136 related articles for article (PubMed ID: 34454298)
1. Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
Wang S; Wang X; Shao Y; Shao K; Wang Y; Guo X; Dong H; Zhao W; Li Y; Li G
Bioorg Chem; 2021 Nov; 116():105298. PubMed ID: 34454298
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis of novel celastrol derivatives and study on their antitumor growth through HIF-1α pathway.
Shang FF; Wang JY; Xu Q; Deng H; Guo HY; Jin X; Li X; Shen QK; Quan ZS
Eur J Med Chem; 2021 Aug; 220():113474. PubMed ID: 33930802
[TBL] [Abstract][Full Text] [Related]
3. Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.
Wang L; Chen G; Lu X; Wang S; Han S; Li Y; Ping G; Jiang X; Li H; Yang J; Wu C
Eur J Med Chem; 2015 Jan; 89():88-97. PubMed ID: 25462229
[TBL] [Abstract][Full Text] [Related]
4. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.
Wang JY; Wang Z; Li MY; Zhang Z; Mi C; Zuo HX; Xing Y; Wu YL; Lian LH; Xu GH; Piao LX; Ma J; Jin X
Chem Biol Interact; 2018 Dec; 296():134-144. PubMed ID: 30266538
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Sakai M; Takahashi N; Ikeda H; Furutani Y; Higuchi S; Suzuki T; Dohmae N; Kobayashi S; Harada H; Kojima S; Matsuura T; Hattori A; Kakeya H
Bioorg Med Chem; 2021 Sep; 46():116375. PubMed ID: 34492592
[TBL] [Abstract][Full Text] [Related]
6. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.
Xia Y; Jin Y; Kaur N; Choi Y; Lee K
Eur J Med Chem; 2011 Jun; 46(6):2386-96. PubMed ID: 21481991
[TBL] [Abstract][Full Text] [Related]
7. Discovery of Antimetastatic Chiral Ionone Alkaloid Derivatives Targeting HIF-1α/VEGF/VEGFR2 Pathway.
Liu JJ; Liu XY; Nie JP; Jia MQ; Yu Y; Qin N; Duan HQ
ChemMedChem; 2021 Jul; 16(13):2130-2145. PubMed ID: 33755334
[TBL] [Abstract][Full Text] [Related]
8. Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment.
Narise K; Okuda K; Enomoto Y; Hirayama T; Nagasawa H
Drug Des Devel Ther; 2014; 8():701-17. PubMed ID: 24944508
[TBL] [Abstract][Full Text] [Related]
9. Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors.
Kim HS; Hong M; Lee SC; Lee HY; Suh YG; Oh DC; Seo JH; Choi H; Kim JY; Kim KW; Kim JH; Kim J; Kim YM; Park SJ; Park HJ; Lee J
Eur J Med Chem; 2015 Nov; 104():157-64. PubMed ID: 26457742
[TBL] [Abstract][Full Text] [Related]
10. 2,2- dimethylbenzopyran derivatives containing pyridone structural fragments as selective dual-targeting inhibitors of HIF-1α and EZH2 for the treatment of lung cancer.
Xu H; Zhang J; Zhuang J; Chen Y; Chen L; Wang J; Cao R; Liu F; Wang K; Zhang X; Wang L; Chen G
Bioorg Chem; 2024 Jun; 147():107419. PubMed ID: 38703440
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of novel natural product-like diaryl acetylenes as hypoxia inducible factor-1 inhibitors and antiproliferative agents.
Wang S; Liu L; Guo X; Li G; Wang X; Dong H; Li Y; Zhao W
RSC Adv; 2019 Apr; 9(24):13878-13886. PubMed ID: 35519548
[TBL] [Abstract][Full Text] [Related]
12. Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives.
Sun XL; Zhu ML; Dai YQ; Li HM; Li BH; Ma H; Zhang CH; Wu CZ
Molecules; 2021 Jul; 26(14):. PubMed ID: 34299577
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible factor-1 (HIF-1) inhibitors.
Li G; Dong H; Ma Y; Shao K; Li Y; Wu X; Wang S; Shao Y; Zhao W
Bioorg Med Chem Lett; 2019 Aug; 29(16):2327-2331. PubMed ID: 31281016
[TBL] [Abstract][Full Text] [Related]
14. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Liu M; Liang Y; Zhu Z; Wang J; Cheng X; Cheng J; Xu B; Li R; Liu X; Wang Y
J Med Chem; 2019 Oct; 62(20):9299-9314. PubMed ID: 31556611
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and evaluation of benzofuran derivatives as novel anti-pancreatic carcinoma agents via interfering the hypoxia environment by targeting HIF-1α pathway.
Xu XL; Yang YR; Mo XF; Wei JL; Zhang XJ; You QD
Eur J Med Chem; 2017 Sep; 137():45-62. PubMed ID: 28554092
[TBL] [Abstract][Full Text] [Related]
16. Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α.
Shimizu T; Takahashi N; Huber VJ; Asawa Y; Ueda H; Yoshimori A; Muramatsu Y; Seimiya H; Kouji H; Nakamura H; Oguri H
Bioorg Med Chem; 2021 Jan; 30():115949. PubMed ID: 33360196
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and evaluation of HIF-1α inhibitory activities of novel panaxadiol derivatives.
Wang DY; Li YW; Zhang LH; Lv LY; Zhao YQ; Jin XJ; Piao HR
Bioorg Med Chem Lett; 2020 Dec; 30(24):127652. PubMed ID: 33130293
[TBL] [Abstract][Full Text] [Related]
18. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and structure-activity relationship of N-(piperidin-4-yl)benzamide derivatives as activators of hypoxia-inducible factor 1 pathways.
Huang ZN; Liang H; Qiao H; Wang BR; Qu N; Li H; Zhou RR; Wang LJ; Li SH; Li FN
Arch Pharm Res; 2018 Dec; 41(12):1149-1161. PubMed ID: 29998374
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and evaluation of novel ursolic acid derivatives as HIF-1α inhibitors with anticancer potential.
Chi KQ; Wei ZY; Wang KS; Wu J; Chen WQ; Jin XJ; Piao HR
Bioorg Chem; 2017 Dec; 75():157-169. PubMed ID: 28950243
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]