These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 34450493)

  • 21. Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
    Munier-Lehmann H; Pochet S; Dugue L; Dutruel O; Labesse G; Douget D
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):801-4. PubMed ID: 14565282
    [No Abstract]   [Full Text] [Related]  

  • 22. Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors.
    Naidu KM; Nagesh HN; Singh M; Sriram D; Yogeeswari P; Gowri Chandra Sekhar KV
    Eur J Med Chem; 2015 Mar; 92():415-26. PubMed ID: 25590862
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against
    Koseki Y; Kanetaka H; Tsunosaki J; Munier-Lehmann H; Aoki S
    Int J Mycobacteriol; 2017; 6(1):61-69. PubMed ID: 28317807
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of mycobacterial Thymidylate kinase inhibitors: a comprehensive pharmacophore, machine learning, molecular docking, and molecular dynamics simulation studies.
    Chikhale RV; Pawar SP; Kolpe MS; Shinde OD; Dahlous KA; Mohammad S; Patil PC; Bhowmick S
    Mol Divers; 2024 Aug; 28(4):1947-1964. PubMed ID: 39152354
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of inhibitors targeting polyketide synthase 13 of Mycobacterium tuberculosis as antituberculosis drug leads.
    Wang X; Zhao W; Wang B; Ding W; Guo H; Zhao H; Meng J; Liu S; Lu Y; Liu Y; Zhang D
    Bioorg Chem; 2021 Sep; 114():105110. PubMed ID: 34175719
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD
    Wang X; Ahn YM; Lentscher AG; Lister JS; Brothers RC; Kneen MM; Gerratana B; Boshoff HI; Dowd CS
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4426-4430. PubMed ID: 28827112
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
    Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
    J Chem Inf Model; 2009 Apr; 49(4):1070-8. PubMed ID: 19296716
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.
    Manallack DT; Pitt WR; Herdewijn P; Balzarini J; De Clercq E; Sanderson MR; Sohi M; Wien F; Munier-Lehmann H; Haouz A; Delarue M
    J Enzyme Inhib Med Chem; 2002 Jun; 17(3):167-74. PubMed ID: 12443042
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Crystal structure of dihydroneopterin aldolase from
    Czeczot AM; Muniz MN; Perelló MA; Silva ÉED; Timmers LFSM; Berger A; Gonzalez LC; Arraché Gonçalves G; Moura S; Machado P; Bizarro CV; Basso LA
    J Enzyme Inhib Med Chem; 2024 Dec; 39(1):2388207. PubMed ID: 39140692
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity.
    Gasse C; Douguet D; Huteau V; Marchal G; Munier-Lehmann H; Pochet S
    Bioorg Med Chem; 2008 Jun; 16(11):6075-85. PubMed ID: 18467107
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors.
    Sahu NU; Singh V; Ferraris DM; Rizzi M; Kharkar PS
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1714-1718. PubMed ID: 29699922
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Thiazole-aminopiperidine hybrid analogues: design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors.
    Jeankumar VU; Renuka J; Santosh P; Soni V; Sridevi JP; Suryadevara P; Yogeeswari P; Sriram D
    Eur J Med Chem; 2013; 70():143-53. PubMed ID: 24148991
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase.
    Eng WS; Rejman D; Pohl R; West NP; Woods K; Naesens LMJ; Keough DT; Guddat LW
    Eur J Med Chem; 2018 Nov; 159():10-22. PubMed ID: 30265958
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Knowledge based identification of potent antitubercular compounds using structure based virtual screening and structure interaction fingerprints.
    Kumar A; Chaturvedi V; Bhatnagar S; Sinha S; Siddiqi MI
    J Chem Inf Model; 2009 Jan; 49(1):35-42. PubMed ID: 19063713
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
    Matviiuk T; Rodriguez F; Saffon N; Mallet-Ladeira S; Gorichko M; de Jesus Lopes Ribeiro AL; Pasca MR; Lherbet C; Voitenko Z; Baltas M
    Eur J Med Chem; 2013; 70():37-48. PubMed ID: 24140915
    [TBL] [Abstract][Full Text] [Related]  

  • 36. First triclosan-based macrocyclic inhibitors of InhA enzyme.
    Rodriguez F; Saffon N; Sammartino JC; Degiacomi G; Pasca MR; Lherbet C
    Bioorg Chem; 2020 Jan; 95():103498. PubMed ID: 31855823
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors.
    Krishna VS; Zheng S; Rekha EM; Nallangi R; Sai Prasad DV; George SE; Guddat LW; Sriram D
    Eur J Med Chem; 2020 May; 193():112178. PubMed ID: 32171154
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Expansion of a novel lead targeting M. tuberculosis DHFR as antitubercular agents.
    Sharma K; Tanwar O; Deora GS; Ali S; Alam MM; Zaman MS; Krishna VS; Sriram D; Akhter M
    Bioorg Med Chem; 2019 Apr; 27(7):1421-1429. PubMed ID: 30827867
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors.
    Doğan H; Doğan ŞD; Gündüz MG; Krishna VS; Lherbet C; Sriram D; Şahin O; Sarıpınar E
    Eur J Med Chem; 2020 Feb; 188():112035. PubMed ID: 31951850
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents.
    Chiarelli LR; Mori M; Barlocco D; Beretta G; Gelain A; Pini E; Porcino M; Mori G; Stelitano G; Costantino L; Lapillo M; Bonanni D; Poli G; Tuccinardi T; Villa S; Meneghetti F
    Eur J Med Chem; 2018 Jul; 155():754-763. PubMed ID: 29940465
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.