BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 34454092)

  • 21. Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.
    Kluth O; Mirhashemi F; Scherneck S; Kaiser D; Kluge R; Neschen S; Joost HG; Schürmann A
    Diabetologia; 2011 Mar; 54(3):605-16. PubMed ID: 21107520
    [TBL] [Abstract][Full Text] [Related]  

  • 22. MicroRNA-96 regulates pancreatic β cell function under the pathological condition of diabetes mellitus through targeting Foxo1 and Sox6.
    Qi H; Yao L; Liu Q
    Biochem Biophys Res Commun; 2019 Nov; 519(2):294-301. PubMed ID: 31506178
    [TBL] [Abstract][Full Text] [Related]  

  • 23. FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes.
    Kim-Muller JY; Kim YJ; Fan J; Zhao S; Banks AS; Prentki M; Accili D
    J Biol Chem; 2016 May; 291(19):10162-72. PubMed ID: 26984405
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction.
    Kuo T; Damle M; González BJ; Egli D; Lazar MA; Accili D
    JCI Insight; 2019 May; 5(13):. PubMed ID: 31120862
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Angiotensin (1-7) reverses glucose-induced islet β cell dedifferentiation by Wnt/β-catenin/FoxO1 signalling pathway.
    Guo D; He J; Guo H; Song G; Peng L; An M; Wang C
    Endokrynol Pol; 2023; 74(5):544-552. PubMed ID: 37779373
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prolonged activation of NMDA receptors induces dedifferentiation of islet β cells in mice.
    Huang X; Xiong D; Deng L; Liu W; Tang S
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2022 Sep; 47(9):1182-1190. PubMed ID: 36411701
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.
    Chera S; Baronnier D; Ghila L; Cigliola V; Jensen JN; Gu G; Furuyama K; Thorel F; Gribble FM; Reimann F; Herrera PL
    Nature; 2014 Oct; 514(7523):503-7. PubMed ID: 25141178
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function.
    Talchai SC; Accili D
    Diabetes; 2015 Aug; 64(8):2868-79. PubMed ID: 25784544
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.
    Shao S; Nie M; Chen C; Chen X; Zhang M; Yuan G; Yu X; Yang Y
    J Cell Biochem; 2014 Jun; 115(6):1166-75. PubMed ID: 24415347
    [TBL] [Abstract][Full Text] [Related]  

  • 30. XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.
    Lee K; Chan JY; Liang C; Ip CK; Shi YC; Herzog H; Hughes WE; Bensellam M; Delghingaro-Augusto V; Koina ME; Nolan CJ; Laybutt DR
    Diabetologia; 2022 Jun; 65(6):984-996. PubMed ID: 35316840
    [TBL] [Abstract][Full Text] [Related]  

  • 31. SDF-1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up-regulating FoxO1 via binding to CXCR4.
    Chen XY; Shi YX; Huang YP; Ding M; Shen QL; Li CJ; Lin JN
    J Cell Mol Med; 2022 Feb; 26(3):750-763. PubMed ID: 34935260
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure.
    Fan J; Du W; Kim-Muller JY; Son J; Kuo T; Larrea D; Garcia C; Kitamoto T; Kraakman MJ; Owusu-Ansah E; Cirulli V; Accili D
    Mol Metab; 2020 Apr; 34():97-111. PubMed ID: 32180563
    [TBL] [Abstract][Full Text] [Related]  

  • 33. FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.
    Zhang T; Kim DH; Xiao X; Lee S; Gong Z; Muzumdar R; Calabuig-Navarro V; Yamauchi J; Harashima H; Wang R; Bottino R; Alvarez-Perez JC; Garcia-Ocaña A; Gittes G; Dong HH
    Endocrinology; 2016 Mar; 157(3):1055-70. PubMed ID: 26727107
    [TBL] [Abstract][Full Text] [Related]  

  • 34. PRMT1 promotes glucose toxicity-induced β cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells.
    Lv L; Chen H; Sun J; Lu D; Chen C; Liu D
    Endocrine; 2015 Aug; 49(3):669-82. PubMed ID: 25874535
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway.
    Song MY; Wang J; Ka SO; Bae EJ; Park BH
    Sci Rep; 2016 Jul; 6():30321. PubMed ID: 27457971
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway.
    Göncz E; Strowski MZ; Grötzinger C; Nowak KW; Kaczmarek P; Sassek M; Mergler S; El-Zayat BF; Theodoropoulou M; Stalla GK; Wiedenmann B; Plöckinger U
    Endocrinology; 2008 Apr; 149(4):1618-26. PubMed ID: 18162514
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism.
    Cochran BJ; Bisoendial RJ; Hou L; Glaros EN; Rossy J; Thomas SR; Barter PJ; Rye KA
    Arterioscler Thromb Vasc Biol; 2014 Oct; 34(10):2261-7. PubMed ID: 25147338
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.
    Martinez SC; Cras-Méneur C; Bernal-Mizrachi E; Permutt MA
    Diabetes; 2006 Jun; 55(6):1581-91. PubMed ID: 16731820
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Nov/Ccn3, a novel transcriptional target of FoxO1, impairs pancreatic β-cell function.
    Paradis R; Lazar N; Antinozzi P; Perbal B; Buteau J
    PLoS One; 2013; 8(5):e64957. PubMed ID: 23705021
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.
    Muhammad AB; Xing B; Liu C; Naji A; Ma X; Simmons RA; Hua X
    Am J Physiol Endocrinol Metab; 2017 Aug; 313(2):E148-E166. PubMed ID: 28270438
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.