7. PubMed ID: 23743927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Current management of succinate dehydrogenase-deficient gastrointestinal stromal tumors.
    Neppala P; Banerjee S; Fanta PT; Yerba M; Porras KA; Burgoyne AM; Sicklick JK
    Cancer Metastasis Rev; 2019 Sep; 38(3):525-535. PubMed ID: 31773431
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gastrointestinal Stromal Tumors: The GIST of Precision Medicine.
    Mei L; Smith SC; Faber AC; Trent J; Grossman SR; Stratakis CA; Boikos SA
    Trends Cancer; 2018 Jan; 4(1):74-91. PubMed ID: 29413424
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Good survival outcome of metastatic SDH-deficient gastrointestinal stromal tumors harboring SDHA mutations.
    Pantaleo MA; Lolli C; Nannini M; Astolfi A; Indio V; Saponara M; Urbini M; La Rovere S; Gill A; Goldstein D; Ceccarelli C; Santini D; Rossi G; Fiorentino M; Di Scioscio V; Fusaroli P; Mandrioli A; Gatto L; Catena F; Basso U; Ercolani G; Pinna AD; Biasco G
    Genet Med; 2015 May; 17(5):391-5. PubMed ID: 25188872
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Translational research and diagnosis in GIST].
    Wardelmann E
    Pathologe; 2012 Nov; 33 Suppl 2():273-7. PubMed ID: 22968735
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression.
    Chou A; Chen J; Clarkson A; Samra JS; Clifton-Bligh RJ; Hugh TJ; Gill AJ
    Mod Pathol; 2012 Sep; 25(9):1307-13. PubMed ID: 22555179
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.