194 related articles for article (PubMed ID: 34430599)
1. TGR5 protects against cholestatic liver disease via suppressing the NF-κB pathway and activating the Nrf2/HO-1 pathway.
Yang H; Luo F; Wei Y; Jiao Y; Qian J; Chen S; Gong Y; Tang L
Ann Transl Med; 2021 Jul; 9(14):1158. PubMed ID: 34430599
[TBL] [Abstract][Full Text] [Related]
2. Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice.
Yang H; Zhou H; Zhuang L; Auwerx J; Schoonjans K; Wang X; Feng C; Lu L
Liver Transpl; 2017 Jan; 23(1):63-74. PubMed ID: 27597295
[TBL] [Abstract][Full Text] [Related]
3. Anti-Inflammatory Activity of Dehydroandrographolide by TLR4/NF-κB Signaling Pathway Inhibition in Bile Duct-Ligated Mice.
Weng Z; Chi Y; Xie J; Liu X; Hu J; Yang F; Li L
Cell Physiol Biochem; 2018; 49(3):1083-1096. PubMed ID: 30196285
[TBL] [Abstract][Full Text] [Related]
4. AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-κB Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats.
Zhu H; Chai Y; Dong D; Zhang N; Liu W; Ma T; Wu R; Lv Y; Hu L
Can J Gastroenterol Hepatol; 2018; 2018():6181432. PubMed ID: 30662889
[TBL] [Abstract][Full Text] [Related]
5. The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice.
Wang YD; Chen WD; Yu D; Forman BM; Huang W
Hepatology; 2011 Oct; 54(4):1421-32. PubMed ID: 21735468
[TBL] [Abstract][Full Text] [Related]
6. Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation.
Gehrke N; Nagel M; Straub BK; Wörns MA; Schuchmann M; Galle PR; Schattenberg JM
Am J Physiol Gastrointest Liver Physiol; 2018 Mar; 314(3):G319-G333. PubMed ID: 29191940
[TBL] [Abstract][Full Text] [Related]
7. TGR5 agonist INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis.
Lyu D; Tang N; Wang J; Zhang Y; Chang J; Liu Z; Liu H
Int Immunopharmacol; 2019 Jun; 71():93-99. PubMed ID: 30878820
[TBL] [Abstract][Full Text] [Related]
8. Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.
Gong Z; Zhou J; Zhao S; Tian C; Wang P; Xu C; Chen Y; Cai W; Wu J
Oncotarget; 2016 Dec; 7(51):83951-83963. PubMed ID: 27924062
[TBL] [Abstract][Full Text] [Related]
9. Role of the G Protein-Coupled Bile Acid Receptor TGR5 in Liver Damage.
Reich M; Klindt C; Deutschmann K; Spomer L; Häussinger D; Keitel V
Dig Dis; 2017; 35(3):235-240. PubMed ID: 28249265
[TBL] [Abstract][Full Text] [Related]
10. Activation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line.
Mobraten K; Haugbro T; Karlstrom E; Kleiveland CR; Lea T
J Recept Signal Transduct Res; 2015; 35(5):402-9. PubMed ID: 25418122
[TBL] [Abstract][Full Text] [Related]
11. The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice.
Péan N; Doignon I; Garcin I; Besnard A; Julien B; Liu B; Branchereau S; Spraul A; Guettier C; Humbert L; Schoonjans K; Rainteau D; Tordjmann T
Hepatology; 2013 Oct; 58(4):1451-60. PubMed ID: 23686672
[TBL] [Abstract][Full Text] [Related]
12. Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex.
Rao J; Yang C; Yang S; Lu H; Hu Y; Lu L; Cheng F; Wang X
Int Immunol; 2020 May; 32(5):321-334. PubMed ID: 31930324
[TBL] [Abstract][Full Text] [Related]
13. Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study.
El-Agamy DS; Almaramhy HH; Ahmed N; Bojan B; Alrohily WD; Elkablawy MA
Cell Physiol Biochem; 2018; 47(2):523-534. PubMed ID: 29794447
[TBL] [Abstract][Full Text] [Related]
14. Protective effect of herbal medicine Huangqi decoction against chronic cholestatic liver injury by inhibiting bile acid-stimulated inflammation in DDC-induced mice.
Li WK; Wang GF; Wang TM; Li YY; Li YF; Lu XY; Wang YH; Zhang H; Liu P; Wu JS; Ma YM
Phytomedicine; 2019 Sep; 62():152948. PubMed ID: 31129431
[TBL] [Abstract][Full Text] [Related]
15. Limonin ameliorates acetaminophen-induced hepatotoxicity by activating Nrf2 antioxidative pathway and inhibiting NF-κB inflammatory response via upregulating Sirt1.
Yang R; Song C; Chen J; Zhou L; Jiang X; Cao X; Sun Y; Zhang Q
Phytomedicine; 2020 Apr; 69():153211. PubMed ID: 32259676
[TBL] [Abstract][Full Text] [Related]
16. TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.
Reich M; Deutschmann K; Sommerfeld A; Klindt C; Kluge S; Kubitz R; Ullmer C; Knoefel WT; Herebian D; Mayatepek E; Häussinger D; Keitel V
Gut; 2016 Mar; 65(3):487-501. PubMed ID: 26420419
[TBL] [Abstract][Full Text] [Related]
17. Anti-inflammatory effects of Aureusidin in LPS-stimulated RAW264.7 macrophages via suppressing NF-κB and activating ROS- and MAPKs-dependent Nrf2/HO-1 signaling pathways.
Ren J; Su D; Li L; Cai H; Zhang M; Zhai J; Li M; Wu X; Hu K
Toxicol Appl Pharmacol; 2020 Jan; 387():114846. PubMed ID: 31790703
[TBL] [Abstract][Full Text] [Related]
18. Glechoma hederacea extracts attenuate cholestatic liver injury in a bile duct-ligated rat model.
Wang YY; Lin SY; Chen WY; Liao SL; Wu CC; Pan PH; Chou ST; Chen CJ
J Ethnopharmacol; 2017 May; 204():58-66. PubMed ID: 28416441
[TBL] [Abstract][Full Text] [Related]
19. Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis.
Liu H; Pathak P; Boehme S; Chiang JL
J Lipid Res; 2016 Oct; 57(10):1831-1844. PubMed ID: 27534992
[TBL] [Abstract][Full Text] [Related]
20. Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Xiao H; Sun X; Liu R; Chen Z; Lin Z; Yang Y; Zhang M; Liu P; Quan S; Huang H
Pharmacol Res; 2020 Jan; 151():104559. PubMed ID: 31759089
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]