239 related articles for article (PubMed ID: 34450034)
21. Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease.
Rolyan H; Feike AC; Upadhaya AR; Waha A; Van Dooren T; Haass C; Birkenmeier G; Pietrzik CU; Van Leuven F; Thal DR
J Neural Transm (Vienna); 2011 May; 118(5):699-712. PubMed ID: 21210284
[TBL] [Abstract][Full Text] [Related]
22. ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes.
Lee H; Cho S; Kim MJ; Park YJ; Cho E; Jo YS; Kim YS; Lee JY; Thoudam T; Woo SH; Lee SI; Jeon J; Lee YS; Suh BC; Yoon JH; Go Y; Lee IK; Seo J
Cell Rep; 2023 Oct; 42(10):113183. PubMed ID: 37777962
[TBL] [Abstract][Full Text] [Related]
23. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
24. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
25. Aβ promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer's disease.
Fernandez-Echevarria C; Díaz M; Ferrer I; Canerina-Amaro A; Marin R
Neuroscience; 2014 Oct; 278():354-66. PubMed ID: 25168729
[TBL] [Abstract][Full Text] [Related]
26. Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol.
Wang H; Kulas JA; Wang C; Holtzman DM; Ferris HA; Hansen SB
Proc Natl Acad Sci U S A; 2021 Aug; 118(33):. PubMed ID: 34385305
[TBL] [Abstract][Full Text] [Related]
27. Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.
Huang Y
Biochem Soc Trans; 2011 Aug; 39(4):924-32. PubMed ID: 21787325
[TBL] [Abstract][Full Text] [Related]
28. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
29. Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation.
Valencia-Olvera AC; Balu D; Faulk N; Amiridis A; Wang Y; Pham C; Avila-Munoz E; York JM; Thatcher GRJ; LaDu MJ
Neurotherapeutics; 2023 Jul; 20(4):1120-1137. PubMed ID: 37157042
[TBL] [Abstract][Full Text] [Related]
30. Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.
Prasad H; Rao R
Proc Natl Acad Sci U S A; 2018 Jul; 115(28):E6640-E6649. PubMed ID: 29946028
[TBL] [Abstract][Full Text] [Related]
31. Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target.
Ye S; Huang Y; Müllendorff K; Dong L; Giedt G; Meng EC; Cohen FE; Kuntz ID; Weisgraber KH; Mahley RW
Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18700-5. PubMed ID: 16344478
[TBL] [Abstract][Full Text] [Related]
32. Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes.
Azizidoost S; Babaahmadi-Rezaei H; Nazeri Z; Cheraghzadeh M; Kheirollah A
Biochim Biophys Acta Mol Cell Biol Lipids; 2022 Jan; 1867(1):159069. PubMed ID: 34744007
[TBL] [Abstract][Full Text] [Related]
33. Apolipoprotein E ε4 disrupts oligodendrocyte differentiation by interfering with astrocyte-derived lipid transport.
Mok KK; Yeung SH; Cheng GW; Ma IW; Lee RH; Herrup K; Tse KH
J Neurochem; 2023 Apr; 165(1):55-75. PubMed ID: 36549843
[TBL] [Abstract][Full Text] [Related]
34. Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes.
Rapp A; Gmeiner B; Hüttinger M
Biochimie; 2006 May; 88(5):473-83. PubMed ID: 16376010
[TBL] [Abstract][Full Text] [Related]
35. Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology.
Wu Q; Cortez L; Kamali-Jamil R; Sim V; Wille H; Kar S
Dis Model Mech; 2021 Oct; 14(10):. PubMed ID: 34524402
[TBL] [Abstract][Full Text] [Related]
36. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Honda K; Saito Y; Saito H; Toyoda M; Abe R; Saito T; Saido TC; Michikawa M; Taru H; Sobu Y; Hata S; Nakaya T; Suzuki T
Neurobiol Aging; 2023 Mar; 123():63-74. PubMed ID: 36638682
[TBL] [Abstract][Full Text] [Related]
37. Astrocytic APOE4 genotype-mediated negative impacts on synaptic architecture in human pluripotent stem cell model.
Watanabe H; Murakami R; Tsumagari K; Morimoto S; Hashimoto T; Imaizumi K; Sonn I; Yamada K; Saito Y; Murayama S; Iwatsubo T; Okano H
Stem Cell Reports; 2023 Sep; 18(9):1854-1869. PubMed ID: 37657448
[TBL] [Abstract][Full Text] [Related]
38. Roles of ApoE4 on the Pathogenesis in Alzheimer's Disease and the Potential Therapeutic Approaches.
Sun YY; Wang Z; Huang HC
Cell Mol Neurobiol; 2023 Oct; 43(7):3115-3136. PubMed ID: 37227619
[TBL] [Abstract][Full Text] [Related]
39. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
[TBL] [Abstract][Full Text] [Related]
40. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
Levi O; Dolev I; Belinson H; Michaelson DM
J Neurochem; 2007 Nov; 103(3):1031-40. PubMed ID: 17666042
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
