BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 34437915)

  • 1. The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane.
    Fiengo L; Lauro G; Bellone ML; Bifulco G; Dal Piaz F; De Tommasi N
    Int J Biol Macromol; 2021 Oct; 189():262-270. PubMed ID: 34437915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells.
    Dal Piaz F; Cotugno R; Lepore L; Vassallo A; Malafronte N; Lauro G; Bifulco G; Belisario MA; De Tommasi N
    J Proteomics; 2013 Apr; 82():14-26. PubMed ID: 23416714
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.
    Kim JA; Kim Y; Kwon BM; Han DC
    J Biol Chem; 2013 Oct; 288(40):28713-26. PubMed ID: 23983126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and energetics of an allele-specific genetic interaction between dnaJ and dnaK: correlation of nuclear magnetic resonance chemical shift perturbations in the J-domain of Hsp40/DnaJ with binding affinity for the ATPase domain of Hsp70/DnaK.
    Landry SJ
    Biochemistry; 2003 May; 42(17):4926-36. PubMed ID: 12718534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter.
    El-Kasaby A; Koban F; Sitte HH; Freissmuth M; Sucic S
    J Biol Chem; 2014 Oct; 289(42):28987-9000. PubMed ID: 25202009
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain.
    Sriram M; Osipiuk J; Freeman B; Morimoto R; Joachimiak A
    Structure; 1997 Mar; 5(3):403-14. PubMed ID: 9083109
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The four hydrophobic residues on the Hsp70 inter-domain linker have two distinct roles.
    Kumar DP; Vorvis C; Sarbeng EB; Cabra Ledesma VC; Willis JE; Liu Q
    J Mol Biol; 2011 Sep; 411(5):1099-113. PubMed ID: 21762702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The novolactone natural product disrupts the allosteric regulation of Hsp70.
    Hassan AQ; Kirby CA; Zhou W; Schuhmann T; Kityk R; Kipp DR; Baird J; Chen J; Chen Y; Chung F; Hoepfner D; Movva NR; Pagliarini R; Petersen F; Quinn C; Quinn D; Riedl R; Schmitt EK; Schitter A; Stams T; Studer C; Fortin PD; Mayer MP; Sadlish H
    Chem Biol; 2015 Jan; 22(1):87-97. PubMed ID: 25544045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A small molecule inhibitor of ATPase activity of HSP70 induces apoptosis and has antitumor activities.
    Ko SK; Kim J; Na DC; Park S; Park SH; Hyun JY; Baek KH; Kim ND; Kim NK; Park YN; Song K; Shin I
    Chem Biol; 2015 Mar; 22(3):391-403. PubMed ID: 25772468
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex.
    Taylor IR; Dunyak BM; Komiyama T; Shao H; Ran X; Assimon VA; Kalyanaraman C; Rauch JN; Jacobson MP; Zuiderweg ERP; Gestwicki JE
    J Biol Chem; 2018 Mar; 293(11):4014-4025. PubMed ID: 29414793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.
    Gotoh T; Terada K; Oyadomari S; Mori M
    Cell Death Differ; 2004 Apr; 11(4):390-402. PubMed ID: 14752510
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.
    Fewell SW; Smith CM; Lyon MA; Dumitrescu TP; Wipf P; Day BW; Brodsky JL
    J Biol Chem; 2004 Dec; 279(49):51131-40. PubMed ID: 15448148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40.
    Thirunavukarasu D; Shi H
    Nucleic Acid Ther; 2015 Apr; 25(2):103-12. PubMed ID: 25654640
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membrane-anchored heat-shock protein 70 (Hsp70) in cancer.
    Elmallah MIY; Cordonnier M; Vautrot V; Chanteloup G; Garrido C; Gobbo J
    Cancer Lett; 2020 Jan; 469():134-141. PubMed ID: 31669516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The carboxyl-terminal lobe of Hsc70 ATPase domain is sufficient for binding to BAG1.
    Brive L; Takayama S; Briknarová K; Homma S; Ishida SK; Reed JC; Ely KR
    Biochem Biophys Res Commun; 2001 Dec; 289(5):1099-105. PubMed ID: 11741305
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sub-lethal heat shock induces plasma membrane translocation of 70-kDa heat shock protein in viable, but not in apoptotic, U-937 leukaemia cells.
    Lasunskaia EB; Fridlianskaia I; Arnholdt AV; Kanashiro M; Guzhova I; Margulis B
    APMIS; 2010 Mar; 118(3):179-87. PubMed ID: 20132183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamics and mechanism of HSP70 translocation induced by photodynamic therapy treatment.
    Zhou F; Xing D; Chen WR
    Cancer Lett; 2008 Jun; 264(1):135-44. PubMed ID: 18321637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gentamicin inhibits HSP70-assisted protein folding by interfering with substrate recognition.
    Yamamoto S; Nakano S; Owari K; Fuziwara K; Ogawa N; Otaka M; Tamaki K; Watanabe S; Komatsuda A; Wakui H; Sawada K; Kubota H; Itoh H
    FEBS Lett; 2010 Feb; 584(4):645-51. PubMed ID: 20026329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hsp105alpha suppresses Hsc70 chaperone activity by inhibiting Hsc70 ATPase activity.
    Yamagishi N; Ishihara K; Hatayama T
    J Biol Chem; 2004 Oct; 279(40):41727-33. PubMed ID: 15292236
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATPase activity and ATP-dependent conformational change in the co-chaperone HSP70/HSP90-organizing protein (HOP).
    Yamamoto S; Subedi GP; Hanashima S; Satoh T; Otaka M; Wakui H; Sawada K; Yokota S; Yamaguchi Y; Kubota H; Itoh H
    J Biol Chem; 2014 Apr; 289(14):9880-6. PubMed ID: 24535459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.